I dare you to find even one page of this wonderful book that doesn't make you laugh. Linda and Shana are hysterical squared And I mean that in a good way...their musings made me smile, snort, and shout, 'Exactly right '-Debra Garfinkle, author of Storky: How I Lost My Nickname and Won the Girl (Putnam, 2005) Sex may take place in The City, but there's plenty of sass in the suburbs. While Linda Sharp and Shana Moore might cop to being housewives, these gals are far from desperate. Rather than finding their thrills with a pool boy, Sharp and Moore delight in taking the head-splitting struggles all women experience, and making you laugh until your sides have busted their seams. Linda and Shana tell it like you've experienced it...only this time around it's funny. Their flat out honest portrayals of PMS and unearned sweat; puppies and grown women who piddle; sagging breasts and husbands who often act like boobs, will leave you smiling, and feeling less alone in your leaky rowboat. Femail got me laughing out loud It's a celebration of friendship that's at once irreverent, feisty and heartfelt. -Alison van Diggelen, founder & editor of Silicon Mom 'Moore and Sharp unite tongue and

The 1991 Seminar on Stochastic Processes was held at the University of California, Los Angeles, from March 23 through March 25, 1991. This was the eleventh in a series of annual meetings which provide researchers with the opportunity to discuss current work on stochastic processes in an informal and enjoyable atmosphere. Previous seminars were held at Northwestern University, Princeton University, the University of Florida, the University of Virginia, the University of California, San Diego, and the University of British Columbia. Following the successful format of previous years there were five invited lectures. These were given by M. Barlow, G. Lawler, P. March, D. Stroock, M. Talagrand. The enthusiasm and interest of the participants created a lively and stimulating atmosphere for the seminar. Some of the topics discussed are represented by the articles in this volume. P. J. Fitzsimmons T. M. Liggett S. C. Port Los Angeles, 1991 In Memory of Steven Orey M. CRANSTON The mathematical community has lost a cherished colleague with the passing of Steven Orey. This unique and thoughtful man has left those who knew him with many pleasant memories. He has also left us with important contributions in the development of the theory of Markov processes. As a friend and former student, I wish to take this chance to recall to those who know and introduce to those who do not a portion of his lifework.

1. Introduction: The Brain-Immune Axis: Role of Opiates and Other Substances of Abuse, the Hypothalmic-Pituitary-Adrenal Axis and Behavior.- 2. Detection of ?-Opioid Receptor mRNA in Immature T Cells.- 3. Identification of Opioid Receptors in the Immune System Using a Novel Combination of Selective Opioid Ligands and Indirect Phycoerythrin Immunofluorescence.- 4. Kappa Opioid Receptors on Three Related Thymoma Cell Lines: Differences in Receptor-Effector Coupling.- 5. Delta Opioid Agonists Inhibit Proliferation of Highly Purified Murine CD4+ and CD8+ T-Cells.- 6. Mitogenic Activation of Human T Lymphocytes Induces a High Affinity Morphine Binding Site.- 7. Morphine-Induced Suppression of Thymocyte Proliferation Is Mediated by Inhibition of I1-2 Synthesis.- 8. Active ?-Endorphin Metabolites Generated by T-Cell Ectopeptidases.- 9. The Cellular Basis for Opioid-Induced Immunosuppression.- 10. Endogenous Opioid Peptides Suppress Cytokine-Mediated Upregulation of HIV-1 Expression in the Chronically Infected Promonocyte Clone U1.- 11. Relevance of Opioid Bimodality to Tolerance/Dependence Formation: From Transmitter Release to Second Messenger Formation.- 12. Agonist Induced Constitutive Receptor Activation As a Novel Regulatory Mechanism: ? Receptor Regulation.- 13. Expression of Cannabinoid Receptor mRNA in Murine and Human Leukocytes.- 14. Cannabinoid Stimulation of Arachidonate Metabolism in Human Peripheral Blood Mononuclear Leukocytes.- 15. Marijuana, Receptors and Immunomodulation.- 16. Mouse Strain Differences in in vivo and in vitro Immunosuppressive Effects of Opioids.- 17. The Clastogenicity of Morphine Sulfate in vivo.- 18. Cellular Mechanisms Involved in Morphine-Mediated Suppression of CTL Activity.- 19. Evidence for the Involvement of Macrophage-Derived Nitric Oxide in the Immunomodulatory Effect of Morphine and Aversive Pavlovian Conditioning.- 20. Mechanisms Whereby Macrophage-Derived Nitric Oxide Is Involved in the Immunomodulatory Effects of Morphine.- 21. Effects of Central Administration of Morphine on Immune Status in Lewis and Wistar Rats.- 22. Morphine Alteration of Histamine Release in vivo.- 23. Effect of Chronic Morphine Treatment on Immune Responses to Keyhole Limpet Hemocyanin in Swine.- 24. SIV Mutations Detected in Morphine-Treated Macaca mulatta Following SIVmac239 Infection.- 25. Adjuvant Effects on Morphine-Induced Suppression of Immune Responses to MN rgp120/HIV-1 in Mice.- 26. Possible Mechanisms of Immunotoxicity Following in vivo Exposure to the Inhalant, Isobutyl Nitrite.- 27. Role of Immune Processes in Peripheral Opioid Analgesia.- 28. Chronic Treatment with Morphine and Ethanol, but Not Cocaine, Attenuates I1-1? Activation of FOS Expression in the Rat Hypothalamic Paraventricular Nucleus.- 29. Effects of r-Hu-Interferon-?2A in the Brain.- 30. Quantification of Macrophage-Derived Substance P Receptor mRNA Using Competitive Polymerase Chain Reaction.- 31. HIV-1 Heterogeneity and Cytokines: Neuropathogenesis.

