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If you're one of the billions of people in the world who work for
someone else, you'll definitely want to see what's inside Defective
Bosses: Working for the "Dysfunctional Dozen." This how-to,
how-not-to, why, and why-not tour guide is packed to the hilt with
a bevy of tested and proven survival skills and coping techniques
for those of you who are trapped in that daily labyrinth of mind
games and self-defeating work rituals--and all because of that
slightly off-center superior you have to answer to every day.
You'll find twelve of the most common defects presented to you in
clear and understandable terms so you can detect the defect,
protect state of mind, and correct the problem before your life at
the office becomes a complete wreck.Firmly grounded in psychiatric
literature, Defective Bosses takes you to levels of workplace
happiness that other similar publications fail to reach. In
contrast to other books that lack a solid theoretical base, this
comprehensive, systematic look at dysfunctional bosses takes an
in-depth look at twelve of the most prevalent disorders managers
and superiors inflict on their employees in the workplace, giving
equal treatment to each category and providing you with equal
strategies for each situation you might encounter. These and other
areas will help you turn your dead-end job into a dream occupation:
an overview of why we have defective bosses dealing with
self-centered bosses (narcissistic, sociopathic, paranoid, and
histrionic) handling controlling bosses (authoritarian,
obsessive-compulsive, explosive, and passive-aggressive) living
with neurotic bosses (masochistic, dependent, depressive, anxious)
end-of-the-chapter quizzes to help you diagnose your own boss "I
need it yesterday!" "Can you handle this for me? I've got the
company lunch." "If you don't get this in, it's your job!" If these
are all-too-common phrases in your workplace, then you need to make
a memo to yourself to order Defective Bosses. Its thorough
psychological base and examples gleaned from real-life scenarios
will give you so much guidance, advice, and direction for positive
change, you'll find that you're the boss when it comes to good
departmental relationships and a more mutually enjoyable work
environment.
When Andrew Carson joined the United States Army in 1941, he was
promised good food, travel, a supply of clothing, a place to sleep,
and thirty dollars a month. Within seven weeks, Private Carson was
shipped to the Philippines - with no boot camp, no training, not
one minute of close order drill. Captured by the Japanese less than
one year later, the young soldier endured the hardships of the
Cabanatuan prison camps, nearly died from dysentery, and then was
put aboard a Japanese hellship bound for Japan. There, he worked in
the Fukuoa coal mines, a virtual slave laborer until Japan
surrendered. This is the harrowing tale of one man's survival, and
how he came through the ordeal with dignity and respect for his
fellow soldiers.
If you're one of the billions of people in the world who work for
someone else, you'll definitely want to see what's inside Defective
Bosses: Working for the "Dysfunctional Dozen." This how-to,
how-not-to, why, and why-not tour guide is packed to the hilt with
a bevy of tested and proven survival skills and coping techniques
for those of you who are trapped in that daily labyrinth of mind
games and self-defeating work rituals--and all because of that
slightly off-center superior you have to answer to every day.
You'll find twelve of the most common defects presented to you in
clear and understandable terms so you can detect the defect,
protect state of mind, and correct the problem before your life at
the office becomes a complete wreck.Firmly grounded in psychiatric
literature, Defective Bosses takes you to levels of workplace
happiness that other similar publications fail to reach. In
contrast to other books that lack a solid theoretical base, this
comprehensive, systematic look at dysfunctional bosses takes an
in-depth look at twelve of the most prevalent disorders managers
and superiors inflict on their employees in the workplace, giving
equal treatment to each category and providing you with equal
strategies for each situation you might encounter. These and other
areas will help you turn your dead-end job into a dream occupation:
an overview of why we have defective bosses dealing with
self-centered bosses (narcissistic, sociopathic, paranoid, and
histrionic) handling controlling bosses (authoritarian,
obsessive-compulsive, explosive, and passive-aggressive) living
with neurotic bosses (masochistic, dependent, depressive, anxious)
end-of-the-chapter quizzes to help you diagnose your own boss "I
need it yesterday!" "Can you handle this for me? I've got the
company lunch." "If you don't get this in, it's your job!" If these
are all-too-common phrases in your workplace, then you need to make
a memo to yourself to order Defective Bosses. Its thorough
psychological base and examples gleaned from real-life scenarios
will give you so much guidance, advice, and direction for positive
change, you'll find that you're the boss when it comes to good
departmental relationships and a more mutually enjoyable work
environment.
