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Plant Products in Dental Health - Plant Extracts against Dental Biofilm (Paperback)
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Plant Products in Dental Health - Plant Extracts against Dental Biofilm (Paperback)
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Scientific Study from the year 2013 in the subject Biology - Micro-
and Molecular Biology, grade: A, Nirma University (Institute of
Science), course: Microbiology, language: English, comment: This
study demonstrates the potential of plant products against
microbial biofilms., abstract: Extracts of Emblica officinalis
seeds prepared by Microwave Assisted Extraction (MAE) method were
evaluated for their antimicrobial property against planktonic form
of certain human/plant pathogenic microbes. Additionally, seed
extracts of E. officinalis, Tamarindus indica, Manilkara zapota,
Phoenix sylvestris, Syzygium cumini, and selected phytocompounds
were tested against multi-drug resistant Streptococcus mutans (a
major pathogen associated with human dental caries) in its
planktonic as well as biofilm form. Ability of these extracts to
eradicate and kill S. mutans biofilm was investigated. E.
officinalis extracts exerted bactericidal action against S. mutans,
Pseudomonas aeruginosa, and Vibrio cholerae. Acetone extract of S.
cumini, and curcumin were able to inhibit S. mutans at appreciably
low concentrations of 50 ug/mL and 20 ug/mL respectively. T. indica
and S. cumini seed extracts were able to kill 80% cells of S.
mutans in biofilm, in the concentration range of 500-1000 ug/mL.
These extracts were able to achieve 95% killing of S. mutans
biofilm at concentrations ranging from 600-2000 ug/mL. Ability of
the potent extracts to kill S. mutans biofilm did not seem to be
much dependent on eradication of the biofilm. Extraction efficiency
was found to have a good correlation with antibacterial activity.
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