Bilateral Communication Between the Endocrine and Immune Systems, "Volume 7" in the Springer-Verlag "Endocrinology and " "Metabolism" Series, offers the most current information and recent advances in the area of communication and regulation between the Immune and Endocrine Systems. Immune-Endocrine Interactions are reported to play pivotal roles in both activation and down-regulation of immune responses and this volume provides the most up-to-date research and findings on the immune-endocrine relationship. The contributing authors are internationally recognized experts in this area and have written chapters on such diverse topics as Interactions between the Pituitary and Immune Systems, Effects of Estrogens and Androgens on Immune Response, The Role of Sex Steroids in Immune System Regulation, and Neuroendocrine and Thymus Interactions During Development and Aging. This volume is a must for all endocrinologists and endocrinology residents.

In this volume a distinguished group of internationally renowned clinicians and basic researchers discuss the present state of knowledge of the etiologyand pathogenesis of Dupuytren's contracture, a disease responsible for a considerable portion of disabilities within the working population allover the world. Although the riddle of how the contracture of the palmar fascia develops is still unsolved, the data on the pathobiochemistry and clinic of Dupuytren's Disease achieved in recent years has led to a better understanding of the biochemical and morphological processes underlying the deformation and malfunction of the afflicted tissues. Research in Dupuytren's Disease now enters the era of molecular medicine, which opens up new experimental means of studying the pathological changes which occur during the formation of the contracture on a molecular level. In particular, data are presented as to the role of specific biological macromolecules influencing the phenotype expression of the palmar fascia cells which are involved in autoimmune reactions and present both at the cell surface as well as in the extracellular matrix to regulate cell-to-cell and cell-to-matrix interactions. In vitro cell culture models to investigate fibro-cytic modulations are available and havebeen applied to study the effects of specific biological molecules on isolated cells from healthy palmar fascia and Dupuytren's contracture. Complementary evaluations of morphological, epidemiological, and clinical data contribute essentially to the present understanding of the etiology and pathogenesis of Dupuytren's Disease. This comprehensive and informative summary of the state of the art is completed by numerous references affixed to the individual contributions.

"Fractals in Biology and Medicine" explores the potential of fractal geometry for describing and understanding biological organisms, their development and growth as well as their structural design and functional properties. It extends these notions to assess changes associated with disease in the hope to contribute to the understanding of pathogenetic processes in medicine. The book is the first comprehensive presentation of the importance of the new concept of fractal geometry for biological and medical sciences. It collates in a logical sequence extended papers based on invited lectures and free communications presented at a symposium in Ascona, Switzerland, attended by leading scientists in this field, among them the originator of fractal geometry, Benoit Mandelbrot. "Fractals in Biology and Medicine" begins by asking how the theoretical construct of fractal geometry can be applied to biomedical sciences and then addresses the role of fractals in the design and morphogenesis of biological organisms as well as in molecular and cell biology. The consideration of fractal structure in understanding metabolic functions and pathological changes is a particularly promising avenue for future research.

This volume is based on the Field Museum of Natural History Spring System atics Symposium held in Chicago on May 11, 1991. The financial support of Ray and Jean Auel and of the Field Museum is gratefully acknowledged. When we teach or write, we present only those elements that support our arguments. We avoid all weak points of our debate and all the uncer tainties of our models. Thus, we offer hypotheses as facts. Multiauthored books like ours, which simultaneously advocate and question diverse views, avoid the pitfalls and lessen the impact of indoctrination. In this volume we analyze the anthropological and biological disagreements and the positions taken on the origins of modern humans, point out difficultieswith the inter pretations, and suggest that the concept of the human origin can be explained only when we first attempt to define Homo sapiens sapiens. One of the major controversies in physical anthropology concerns the geographic origin of anatomically modern humans. It is undisputed, due to the extensive research of the Leakeys and their colleagues, that the family Hominidae originated in Africa, but the geographic origin of Homo sapiens sapiens is less concretely accepted. Two schools of thought existon this topic."

The idea of editing this book was born in the winter of 1988/1989. Christian Endler was organizing the workshop 'Wasser und Information' (water and information) in Austria [1], and Jurgen Schulte was working on a publication of his results on atomic cluster stabilities and long-range electromagnetic interaction in atomic clusters. It was Franz Moser from the Technical University of Graz who brought these two together. After a talk that Moser had given in Bremen, Schulte explained to hirn his ideas about clusters and long range interaction, and his concern about reliable theories and experiments in research on ultra high dilutions (UHD) and homoeopathy. He was suggested to be a speaker at the Austrian workshop. Reviewing the contributions of this workshop and the current literature on UHD and homoeopathy, especially the PhD thesis by Giesela King [2] and the excellent survey by Marco Righetti [3], we decided to work on a book in order to critically encou rage more scientists to work and publish in this field with a high scientific standard. What we had in mind was a useful contribution to the goal to lift research on UHD and homoeo pathy to an internationally acceptable scientific standard, to encourage international scien tists to work in this area and to establish UHD and homoeopathy in academic science. Delayed by our individual academic careers in our specific fields, and delayed by lack of funds it took us about four years to finish this book.

