This issue will discuss the techniques for various osteotomies of the foot and ankle. Articles included are: Osteotomies of the first ray for hallux abductovalgus correction, Central metatarsal osteotomies for deformity correction, Osteotomies of the fifth metatarsal, Minimal invasive surgery osteotomies for the forefoot/midfoot, Minimal invasive surgery osteotomies of hind foot/ankle, Corrective osteotomies used in pes planovalgus reconstruction, and many more!

This issue will focus on sports-related foot and ankle injuries, including articles on the following: Podiatrists as a member of the sports medicine team, New & emerging sports medicine technologies, Ankle sprains and return to sports activities, Dynamic clinical assessment techniques of the athlete, Acute lower extremity injuries, Principles of rehabilitation and return to sports following injury, and many more!

This book focuses on two fundamental aspects of brain-language relations: one concerns the neural organization of language in the healthy brain; the other challenges current approaches to treatment of aphasia and offers a new theory for recovery from aphasia. The essence of the book lies in the phrase neural multifunctionality: the constant and dynamic incorporation of non-linguistic functions into language models of the intact brain. The book makes the claim that language is a construction, created as we use it, and cannot be understood as being supported by neurally based linguistic networks only. Rather, language emerges from the constant and dynamic interaction among neural networks subserving cognitive, affective, and praxic functions with neural networks subserving lexical retrieval (naming), sentence processing (comprehension), and discourse (communication, conversation). In persons with stroke-induced aphasia, neural networks for executive system function, attention, memory, motor system function, visual system function, and emotion interact with neural networks for language to produce the aphasia profile and to influence recovery from aphasia. Consequently, neural multifunctionality in aphasia explains individual differences in the lesion-deficit model and continued recovery over time, redefining the concept of recovery from aphasia and offering new opportunities for treatment.

Disasters are confronting communities across the globe on a scale and intensity not previously witnessed. Following devastating earthquakes in Japan, New Zealand, Haiti, China, Indonesia and Pakistan, hurricanes in the Philippines and USA, floods in Bangladesh, the Balkans and Canada, famine and droughts in Africa and Australia, and ferocious wildfires in Europe, USA and Australia, to epidemics, conflicts and terrorism unleashing indiscriminate suffering across all continents... NO ONE IS IMMUNE... BUT SOME ARE MORE VULNERABLE THAN OTHERS. Allied health workers, including occupational therapists, are seeking ways to engage in a meaningful way...as professionals...individuals...and global citizens. Disaster and Development is a ground breaking book that crosses cultures and contexts to provide a foundation for critical reflection on the role of occupation in disaster and development. Drawing upon the experiences of survivors, and of practitioners, personnel from local and international organizations, researchers and academics, an occupational perspective is illuminated with implications for policy, practice and education. ENDORSEMENTS: WFOT - World Federation of Occupational Therapists "Timely, accessible, and reflecting the real life experiences of people who survive disaster and those that endeavour to help. At last, a unique resource that occupational therapists and others can count on in bringing about survivor-led recovery and resilience." Frank Kronenberg (co-editor, 'Occupational Therapy without Borders') "For students and practitioners this innovative book provides practical insights and guidance to assist individuals, families and communities affected by disaster and provides an important resource for this emerging area of practice." Case studies based on field experiences, include: responses to droughts, earthquakes, wildfires, and more:; survivor stories of trauma and healing; landmine action and advocacy (from local to global); accessibility and CBR in disaster recovery; empowerment approaches with vulnerable groups Practical considerations in promoting policy, practice and education Covers current/emerging disaster risks and local-global reduction strategies, including climate change Highlights processes, pitfalls and tips when entering the field Global perspective with contributions from Australia, USA, Canada, Bangladesh, Argentina, UK, Hong Kong...

Dr. Clete Kushida has assembled an expert panel of authors focused on Sleep Complaints. Articles in this issue include: Difficulty Falling or Staying Asleep; Irregular Bedtimes and Awakenings; Snoring, Irregular Respiration, Hypoventilation, and Apneas; Periodic or Rhythmic Movements During Sleep; Nightmares and Dream-Enactment Behaviors; Poor Sleep with Age; Difficulty Falling or Staying Asleep and more!

Evidence-Based Validation of Herbal Medicines brings together current thinking and practice in the areas of characterization and validation of natural products. This book reviews all aspects of evaluation and development of medicines from plant sources, including their cultivation, collection, phytochemical and phyto-pharmacological evaluation, and therapeutic potential. Emphasis is placed on describing the full range of evidence-based analytical and bio-analytical techniques used to characterize natural products, including -omic technologies, phyto-chemical analysis, hyphenated techniques, and many more.