Few things should go together better than psychology and law - and
few things are getting together less successfully. Edited by four
psychologists and a lawyer, and drawing on contributions from
Europe, the USA and Australia, "Applying Psychology to Criminal
Justice" argues that psychology should be applied more widely
within the criminal justice system. Contributors develop the case
for successfully applying psychology to justice by providing a rich
range of applicable examples for development now and in the future.
Readers are encouraged to challenge the limited ambition and
imagination of psychology and law by examining how insights in
areas such as offender cognition and decision-making under pressure
might inform future investigation and analysis.
Embryoimplantationisaremarkableandcomplexprocess. Approachesde-
velopedfromthefieldsofcellanddevelopmentalbiology,immunology,
andmolecularbiologyhavegreatlyenhancedourabilitytostudythe
sharedaswellasuniquefeaturesofembryo-uterineinteractions. Impres-
siveandcriticalgroundworkhasbeenlaidbyalargeanddedicatedarray
ofendocrinologists,reproductivebiologists,andanatomists.
Thesestudies
havesetthestagetoutilizesensitiveandsophisticatedtechniquestode-
tectandmodulateproteinandgeneexpression. Justasthesymbiosisofmother
andfetusiscriticalforthemaintenanceofpregnancy,soisthesynergyamong
investigatorsfrommanydisciplines,bothinbasicandclinicalarenas,keyto
unravelingthemysteriesofimplantationandplacentation. Alargegroupof
contributorsinthisfieldhadtheopportunitytomeetanddiscussthestateof
thisartwiththesupportofSeronoSymposiaUSA,Inc. Whileitisneverpos-
sibletobringtogethereveryonewhohasplayedanimportantrole,itwas,
nonetheless,bothexcitingandgratifyingtohavesomanycolleaguestogether
forthisevent.
Inthechaptersthatfollow,thehighlightsofthismeetingarepresented
assummarizedbytheindividualpresentersofsevendifferentsessions. The
topichasbeenconsideredfromthebroadsocialandethicalimplications
ofmoderninvitrofertilizationandassistedreproductivetechnologiesto
detailedmolecularcontrolsovereventsthatoccurduringembryonicdevel-
opment,uterinepreparationforimplantation,andplacentalorganogenesis.
Thesechaptersdemonstratethesignificantandrapidprogressbeingmade
inthisfieldofbiologyandmedicine. Atthesametime,theyshowthat
muchmoreneedstobedonetounderstandandfullyappreciatethispro- cess.
Lessonslearnedfromthiseffortcanbeexpectedtocontinuetopro-
videinsightsintoother,relatedfields. Ofthemanycontributorstoour
understandingoftheprocessofimplantation,nonehavehadalargerim-
pactthanourcolleague,AllenEnders. Dr. Endershasplayedaparamount
roleindevelopingthebasicunderstandingofthecellbiologicalprocesses
vii VIII Preface
underlyingimplantationandplacentationinmanyspecies,includinghu-
mans. Hecontinuestocontributeandguidethoughtintheseareas. The
participantsofthissymposiumrecognizedDr. Enders'impressivecontribu-
tionsbyholdingthiseventinhishonor. DANIELD. CARSON * Contents
Preface vii Contributors xiii PartI. Development and Future ofHuman
In Vitro Fertilization and Embryo Implantation I.
ImplantationintheHumanasViewedbyCanonLaw, CivilLaw,andNaturalReason
3 HOWARDW. JONES, JR. , RICHARDA. MCCORMICK, AND SUSAN L. CROCKIN
2. TheImpactofMaternalAgeandOvarianAge
onImplantationEfficiency...12 STEVEN SPANDORFER AND ZEV ROSENWAKS
Part II. CellularAspects ofImplantation 3.
VascularInvasionDuringImplantationandPlacentation 23 ALLEN C.
ENDERS AND THOMASN. BLANKENSHIP 4.
OxygenRegulatesHumanCytotrophoblastProliferation,
Differentiation,andInvasion:Implicationsfor
EndovascularInvasioninNormalPregnancy andPreeclampsia 39 OLGA
GENBACEV,YAN ZHOU, MICHAEL T. McMASTER, JOHNW. LUDLOW, CAROLINEH.
DAMSKY, AND SUSAN1. FISHER 5.
Embryo-MaternalInteractionsafterDiapause inaMarsupial 54 MARILYNB.
RENFREE AND GEOFFREY SHAW IX x Contents 6.
CellularInteractionsandtheCysteineProteinases
intheProcessofMouseImplantation 67 BRUCE BABIARZ, SUZANNE AFONSO,
ANDLINDA ROMAGNANO Part III. HormonalRegulation 7.