All over Europe, asylum-seekers, immigrants and minorities are increasingly finding themselves under violent attack. Who are the perpetrators? What are their motives? To what extent are right-wing or neo-Nazi organizations involved? How do the authorities and the police respond? What are the roles of the media, the public opinion and anti-racist movements? What can be done to stop the violence? These are questions addressed in this volume by some of Europe's leading experts on racism and racist violence.

A savory account of how the pursuit of delicious foods shaped human evolution Nature, it has been said, invites us to eat by appetite and rewards by flavor. But what exactly are flavors? Why are some so pleasing while others are not? Delicious is a supremely entertaining foray into the heart of such questions. With generous helpings of warmth and wit, Rob Dunn and Monica Sanchez offer bold new perspectives on why food is enjoyable and how the pursuit of delicious flavors has guided the course of human history. They consider the role that flavor may have played in the invention of the first tools, the extinction of giant mammals, the evolution of the world's most delicious and fatty fruits, the creation of beer, and our own sociality. Along the way, you will learn about the taste receptors you didn't even know you had, the best way to ferment a mastodon, the relationship between Paleolithic art and cheese, and much more. Blending irresistible storytelling with the latest science, Delicious is a deep history of flavor that will transform the way you think about human evolution and the gustatory pleasures of the foods we eat.

The Trouble with Human Nature brings together biological and cross-cultural evidence to critically examine common preconceptions and challenge popular assumptions about human nature. It sets out to counter genetic and evolutionary myths about human variation and behavior, drawing on both biological and cultural anthropology, as well as from other disciplines including psychology, economics, and sociology. The chapters address the interrelated topics of health and disease, gender and other differences, and violence and conflict. The analysis calls into question the presumed natural foundation for social inequalities and sheds light on both the constraints and possibilities inherent in the human condition. This book provides students of human diversity and evolution with an excellent resource to better approach questions relating to human nature. It will also be of interest to those taking courses in social, cultural, and biological anthropology, as well as public health, medical anthropology, sociology, gender studies, psychology, and kinship studies.

In the beginning there was not only life but the ability to communicate and eventually to cooperate among the most basic, primeval creatures. In The Naked Neuron Dr. Joseph - an internationally respected neuroscientist and author of the highly praised The Right Brain and the Unconscious: Discovering the Stranger Within - takes us on an intriguing journey through time as he traces the evolution of communication and language from the most primitive single-celled animals to our earliest ancestors to humans today. As he so clearly demonstrates, we are linked to all levels of animals in a common bond of sensing, feeling, and communication. Be it singing wolves, dancing bees, or writhing rock and roll dancers, all communicate a treasure chest of meaning in the absence of the spoken word. Approximately 700 million years ago, a unique type of cell came into being - the neuron. This "naked" neuron, or nerve cell, lacked a protective fatty sheath. Still, it marked a monumental and world altering development, since it would become the building block of the brain. The naked neuron generated a revolutionary change resulting in a greater complexity and subtlety of thought. Dr. Joseph vividly depicts how neurons conferred on early humans advanced powers of mental and sensory acuity, including the gift of remembering one's past and contemplating the future. Although humans possess much of the same ancient brain tissue as our fellow primates, Dr. Joseph reveals to us the singular features of the human brain that have enabled humans uniquely to develop complex, spoken language. He holds us spellbound, revealing that although the new and old brain tissue are couched within the same brain, each often has difficulty understanding the impulses and language of the other. This ground-breaking book draws on Dr. Joseph's brilliant and original research and theories, fusing the latest discoveries made in neuroscience, sociobiology, and anthropology. He illuminates how the languages of th

The etiology of the Wimbum people in the Western Grassfields of Cameroon is described through an examination of the way in which the meanings of key concepts, used to interpret and explain illness and other forms of misfortune, are continually being produced and reproduced in the praxis of everyday communication. During the course of numerous dialogues, witchcraft, a highly ambivalent force, gradually emerges as the prime mover. As destructive cannibals or respectable elders the witches are the ultimate cause of all significant illness, misfortune and death, and as diviners they are also the ultimate judges who apportion moral responsibility. Even the ancestors and the traditional gods turn out to be fronts behind which the witches hide their activities.The study is on three levels: a medical anthropological exploration of explanations of illness and misfortune; a detailed ethnography of traditional African cosmology and witchcraft; and an examination of recent theoretical issues in anthropology such as the nature of ethnographic fieldwork and the possibility of dialogical or postmodern ethnography.