A groundbreaking collection of writings on the growing phenomenon of single-parent families in the United States, and how it impacts society as a whole. Focus on Single-Parent Families: Past, Present, and Future brings together in one volume a range of cutting-edge research articles and essays on what has become the most dynamic change in family structure in U.S. history. It is the only resource to make the most insightful and important work being done on the single-parent family phenomena accessible to general readers. Focus on Single-Parent Families helps readers go beyond the stereotypes and look closely at the complexity of families with one parent and consider their place in society. It encompasses the wide variety of households with a single parent—a family structure that promises to continue to grow and diversify. Throughout, the book gauges the impact of the increasing number of single-parent families on the nation as a whole, particularly in regard to policies concerning family welfare, children's services and health care, schools, and other essential social institutions.

Fractured rocks extend over much of the world, cropping out in shields, massifs, and the cores of major mountain ranges. They also form the basement below younger sedimentary rocks; at depth; they represent a continuous environment of extended and deep regional groundwater flow. Understanding of groundwater flow and solute transport in fractured rocks is vital for analysis of water resources, water quality and environmental protection, geotechnical and engineering projects, and geothermal energy production. Book chapters include theoretical and practical analyses using numerical modelling, geochemistry, isotopes, aquifer tests, laboratory tests, field mapping, geophysics, geological analyses, and some unique combinations of these types of investigation. Current water resource and geotechnical problems in many countries-and the techniques now used to address them-are also discussed. The importance of geological interpretation is re-emphasised in analysing the hydrogeology of fractured, mostly crystalline rocks and in how critical this is for understanding their hydrology and the wise utilisation of resources. This is indeed hydrogeology in its broadest sense. The importance of, but great difficulty in, extending or upscaling fractured rock hydraulic properties is also made clear. This book is aimed at practicing hydrogeologists, engineers, ecologists, resource managers, and perhaps most importantly, students and earth scientists not yet familiar with the ubiquity and importance of fractured rock systems.

The hydrogeologic environment of fractured rocks represents vital natural systems, examples of which occur on every continent. This book discusses key issues, methodologies and techniques in the hydrogeology of fractured rocks, summarizing recent progress and anticipating the outcome of future investigations. Forty-four revised and updated papers were selected from extended abstracts presented at the International Conference on Groundwater in Fractured Rocks, held in Prague in 2003 and these provide a valuable benchmark reference for studies in fractured rock hydrogeology worldwide. Topics include sustainable groundwater development, groundwater protection and management, new and improved approaches to the investigating hydrogeology of fractured systems, understanding of hydrogeologic properties both on local and regional scales, and both quantitative and qualitative aspects of groundwater flow and solute/contaminant transport.

This encyclopedic text focuses on the nature of Hispanic dialects, the spread of Spanish, and contemporary Spanish dialects in the Americas.

