This volume guides readers through the field of systems medicine by defining the terminology, and describing how established computational methods form bioinformatics and systems biology can be taken forward to an integrative systems medicine approach. Chapters provide an outlook on the role that systems medicine may or should play in various medical fields, and describe different facets of the systems medicine approach in action. Ultimately it introduces tools, resources and methodologies from bioinformatics and systems biology, and how to apply these in a systems medicine project. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, and discuss experimental and computational approaches, methods, and tools that should be considered for a successful systems medicine project. Systems Medicine aims to motivate and provide guidance for collaborations across disciplines to tackle today's challenges related to human health and well-being.

Despite significant demand for healthcare professionals in the workforce, admission to health professional graduate programs is highly competitive with less than half of all medical school applicants gaining admission annually. The application process is nuanced, complex, and costly, which can often be a significant barrier to otherwise highly qualified students, particularly those from backgrounds underrepresented in the healthcare workforce. Further understanding of the best practices in navigating the application processes, academia, and professional development is crucial for those advising pre-health students. The Handbook of Research on Advising and Developing the Pre-Health Professional Student considers current practices and research regarding academic and extracurricular preparation of undergraduate students who wish to enter health professions and offers new pre-health professional advisors as well as more seasoned advisors and other administrators a resource to assist them in their professional journey. Covering a range of topics such as advisor relationships and lifelong learning skills, this major reference work is ideal for advisors, healthcare professionals, academicians, researchers, practitioners, scholars, instructors, and students.

Bruce Ross knew something was wrong. He felt displaced and isolated from friends, family, and society. He had no one to turn to, and so he tried to cope with it himself. The fact that he had a disease called depression never entered his mind. He, like so many people, thought that only other people suffered from depression, not someone who appeared to be a well-adjusted, middle class person.

"From Dawn to Dusk to Daylight" chronicles Ross's journey and struggles with depression, from his high school years until middle age. During this time, his promising start in life transformed into a dusk, in which Ross lived twenty-four hours of each day in a gloomy and unsettled existence. With eloquence and charm, he recaptures the joys of his childhood in Dartmouth, growing up with his buddies. Gradually, those times faded, and he found himself in the middle of his teenage years and the beginnings of his depression.

Ross lived with the pain of depression and its "twin sister," Generalized Anxiety Disorder (GAD), for more than thirty-five years before achieving a breakthrough thanks to the experimental procedure known as Deep Brain Stimulation (DBS). This exciting advancement in medical science shows great promise for depression sufferers in North America and around the world.

"From Dawn to Dusk to Daylight" is the candid and revealing story of the trials and tribulations of living with depression and the relief DBS finally brought.

This book draws on medical sociology and science and technology studies to develop a novel conceptual framework for understanding innovation processes, using the case study of deep brain stimulation in paediatric neurology. It addresses key questions, including: How are promising and potentially disruptive new health technologies integrated into busy resource-constrained clinical contexts? What activities are involved in establishing a new clinical service? How do social and cultural forces shape these services, and importantly, how are understandings of 'health' and 'illness' reconfigured in the process? The book explores how the ideals of patient-centred medicine influence innovation in the clinic, and it introduces the concept of patient-centred proto-platforms. It argues that patient-centred innovation can constitute an expansion of medical power, as the clinical gaze is directed not only towards the body but also towards the patient as a social being. This will be an innovative and insightful read for academics and advanced students, as well as health service researchers with an interest in technology adoption processes.

"Advances in Quantum Chemistry" presents surveys of current topics in this rapidly developing field that has emerged at the cross section of the historically established areas of mathematics, physics, chemistry, and biology. It features detailed reviews written by leading international researchers. This volume focuses on thetheory of heavy ion physics in medicine.
"Advances in Quantum Chemistry" presents surveys of current topics in this rapidly developing field and this volume focuses on the theory of heavy ion physics in medicine."

"Decontamination in Hospitals and Healthcare "brings an understanding of decontamination practices and the development of technologies for cleaning and control of infection to a wide audience interested in public health, including healthcare specialists, scientists, students or patients.

