Amino Acids Biosynthesis presents the current knowledge of
fundamental as well as applied microbiology of amino acids. Topics
discussed are the amino acid biosynthetic pathways, their genetic
and biochemical regulation, transport of amino acids and genomics
of producing microorganisms. The characterization of the control
mechanisms of amino acid biosynthesis has revealed insights into
principles of genetic and biochemical regulation, such as
transcriptional regulators and a new class of regulatory elements,
the riboswitch.
The volume further deals with the metabolic engineering of
microorganisms for the biotechnological production of amino acids
for use as pharmaceuticals and, particularly, as food and feed
additives. Comprehensive reviews are given of recent achievements
to enable or improve production of amino acids and dipeptides by
fermentation and enzyme catalysis. Here, the particular focus is on
metabolic engineering, the rational improvement of metabolic
functions using recombinant DNA technology.
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