Tryptophan is not only an essential amino acid but also an
effective signaling molecule as an indicator of amino acid
sufficiency. Serotonin is biosynthesized from the essential amino
acid tryptophan. The first chapter of this book deals with the
effects of tryptophan as well as some strategies of treatments that
modify serotonin levels on cognitive processes during aging and
neurodegenerative diseases. The changes of tryptophan metabolism
under immunological challenges and physiological conditions like
stress are examined as well. In the third chapter, the authors
illustrate the key role of L-tryptophan in metabolic functions with
special emphasis on the alterations of circadian rhythms. The
remaining chapters of the book focus on new research findings on
L-tryptophan synthesis from D-serine; the complex experimental and
theoretical studies of the tryptophan molecule in its collisions
with low and high energy electrons; and finally, a commentary on a
novel tryptophan-selective amino acid transporter that is
functionally coupled to ID01-dependent signaling pathways.
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