Bone marrow transplantation has emerged as a major form of
treatment for a broad range of human diseases. Marrow
transplantation has many unique biologic features and its
principles differ markedly from the transplantation of solid
organs. This volume overviews the present status of bone marrow
transplantation and summarizes recent progress and controversies.
Ad vances in defining the underlying biology of marrow
transplantation are discussed. The current status of several major
clinical problem areas are reviewed, including engraftment, acute
and chronic graft-versus-host dis ease, immunodeficiency, and
opportunistic infections. The therapeutic role of allogeneic and
autologous bone marrow transplantation is discussed, and results
are compared with alternative therapies. lX List of contributors
ANASETII, CLAUDIO, M. D. , Fred Hutchinson Cancer Research Center,
1124 Columbia Street, Seattle, Washington 98104 APPELBAUM, FRED, M.
D. , Fred Hutchinson Cancer Research Center, 1124 Columbia Street,
Seattle, Washington 98104 ARMITAGE, JAMES 0. , M. D. , Department
of Internal Medicine, Univer sity of Nebraska Medical Center, 42nd
and Dewey Avenue, Omaha, Nebraska 68105 BEATIY, PATRICK G. , M. D.
, Fred Hutchinson Cancer Research Center, 1124 Columbia Street,
Seattle, Washington 98104 BIERMAN, PHILIP J. , M. D. , Department
of Internal Medicine, Univer sity of Nebraska Medical Center, 42nd
and Dewey Avenue, Omaha, Nebraska 68105 BUTTURINI, ANNA, M. D. ,
Department of Pediatrics, University of Parma School of Medicine,
Parma, Italy CHAMPLIN, RICHARD, M. D.
General
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