This volume, a study of a transhumant cattle-raising community in Spain, is based on the extensive fieldwork at La Nava de San Miguel, a village in the province of Avila in central Spain. It shows the social and economic factors upon which the continued vitality of this mountain village is based: the use of communal summer pastures; the transhumant groups which walk the cattle to the winter pastures over the mountains; and the system of taking turns for many tasks within the village. The book analyzes the dichotomy between the more rigid organization of life within the village and the organization of life outside the village, in the transhumant group which goes to the winter pastures in Extramadura.

Exploring the contemporary sources, scope and intensity of nationality conflicts in the context of a disintegrating Soviet Empire, the authors address themselves to the resurgence of ethnicity and nationalism within the former Soviet imperium, Yugoslavia, Hungary, Bulgaria and China, and the consquences of perestroika and glasnost. Kumar Rupesinghe has also written "Conflict Resolution in Uganda" and "Ethnic Conflicts and Human Rights". Olga Vorkunova is also the author of "Konflikti v 'Tretem Mire' i Zapad" (conflict in the "Third World" and the West) and "Skandinavia i Mezhdunarodnie Konflikti" (Scandinavia and international conflict).

Health and Other Unassailable Values sets out to examine health as a core cultural value. Taking 'health', 'evidence' and 'ethics' as her primary themes, Bell explores the edifice that underpins contemporary conceptions of health and the transformations in how we understand it, assess it and enact it. Although health, evidence and ethics have always been important values, she demonstrates that the grounds upon which they are grasped today are radically different from how they were formulated in the past. Divided into three parts, Part I focuses on the rise of epidemiology, Part II examines the emergence of evidence-based medicine, and Part III explores the broader ethical turn in health and medicine. Through an examination of core concepts including health behaviour, the randomised controlled trial, informed consent and human rights, Bell illustrates the ways in which certain entrenched ideas and assumptions about how human beings think and act recur across a variety of settings. An array of topical case studies, including cigarette packaging legislation, the incorporation of male circumcision as an HIV prevention tool, cancer screening technologies and e-cigarettes, ground the arguments presented. Written in a clear and engaging style, this volume will be of interest to a wide range of scholars and students, especially those in medical anthropology, medical sociology and public health. Clear chapter delineations make the work easy to engage with at the individual chapter level as well as a whole.

Traditionally, Non-Indian societies in Brazilian Amazonia - 'caboclo' - are treated by anthropologists as relics of the haphazard development of Amazonia - leftovers of the colonial enterprise and have therefore received little serious attention. This volume attempts to redress this imbalance by looking closely at the encompassing nature of peasant society in Brazilian Amazonia. The first part of the book is concerned with the concept of caboclo as it emerges in anthropological and Amazonianist disclosure. The second examines a historical 'caboclo' society (in Santarem, Para) from a broadly ethnographic viewpoint. Three different modes of peasant livelihood and their relation to the impact of the Transamazon Highway are then fully discussed, followed by a detailed examination of the 'sustainable- development' thesis using research from another part of Amazonia - the Guama River. Overall, this volume aims to examine the reasons for the relative 'invisibility' of caboclo society and to place it in a historical perspective.

A cultural history of the face in Western art, ranging from portraiture in painting and photography to film, theater, and mass media This fascinating book presents the first cultural history and anthropology of the face across centuries, continents, and media. Ranging from funerary masks and masks in drama to the figural work of contemporary artists including Cindy Sherman and Nam June Paik, renowned art historian Hans Belting emphasizes that while the face plays a critical role in human communication, it defies attempts at visual representation. Belting divides his book into three parts: faces as masks of the self, portraiture as a constantly evolving mask in Western culture, and the fate of the face in the age of mass media. Referencing a vast array of sources, Belting's insights draw on art history, philosophy, theories of visual culture, and cognitive science. He demonstrates that Western efforts to portray the face have repeatedly failed, even with the developments of new media such as photography and film, which promise ever-greater degrees of verisimilitude. In spite of sitting at the heart of human expression, the face resists possession, and creative endeavors to capture it inevitably result in masks--hollow signifiers of the humanity they're meant to embody. From creations by Van Eyck and August Sander to works by Francis Bacon, Ingmar Bergman, and Chuck Close, Face and Mask takes a remarkable look at how, through the centuries, the physical visage has inspired and evaded artistic interpretation.

