Selected as a Doody's Core Title for 2022! For more than 30 years,
Designing Clinical Research has set the standard as the most
practical, authoritative guide for physicians, nurses, pharmacists,
and other practitioners involved in all forms of clinical and
public health research. Using a reader-friendly writing style, Drs.
Warren S. Browner, Thomas B. Newman, Steven R. Cummings, Deborah G.
Grady, Alison J. Huang, Alka M. Kanaya, and Mark J. Pletcher, all
of the University of California, San Francisco, provide up-to-date,
commonsense approaches to the challenging judgments involved in
designing, funding, and implementing a study. This state-of-the-art
fifth edition features new figures, tables, and design, as well as
new editors, new content, and extensively updated references to
keep you current. Covers clinical research in its many forms,
including clinical trials, observational studies, translational
science, and patient-oriented research. Presents epidemiologic
terms and principles and advanced conceptual material in a
practical and reader-friendly manner. Discusses key changes in the
field, including confounding and directed acyclic graphs, surrogate
outcomes and biomarkers, instrumental variables and Mendelian
randomization, regression discontinuity designs, alternative data
sources, AI and machine learning, pilot studies, as well as an
update on P values and Bayesian analysis.. Covers modifications of
classic randomized trials, such as pre/post, interrupted time
series, difference-in-differences, stepped wedge and cluster
randomized designs, as well as randomized trials in health systems.
Adds new chapters on qualitative approaches to clinical research
and on community-engaged research Enrich Your eBook Reading
Experience Read directly on your preferred device(s),such as
computer, tablet, or smartphone Easily convert to
audiobook,powering your content with natural language
text-to-speech
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