Do you work with angry children? Are you wondering why young people don't listen when they are angry? Are you exhausted from trying to understand angry behaviour? Are you having difficulty finding specialist help as soon as you need it? Anger Management is a practical guide that will help you to stay calm in the face of angry outbursts from children and young people, and support them in learning to manage their anger better. Written by chartered psychologists with extensive experience in the field, this helpful book will: increase your understanding of anger; offer you a range of practical management interventions; help you to manage your own behaviours to build more effective relationships; reduce the stress experienced by staff and parents who lack confidence in the face of aggressive behaviour. With stress and anger levels amongst young people at an all-time high, this third edition of Anger Management is particularly timely. It reflects significant developments in the fields of neuropsychology and our understanding of the physiology of emotions, as well as updated research into attachment theory, resilience, Acceptance and Commitment therapy and positive psychology. New sections include the importance of teaching forgiveness, gratitude and compassion, Mindfulness, the benefits of exercise, practical advice for Teaching Assistants and a 'how to' guide to managing risk. The book also discusses the revised Code of Practice for children and young people with Special Educational Needs and Disabilites (SEND 2014) and explores the implications of these changes for practitioners. Containing helpful worksheets, examples, explanations and practical advice, Anger Management provides targeted support for anyone working directly with children and young people to enable you to cope with angry behaviour in the best way possible, which is crucial for the wellbeing of adult and child alike. This book will prove invaluable to teachers as well as parents, teaching assistants, carers, psychologists, social workers and health care workers.

The hydrogeologic environment of fractured rocks represents vital natural systems, examples of which occur on every continent. This book discusses key issues, methodologies and techniques in the hydrogeology of fractured rocks, summarizing recent progress and anticipating the outcome of future investigations. Forty-four revised and updated papers were selected from extended abstracts presented at the International Conference on Groundwater in Fractured Rocks, held in Prague in 2003 and these provide a valuable benchmark reference for studies in fractured rock hydrogeology worldwide. Topics include sustainable groundwater development, groundwater protection and management, new and improved approaches to the investigating hydrogeology of fractured systems, understanding of hydrogeologic properties both on local and regional scales, and both quantitative and qualitative aspects of groundwater flow and solute/contaminant transport.

Presented from a criminal justice perspective, Cyberspace, Cybersecurity, and Cybercrime introduces students to the interdisciplinary field of cybercrime by exploring the theoretical, practical, and legal framework it operates under, along with strategies to combat it. Authors Janine Kremling and Amanda M. Sharp Parker provide a straightforward overview of cybercrime, cyberthreats, and the vulnerabilities individuals, businesses, and governments face everyday in a digital environment. Highlighting the latest empirical research findings and challenges that cybercrime and cybersecurity pose for those working in the field of criminal justice, this book exposes critical issues related to privacy, terrorism, hacktivism, the dark web, and much more. Focusing on the past, present, and future impact of cybercrime and cybersecurity, it details how criminal justice professionals can be prepared to confront the changing nature of cybercrime.

Learn to effectively deliver business aligned cybersecurity outcomes In The CISO Evolution: Business Knowledge for Cybersecurity Executives, information security experts Matthew K. Sharp and Kyriakos "Rock" Lambros deliver an insightful and practical resource to help cybersecurity professionals develop the skills they need to effectively communicate with senior management and boards. They assert business aligned cybersecurity is crucial and demonstrate how business acumen is being put into action to deliver meaningful business outcomes. The authors use illustrative stories to show professionals how to establish an executive presence and avoid the most common pitfalls experienced by technology experts when speaking and presenting to executives. The book will show you how to: Inspire trust in senior business leaders by properly aligning and setting expectations around risk appetite and capital allocation Properly characterize the indispensable role of cybersecurity in your company's overall strategic plan Acquire the necessary funding and resources for your company's cybersecurity program and avoid the stress and anxiety that comes with underfunding Perfect for security and risk professionals, IT auditors, and risk managers looking for effective strategies to communicate cybersecurity concepts and ideas to business professionals without a background in technology. The CISO Evolution is also a must-read resource for business executives, managers, and leaders hoping to improve the quality of dialogue with their cybersecurity leaders.

Do you work with angry children? Are you wondering why young people don't listen when they are angry? Are you exhausted from trying to understand angry behaviour? Are you having difficulty finding specialist help as soon as you need it? Anger Management is a practical guide that will help you to stay calm in the face of angry outbursts from children and young people, and support them in learning to manage their anger better. Written by chartered psychologists with extensive experience in the field, this helpful book will: increase your understanding of anger; offer you a range of practical management interventions; help you to manage your own behaviours to build more effective relationships; reduce the stress experienced by staff and parents who lack confidence in the face of aggressive behaviour. With stress and anger levels amongst young people at an all-time high, this third edition of Anger Management is particularly timely. It reflects significant developments in the fields of neuropsychology and our understanding of the physiology of emotions, as well as updated research into attachment theory, resilience, Acceptance and Commitment therapy and positive psychology. New sections include the importance of teaching forgiveness, gratitude and compassion, Mindfulness, the benefits of exercise, practical advice for Teaching Assistants and a 'how to' guide to managing risk. The book also discusses the revised Code of Practice for children and young people with Special Educational Needs and Disabilites (SEND 2014) and explores the implications of these changes for practitioners. Containing helpful worksheets, examples, explanations and practical advice, Anger Management provides targeted support for anyone working directly with children and young people to enable you to cope with angry behaviour in the best way possible, which is crucial for the wellbeing of adult and child alike. This book will prove invaluable to teachers as well as parents, teaching assistants, carers, psychologists, social workers and health care workers.

