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Histone Deacetylase Inhibitors (HDIs) - Pharmacology, Uses & Health Effects (Hardcover) Loot Price: R3,878
Discovery Miles 38 780
Histone Deacetylase Inhibitors (HDIs) - Pharmacology, Uses & Health Effects (Hardcover): Beverly D Carson

Histone Deacetylase Inhibitors (HDIs) - Pharmacology, Uses & Health Effects (Hardcover)

Beverly D Carson

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Loot Price R3,878 Discovery Miles 38 780 | Repayment Terms: R363 pm x 12*

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Histone deacetylase inhibitors (HDIs) are good anti-cancer targets. Histone acetyltransferases (HATs) and HDIs play opposite roles in the regulation of gene expression via an epigenetic mechanism. HATs catalyse the acetylation of lysine residues in histone tails, facilitating and sustaining gene transcription. HDIs remove the acetyl moieties from the epsilon-amine of lysine residues of histone tails, leading to a more condensed form of chromatin and preventing gene transcription. This book focuses on the use of HDIs for the treatment of lymphoid malignancies; myeloid malignancies; and breast cancer.

General

Imprint: nova science publishers
Country of origin: United States
Release date: June 2015
Editors: Beverly D Carson
Dimensions: 230 x 155 x 13mm (L x W x T)
Format: Hardcover
Pages: 95
ISBN-13: 978-1-63463-835-7
Categories: Books > Medicine > Other branches of medicine > Pharmacology > General
Books > Science & Mathematics > Biology, life sciences > Biochemistry > Enzymology
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LSN: 1-63463-835-2
Barcode: 9781634638357

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