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Mass Spectrometry Data Analysis in Proteomics (Hardcover, 2007 ed.)
Loot Price: R5,299
Discovery Miles 52 990
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Mass Spectrometry Data Analysis in Proteomics (Hardcover, 2007 ed.)
Series: Methods in Molecular Biology, 367
Expected to ship within 12 - 17 working days
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Total price: R5,319
Discovery Miles: 53 190
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Mass Spectrometry Data Analysis in Proteomics is an in-depth guide
to the theory and practice of analyzing raw mass spectrometry (MS)
data in proteomics. As MS is a high throughput technique, proteomic
researchers must attend carefully to the associated field of data
analysis, and this volume outlines available bioinformatics
programs, algorithms, and databases available for MS data analysis.
General guidelines for data analysis using search engines such as
Mascot, Xtandem, and VEMS are provided, with specific attention to
identifying poor quality data and optimizing search parameters.
Several different types of MS data are discussed, followed by a
description of optimal methods for conversion of raw data into peak
lists for input to search engines. Choosing the most accurate and
complete databases is emphasized, and a report of available
sequence databases is included. Methods for assembling expressed
sequence tags (ESTs) into assembled nonredundant databases are
provided, along with protocols for further processing the sequences
into a format suitable for MS data. Mass Spectrometry Data Analysis
in Proteomics describes publicly available applications whenever
possible.
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