There is growing interest in the pronounced variability in the
incidence and severity of chronic respiratory diseases such as
asthma. It is now known that acute exacerbations are
multi-factorial in origin, with pollution, allergens and viruses
all implicated, and effective treatment requiring a similarly
complex approach that addresses each of the component causes. In
this new volume, leading authorities review what is known of these
causative factors and the mechanisms by which they exacerbate the
symptoms of pulmonary disease, both singly and in combination with
each other. The authors evaluate the individual efficacy of current
treatments in the light of this knowledge and present new
recommendations for formulating effective therapeutic regimens. Key
areas covered include: epidemiology; pathophysiology; in-vitro and
in-vivo experimental models of asthma exacerbation; treatment and
prevention of asthma exacerbations; and, delivery of care.
Addressing a topic of great interest, this is a key work for those
working in respiratory medicine, pulmonary medicine and immunology,
as well as for physiologists.
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