This volume represents the proceedings of the 2nd annual symposium on the Brain Immune Axis and Substance Abuse held at the Breakers Hotel in Palm Beach, FL in June 1994. The history of productive studies concerning the relationship between the nervous and the immune systems is relatively recent. Studies on the effects of drugs of abuse on the immune system and on infections among individuals who abuse drugs are also of recent vintage. Only in the last decade have investigators begun to describe the role of drugs of abuse and their endogenous counterparts on the brain-immune axis. Thus, the involvement of the neuroendocrine system in the interactions of drugs of abuse and the immune system has only recently been appreciated. In addition, it has been recognized that direct neural inputs impact immune function. Given the complexity of these interactions, characterization of biologically significant phenomena and elucidation of their mechanisms of action often requires a multidisciplinary approach. This meeting, on which the chapters in this book are based, brought together scientists from an array of biomedical disciplines whose work is focused on the effects of drugs of abuse on the neuro-endocrine immune axis. The meeting was unique in focusing on the brain-immune axis from the viewpoint of drugs of abuse rather than either immunity itself or the brain itself. Presentations addressed the direct effects of drugs of abuse on various components of the immune system, as well as those mediated indirectly by the central nervous system and the neuroendocrine system.

The 1991 Seminar on Stochastic Processes was held at the University of California, Los Angeles, from March 23 through March 25, 1991. This was the eleventh in a series of annual meetings which provide researchers with the opportunity to discuss current work on stochastic processes in an informal and enjoyable atmosphere. Previous seminars were held at Northwestern University, Princeton University, the University of Florida, the University of Virginia, the University of California, San Diego, and the University of British Columbia. Following the successful format of previous years there were five invited lectures. These were given by M. Barlow, G. Lawler, P. March, D. Stroock, M. Talagrand. The enthusiasm and interest of the participants created a lively and stimulating atmosphere for the seminar. Some of the topics discussed are represented by the articles in this volume. P. J. Fitzsimmons T. M. Liggett S. C. Port Los Angeles, 1991 In Memory of Steven Orey M. CRANSTON The mathematical community has lost a cherished colleague with the passing of Steven Orey. This unique and thoughtful man has left those who knew him with many pleasant memories. He has also left us with important contributions in the development of the theory of Markov processes. As a friend and former student, I wish to take this chance to recall to those who know and introduce to those who do not a portion of his lifework.

This volume represents the Proceedings of the Symposium on AIDS, Drugs of Abuse and the Neuroimmune Axis. This meeting was held in San Diego, California, November 11-13, 1995. As in the previous symposia in this series, productive studies were reviewed concerning the relationship between the nervous and the immune systems in regards to the relationship between drugs of abuse and infections, especially infections by the immunode ficiency virus that causes AIDS. In recent years, various investigators have begun to describe the role of illicit drugs and their endogenous counterparts on the brain-immune axis. It is widely recognized that the neuroendocrine system is intimately involved in the effects and manifestations of the interactions of drugs of abuse and the immune system. The meeting on which the chapters in this book are based brought together many biological scientists from an array of various scientific disciplines whose work is focused on the effects of drugs of abuse on the neuroendocrine-immune axis and its relationships to immunodeficiency caused by the AIDS virus. As in the past, the symposium was unique in focusing on the . brain-immune axis from the viewpoint of drugs of abuse rather than from the viewpoint of immunity or the brain itself."

Ferns are an integral part of the world's flora, appreciated for their beauty as ornamentals, problematic as invaders and endangered by human interference. They often dominate forest understories but also colonize open areas, invade waterways and survive in nutrient-poor wastelands and eroded pastures. Presented here is the first comprehensive summary of fern ecology, with worldwide examples from Siberia to the islands of Hawaii. Topics include a brief history of the ecological study of ferns, a global survey of fern biogeography, fern population dynamics, the role of ferns in ecosystem nutrient cycles, their adaptations to xeric environments and future directions in fern ecology. Fully illustrated concepts and processes provide a framework for future research and utilization of ferns for graduate students and professionals in ecology, conservation and land management.

Bribery is not a harmless tradition. It undermines a country's economy and puts all participants at risk. Smart business managers and international travelers know how to respect the culture while remaining on the safe side of the law. Here's how to make integrity work for you.