Itisonlyrecently thatthe naturaloccurrenceoffree radicalsin biological tissue has become widely accepted, and that the suspi- cion with which biologists previously viewed the free radicals of radiationchemistryhas beenplacedin a broaderperspective. Now, oxygen-derived free radicals are considered respectable biochemi- cal intermediates, given always the caveat that unwanted tissue damage may arise if these active species are produced in such abundance that they overwhelm the natural antioxidant and free- radical defense mechanisms, or if these systems have become hypoeffective. Many factors, including several dietary manipula- tions, can lead toelevatedproductionofsuperoxide and may result in free radical overload, whereas a deficiency of those micronutri- ents associated with the antioxidant defense mec.hanisms may re- sult in substantially diminished antioxidant capacity. By now, antioxidants have become a household word and al- most everyone is aware of their imponance in protecting the body against attack by active oxygen species. Indeed, it is a paradox of nature that oxygen, which is so essential to sustain aerobic life, ul- timately contributes to its destruction. Not surprisingly, recogni- tion ofthis dilemma has generated a spate ofantioxidant strategies intended to reduce the risk of tissue damage by rampant oxygen radicals, some sadly based less on science than on speculation.

The stated aims of the Lecture Notes in Biomathematics allow for work that is "unfinished or tentative." This volume is offered in that spirit. The problem addressed is one of the classics of statistical ecology, the estimation of mortality rates from stage-frequency data, but in tackling it we found ourselves making use of ideas and techniques very different from those we expected to use, and in which we had no previous experience. Specifically we drifted towards consideration of some rather specific curve and surface fitting and smoothing techniques. We think we have made some progress (otherwise why publish?), but are acutely aware of the conceptual and statistical clumsiness of parts of the work. Readers with sufficient expertise to be offended should regard the monograph as a challenge to do better. The central theme in this book is a somewhat complex algorithm for mortality estimation (detailed at the end of Chapter 4). Because of its complexity, the job of implementing the method is intimidating. Any reader interested in using the methods may obtain copies of our code as follows: Intelligible Structured Code 1. Hutchinson and deHoog's algorithm for fitting smoothing splines by cross validation 2. Cubic covariant area-approximating splines 3. Cubic interpolating splines 4. Cubic area matching splines 5. Hyman's algorithm for monotonic interpolation based on cubic splines. Prototype User-Hostile Code 6. Positive constrained interpolation 7. Positive constrained area matching 8. The "full method" from chapter 4 9. The "simpler" method from chapter 4.

I am pleased to respond to the wish of the Editors, Drs A. Czeizel, H. G. Benk mann and H. W. Goedde and write the Foreword to this book "Genetics ofthe Hun garian population." This book represents the result of a fruitful international scientif ic cooperation, an endeavour that has been forged and sustained in the midst of a number of difficulties. It bears ample testimony to the fact that the pursuit of science transcends national boundaries and barriers and to what can be achieved through international cooperation. It has now become possible, among other things, to present a more meaningful characterization of the different ethnic groups than had been hitherto possible, thanks to the major advances in the study of human biology through the application of a wide variety of concepts and techniques. Several new disciplines, in particular, ecogenetics, pharmacogenetics and molecular biology have come into being and are flourishing. At the risk of stating the obvious, it is perhaps worth mentioning that the trends and place of migration and urbanization that we are witnessing today are such, that, before long, differences between different human gene pools may be substantially diminished, if not entirely obliterated. This book, therefore, is timely: it provides valuable information on who the Hungarians are, where they come from and where they are heading, in short, their past, present and future, in addition to presenting a broad perspective of some aspects of current research in biomedical sciences in Hungary."

Evolutionary ecology has grown into an exciting and dynamic area of research in the biological sciences. Only recently, however, has there been noteworthy progress in adapting theory, concepts, and models from this fi eld for analysis of human behavior and evolution.

Following recent events in Eastern Europe, questions surrounding European identity seem more pressing than ever. This volume explores, through a series of ethnographic case studies, the construction and experience of identities in Western Europe. All of the case studies are based on fieldwork, and in geographical scope range from Wales to the Basque country; from Corsica to the Lake District. The peoples they look at are similarly diverse: nationalists and members of the Communist party; rural and urban populations. The essays illustrate the ways in which detailed ethnographic case studies can illuminate how identities are lived by ordinary people.