Part one highlights the importance and history of decontamination in hospitals and healthcare before exploring the role of standards in decontamination, infection control in Europe, and future trends in the area. Part two focuses on decontamination practices in hospitals and healthcare. It considers the role of the nurse in decontamination, the issues of microbial biofilm in waterlines, control of waterborne microorganisms, and the use of gaseous decontamination technologies. Further chapters explore decontamination of prions, the use of protective clothing, no-touch automated room disinfection systems, and controlling the presence of microorganisms in hospitals. Part three discusses practices for decontamination and sterilization of surgical instruments and endoscopes. These chapters examine a range of guidance documents, including the choice framework for local policy and procedures for decontamination of surgical instruments, as well as novel technologies for cleaning and detection of contamination.

"Decontamination in Hospitals and Healthcare "provides a reference source on decontamination for public health professionals and students concerned with healthcare. It is particularly useful for scientists in microbiology and disinfection/decontamination laboratories, healthcare workers who use disinfectants, students in microbiology, clinicians, members of the Institute of Decontamination Sciences/Central Sterilising Club, and those employed in the Central Sterile Services departments of healthcare facilities.
Discusses decontamination processes in EuropeProvides an in-depth understanding into decontamination in healthcare settings, specifically hospitals and dental practicesExamines the decontamination of surgical equipment and endoscopes

As the demand for herbal medicines is increasing globally, the supply of medicinal plants is declining because most of this harvest is derived from wild and naturally growing resources. The genetic improvement of medicinal plants to produce higher yields and more active ingredients might help fulfil the increasing demand for medicinal plants. Medicinal plants are one of the most important sources of life-saving drugs for the world’s population. Increasing global demand for herbal medicines is accompanied by a dwindling supply of medicinal plants due to over-harvesting. Biotechnological interventions play a significant role in the improvement of crop yields and quality. Despite such progress in plant molecular biology, only limited biotechnology application has been seen in medicinal plants. Recent breakthroughs in high-throughput approaches have revolutionized this research area and shifted the focus towards omics approaches, such as genomics, transcriptomics, proteomics, and metabolomics. This book discusses these technologies. Currently, there is no existing publication that focuses on omics and medicinal plants.

Application of Artificial Intelligence in Early Detection of Lung Cancer presents the most up-to-date computer-aided diagnosis techniques used to effectively predict and diagnose lung cancer. The presence of pulmonary nodules on lung parenchyma is often considered an early sign of lung cancer, thus using machine and deep learning technologies to identify them is key to improve patients’ outcome and decrease the lethal rate of such disease. The book discusses topics such as basics of lung cancer imaging, pattern recognition techniques, deep learning, and nodule detection and localization. In addition, the book discusses risk prediction based on radiological analysis and 3D modeling. This is a valuable resource for cancer researchers, oncologists, graduate students, radiologists, and members of biomedical field who are interested in the potential of AI technologies in the diagnosis of lung cancer.

"Annual Reports in Medicinal Chemistry "provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
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Annual Reports in Medicinal Chemistry provides timely and critical reviews and this volume covers a important topicssuch as drug Discovery, Idiopathic Pulmonary Fibrosis and Neuraminidase Inhibitors ""

This book examines the future of birthing practices, particularly by focusing on epidural analgesia in childbirth. It describes historical and cultural trajectories that have shaped the way in which birth is understood in Western, developed nations. In setting out the nature of epidural history, knowledge and practice, the book delves into related birth practices within the hospital setting. By critically examining these practices, which are embedded in a scientific discourse that rationalises and relies upon technology use, the authors argue that epidural analgesia has been positioned as a safe technology in contemporary maternity culture, despite it carrying particular risks. In examining alternative research the book proposes that increasing epidural rates are not only due to greater pain relief requirements or access but are influenced by technocratic values and a fragmented maternity system. The authors outline the way in which this epidural discourse influences how information is presented to women and how this affects their choices around the use of pain relief in labour.

The prevalence of infectious diseases is worldwide increasing. Therefore, detection methods for infectious pathogens change quickly. In the 3rd edition of Kesslers Molecular Diagnostics of Infectious Diseases laboratory professionalists get valueable information about the current diagnostic methods, tipps and tricks in terms of sample processing, quality control, and interpretation of the results. For clinicians the book is a valuable aid for decision-making in ordering appropriate tests as well as in assuring the necessary quality of the sample material."