The work presented in Thomas M. Gogsig's thesis deals with the
discovery of new metal-catalyzed transformations ranging from
Kumada-, Heck- and Suzuki-type reactions. The thesis starts with a
formidable introduction to Pd-catalyzed cross-coupling reactions.
New results have been obtained on: (i) Pd-catalyzed 1,2-migration
reactions, (ii) Pd-catalyzed Heck reactions employing
heteroaromatic tosylates, (iii) Ni-catalyzed Heck reactions, and
(iv) Pd-catalyzed carbonylative Heck reaction. Metal-catalyzed
cross-coupling reactions are today a highly competititve field (the
2010 Nobel Prize in Chemistry was awarded "for palladium-catalyzed
cross couplings in organic synthesis", the 2001 and 2005 Nobel
Prizes in closely related fields). Thomas M. Gogsig obtained new
results in his thesis that will help to improve the outcome of
catalytic processes and improve their scope. The results will thus
become key references for tomorrow's new applications. All chapters
include insightful discussions and in-depth descriptions of the key
principles of these new discoveries.
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