Enormous advances in our knowledge of genetic contributions to
aging and disease, and in our understanding of the potential for
manipulation of the aging process, have taken place during the past
20 years. This is the first volume in decades to consolidate this
research in one place. It provides a broad and current overview of
the most promising advances in genetic research on aging, current
understanding of genetic contributions to the basic processes of
aging, and age-related disease. The Review focuses on the aging
process from lower organisms to man, and is organized in ascending
order of biological complexity starting with stem cells and
progressing through worms, flies, mice, and humans. Where relevant,
the Review also includes information about yeasts and non-human
primates.
The research presented in the Review uses a species-comparative
approach that makes finding cross species similarities (gene
conservation) and differences (gene differentiation) apparent. This
approach reflects the way in which the field is organized, making
it highly useful for investigators who want quick access and a
concise summary of a particular topic.
Key Features: Provides state-of-the-art information about
promising advances in genetic research on aging Comprises the first
comprehensive volume regarding genetic research about aging in
decades Authored by leading scholars in the field Disseminates
enormous advances in our understanding of the aging process
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