NovelSteroid-RegulatedMarkersofImplantation 83 INDRANIC. BAGCHI 8.
MolecularSignalinginImplantation 92 SANJOYK. DAS, BIBHASHC. PARIA,
AND SUDHANSU K. DEY 9. IdentificationofProgesterone-RegulatedGenes
intheUterus 107 CINDEER. FUNK, BERTW. O'MALLEY, AND FRANCESCO1.
DEMAYO PartIV. MolecularMarkersofReceptivity 10.
MucinsProvideaBarriertoEmbryoImplantation 123 MARYM. DESOUZA,
GULNARA. SURVEYOR, XINHUI ZHOU, JoANNE JULIAN, ANDDANIELD. CARSON
II. PotentialInvolvementofTrophinin,Bystin,
andTastininEmbryoImplantation 132 MICHIKON. FUKUDA, DAITA
NADANO,NAO SUZUKJ, AND JUN NAKAYAMA 12.
OsteopontininHumanEndometrium: ARoleinEndometrialReceptivityand
EmbryoImplantation? 141 CHRISTOS COUTIFARJS,AKINYINKA OMIGBODUN,
PIOTR ZIOLKIEWICZ, AND JOHN HOYER PartV. TrophoblastFactors 13.
TheRabbitasaModelforImplantation: InVivoandInVitroStudies 151
LORENH. HOFFMAN,D. RACHEL BREINAN, AND GARETHL. BLAEUER 14.
RegulationofTrophoblastEndocrineFunction:
ThePlacentaDoesItsOwnThingTranscriptionally...161 JEROMEF.
STRAUSSIII ANDLEE-CHUANKAo Contents XI 15.
TranscriptionFactorsRegulatingtheDifferentiation
oftheTrophoblastCellLineage 167 IANC. SCOTTANDJAMESC.
Embryoimplantationisaremarkableandcomplexprocess. Approachesde-
velopedfromthefieldsofcellanddevelopmentalbiology,immunology,
andmolecularbiologyhavegreatlyenhancedourabilitytostudythe
sharedaswellasuniquefeaturesofembryo-uterineinteractions. Impres-
siveandcriticalgroundworkhasbeenlaidbyalargeanddedicatedarray
ofendocrinologists,reproductivebiologists,andanatomists.
Thesestudies
havesetthestagetoutilizesensitiveandsophisticatedtechniquestode-
tectandmodulateproteinandgeneexpression. Justasthesymbiosisofmother
andfetusiscriticalforthemaintenanceofpregnancy,soisthesynergyamong
investigatorsfrommanydisciplines,bothinbasicandclinicalarenas,keyto
unravelingthemysteriesofimplantationandplacentation. Alargegroupof
contributorsinthisfieldhadtheopportunitytomeetanddiscussthestateof
thisartwiththesupportofSeronoSymposiaUSA,Inc. Whileitisneverpos-
sibletobringtogethereveryonewhohasplayedanimportantrole,itwas,
nonetheless,bothexcitingandgratifyingtohavesomanycolleaguestogether
forthisevent.
Inthechaptersthatfollow,thehighlightsofthismeetingarepresented
assummarizedbytheindividualpresentersofsevendifferentsessions. The
topichasbeenconsideredfromthebroadsocialandethicalimplications
ofmoderninvitrofertilizationandassistedreproductivetechnologiesto
detailedmolecularcontrolsovereventsthatoccurduringembryonicdevel-
opment,uterinepreparationforimplantation,andplacentalorganogenesis.
Thesechaptersdemonstratethesignificantandrapidprogressbeingmade
inthisfieldofbiologyandmedicine. Atthesametime,theyshowthat
muchmoreneedstobedonetounderstandandfullyappreciatethispro- cess.
Lessonslearnedfromthiseffortcanbeexpectedtocontinuetopro-
videinsightsintoother,relatedfields. Ofthemanycontributorstoour
understandingoftheprocessofimplantation,nonehavehadalargerim-
pactthanourcolleague,AllenEnders. Dr. Endershasplayedaparamount
roleindevelopingthebasicunderstandingofthecellbiologicalprocesses
vii VIII Preface
underlyingimplantationandplacentationinmanyspecies,includinghu-
mans. Hecontinuestocontributeandguidethoughtintheseareas. The
participantsofthissymposiumrecognizedDr. Enders'impressivecontribu-
tionsbyholdingthiseventinhishonor. DANIELD. CARSON * Contents
Preface vii Contributors xiii PartI. Development and Future ofHuman
In Vitro Fertilization and Embryo Implantation I.
