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Books > Medicine > General issues > Medical equipment & techniques > Medical research
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Computational Medicine - Tools and Challenges (Hardcover, 2012)
Loot Price: R5,387
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Computational Medicine - Tools and Challenges (Hardcover, 2012)
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Computational methodologies and modeling play a growing role for
investigating mechanisms, and for the diagnosis and therapy of
human diseases. This progress gave rise to computational medicine,
an interdisciplinary field at the interface of computer science and
medicine. The main focus of computational medicine lies in the
development of data analysis methods and mathematical modeling as
well as computational simulation techniques specifically addressing
medical problems. In this book, we present a number of
computational medicine topics at several scales: from molecules to
cells, organs, and organisms. At the molecular level, tools for the
analysis of genome variations as well as cloud computing resources
for medical genetics are reviewed. Then, an analysis of gene
expression data and the application to the characterization of
microbial communities are highlighted. At the protein level, two
types of analyses for mass spectrometry data are reviewed: labeled
quantitative proteomics and lipidomics, followed by protein
sequence analysis and a 3D structure and drug design chapter.
Finally, three chapters on clinical applications focus on the
integration of biomolecular and clinical data for cancer research,
biomarker discovery, and network-based methods for computational
diagnostics.
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