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The Brain Immune Axis and Substance Abuse (Paperback, Softcover reprint of the original 1st ed. 1995)
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The Brain Immune Axis and Substance Abuse (Paperback, Softcover reprint of the original 1st ed. 1995)
Series: Advances in Experimental Medicine and Biology, 373
Expected to ship within 10 - 15 working days
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This volume represents the proceedings of the 2nd annual symposium
on the Brain Immune Axis and Substance Abuse held at the Breakers
Hotel in Palm Beach, FL in June 1994. The history of productive
studies concerning the relationship between the nervous and the
immune systems is relatively recent. Studies on the effects of
drugs of abuse on the immune system and on infections among
individuals who abuse drugs are also of recent vintage. Only in the
last decade have investigators begun to describe the role of drugs
of abuse and their endogenous counterparts on the brain-immune
axis. Thus, the involvement of the neuroendocrine system in the
interactions of drugs of abuse and the immune system has only
recently been appreciated. In addition, it has been recognized that
direct neural inputs impact immune function. Given the complexity
of these interactions, characterization of biologically significant
phenomena and elucidation of their mechanisms of action often
requires a multidisciplinary approach. This meeting, on which the
chapters in this book are based, brought together scientists from
an array of biomedical disciplines whose work is focused on the
effects of drugs of abuse on the neuro-endocrine immune axis. The
meeting was unique in focusing on the brain-immune axis from the
viewpoint of drugs of abuse rather than either immunity itself or
the brain itself. Presentations addressed the direct effects of
drugs of abuse on various components of the immune system, as well
as those mediated indirectly by the central nervous system and the
neuroendocrine system.
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