ImplantationintheHumanasViewedbyCanonLaw, CivilLaw,andNaturalReason
3 HOWARDW. JONES, JR. , RICHARDA. MCCORMICK, AND SUSAN L. CROCKIN
2. TheImpactofMaternalAgeandOvarianAge
onImplantationEfficiency...12 STEVEN SPANDORFER AND ZEV ROSENWAKS
Part II. CellularAspects ofImplantation 3.
VascularInvasionDuringImplantationandPlacentation 23 ALLEN C.
ENDERS AND THOMASN. BLANKENSHIP 4.
OxygenRegulatesHumanCytotrophoblastProliferation,
Differentiation,andInvasion:Implicationsfor
EndovascularInvasioninNormalPregnancy andPreeclampsia 39 OLGA
GENBACEV,YAN ZHOU, MICHAEL T. McMASTER, JOHNW. LUDLOW, CAROLINEH.
DAMSKY, AND SUSAN1. FISHER 5.
Embryo-MaternalInteractionsafterDiapause inaMarsupial 54 MARILYNB.
RENFREE AND GEOFFREY SHAW IX x Contents 6.
CellularInteractionsandtheCysteineProteinases
intheProcessofMouseImplantation 67 BRUCE BABIARZ, SUZANNE AFONSO,
ANDLINDA ROMAGNANO Part III. HormonalRegulation 7.
NovelSteroid-RegulatedMarkersofImplantation 83 INDRANIC. BAGCHI 8.
MolecularSignalinginImplantation 92 SANJOYK. DAS, BIBHASHC. PARIA,
AND SUDHANSU K. DEY 9. IdentificationofProgesterone-RegulatedGenes
intheUterus 107 CINDEER. FUNK, BERTW. O'MALLEY, AND FRANCESCO1.
DEMAYO PartIV. MolecularMarkersofReceptivity 10.
MucinsProvideaBarriertoEmbryoImplantation 123 MARYM. DESOUZA,
GULNARA. SURVEYOR, XINHUI ZHOU, JoANNE JULIAN, ANDDANIELD. CARSON
II. PotentialInvolvementofTrophinin,Bystin,
andTastininEmbryoImplantation 132 MICHIKON. FUKUDA, DAITA
NADANO,NAO SUZUKJ, AND JUN NAKAYAMA 12.
OsteopontininHumanEndometrium: ARoleinEndometrialReceptivityand
EmbryoImplantation? 141 CHRISTOS COUTIFARJS,AKINYINKA OMIGBODUN,
PIOTR ZIOLKIEWICZ, AND JOHN HOYER PartV. TrophoblastFactors 13.
TheRabbitasaModelforImplantation: InVivoandInVitroStudies 151
LORENH. HOFFMAN,D. RACHEL BREINAN, AND GARETHL. BLAEUER 14.
RegulationofTrophoblastEndocrineFunction:
ThePlacentaDoesItsOwnThingTranscriptionally...161 JEROMEF.
STRAUSSIII ANDLEE-CHUANKAo Contents XI 15.
TranscriptionFactorsRegulatingtheDifferentiation
oftheTrophoblastCellLineage 167 IANC. SCOTTANDJAMESC.
Histone deacetylase inhibitors (HDIs) are good anti-cancer targets.
Histone acetyltransferases (HATs) and HDIs play opposite roles in
the regulation of gene expression via an epigenetic mechanism. HATs
catalyse the acetylation of lysine residues in histone tails,
facilitating and sustaining gene transcription. HDIs remove the
acetyl moieties from the epsilon-amine of lysine residues of
histone tails, leading to a more condensed form of chromatin and
preventing gene transcription. This book focuses on the use of HDIs
for the treatment of lymphoid malignancies; myeloid malignancies;
and breast cancer.
Cell Surface Carbohydrates and Cell Development summarizes
knowledge on the structure and function of cell surface
carbohydrates in development and differentiation. The chapters
include reviews on the expression of cell type-specific
carbohydrates and their roles in cell-cell interaction. In
particular, the role of cell surface carbohydrates in immune cell
response, malignant transformation, fertilization, and neural cell
development are addressed. This includes the exciting discovery
about the role of adhesive molecules in leukocyte-endothellium
interaction.
Cell Surface Carbohydrates and Cell Development also summarizes the
latest knowledge on structure and biosynthesis of carbohydrates,
the role of specific carbohydrate modification, and animal lectins.
The book will be useful to researchers and students interested in
the biology of glycoproteins and biotechnology.
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