This book is intended as an introduction to the drug treatment of
cancer. It is almost ten years since the last edition was written.
In the intervening time, there have been numerous developments in
cancer chemotherapy and in order to cover these the majority of the
text has been completely revised and rewritten. In addition, two
new chapters have been introduced, one on the safe handling of
cytotoxic drugs and the other on biological response modifiers. In
order to incorporate this new information without any undue
increase in the length of the text the chapters on a combined
approach to treatment have been omitted. This is not because
interdisciplinary collaboration is no longer considered important
but is a reflection of the fact that, in most centres, it has
become the norm in cancer management and its central role in
successful treatment no longer needs to be stressed quite so
strongly. The four chapters in the last edition which dealt with
the team approach to cancer therapy have been replaced by a single
chapter on the place of chemotherapy in the overall treatment of
cancer. Unfortunately, despite all the innovations of the last
decade, it has become increasingly clear that much of the promise
offered by drug treatment during the 1960s and 1970s has not been
fulfilled.
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