Obesity is an increasing problem on a global scale, and strategies for its prevention involve experts from many disciplines including nutritionists, physicians, policy-makers and public health professionals. This book covers the latest advances in obesity development, management and prevention with specific focus on dietary interventions. Part one covers the development of obesity and key drivers for its continuation and increase. Part two looks at the role of specific dietary components in obesity management, and part three discusses the role of behavioural factors such as eating patterns in managing and preventing obesity. Part four focuses on structured dietary interventions for obesity treatment, and part five looks at public interventions and consumer issues.

Children with disabilities represent a unique population within pediatrics. Pediatric rehabilitation focuses on maximizing the function and enhancing the lives of children with a wide range of conditions such as cerebral palsy, spina bifida, stroke, brain injury, genetic abnormalities and other developmental disabilities.

Keeping tomorrow's nurses at the forefront of today's changing healthcare environment, Brunner & Suddarth's Textbook of Medical-Surgical Nursing, 15th Edition delivers the most comprehensive resource available for nursing students in the medical-surgical course. This bestselling text is designed for the way students like to learn, combining a highly readable approach with engaging case studies and learning tools to help students explore essential patient care practices in real-world terms and gain a more practical understanding of how they'll apply what they've learned in practice. Trusted by instructors, students, and practicing nurses for nearly 60 years, this landmark resource has been comprehensively updated for the 15th Edition to reflect the latest research, evidence-based practices, settings, issues, ethical challenges, and concerns of today's healthcare practice. Complete integration with Lippincott (R) CoursePoint+ allows you to easily map out your entire course, provide personalized student remediation, and simulate real-world nursing scenarios involving patients mentioned in vignettes in the text, giving your students unparalleled preparation for success in the medical-surgical nursing workforce.

Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable polymers and shaped biotextiles. The chapters in part two provide a comprehensive discussion of a range of different clinical applications of biotextiles, including surgical sutures, arterial prostheses, stent grafts, percutaneous heart valves and drug delivery systems.
This book provides a concise review of the technologies, properties and types of biotextiles used as medical devices. In addition, it addresses the biological dimension of how to design devices for different clinical applications, providing an invaluable reference for biomedical engineers of medical textiles, quality control and risk assessment specialists, as well as managers of regulatory affairs. The subject matter will also be of interest to professionals within the healthcare system including surgeons, nurses, therapists, sourcing and purchasing agents, researchers and students in different disciplines.
Provides an invaluable single source of information on the main types of textile materials and products used for medical implantsAddresses the technologies used and discusses the manufacture, properties and types of biotextilesExamines applications of biotextiles as medical implants, including drug delivery systems and stent grafts and percutaneous heart valves

Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.
The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.
This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials.
A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancerDiscusses the fundamentals of biomaterials for cancer therapeuticsDiscusses synthetic vaccines, proteins and polymers for cancer therapeutics

As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications.
Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications.
Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field.
Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devicesConsiders the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wiresConsiders the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives

Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications.
Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanical systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants.
With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies.
Provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of implantable sensor systems in a range of medical applicationsReviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, and microassemblyConsiders the challenges associated with implantable systems, including biocompatibility and sterilization

Carbon is light-weight, strong, conductive and able to mimic natural materials within the body, making it ideal for many uses within biomedicine. Consequently a great deal of research and funding is being put into this interesting material with a view to increasing the variety of medical applications for which it is suitable. Diamond-based materials for biomedical applications presents readers with the fundamental principles and novel applications of this versatile material.
Part one provides a clear introduction to diamond based materials for medical applications. Functionalization of diamond particles and surfaces is discussed, followed by biotribology and biological behaviour of nanocrystalline diamond coatings, and blood compatibility of diamond-like carbon coatings. Part two then goes on to review biomedical applications of diamond based materials, beginning with nanostructured diamond coatings for orthopaedic applications. Topics explored include ultrananocrystalline diamond for neural and ophthalmological applications, nanodiamonds for drug delivery systems, and diamond nucleation and seeding techniques for tissue regeneration. Finally, the book concludes with a discussion of diamond materials for microfluidic devices.
With its distinguished editors and international team of expert contributors, Diamond-based materials for biomedical applications is an authoritative guide for all materials scientists, researchers, medical practitioners and academics investigating the properties and uses of diamond based materials in the biomedical environment.
Presents the fundamental principles and novel applications of this versatile materialDiscusses the functionalization of diamond particles and surfaces, biotribology and biological behaviour of nanocrystalinediamond coatings and blood compatibility of diamond-like carbon coatingsReviews nanostructured diamond coatings for orthopaedic coatings

Maintaining the comprehensive coverage offered by the previous editions, this highly regarded text, now in its sixth edition and 32nd year of publication, is considered to be an indispensable resource for nurses and health care professionals engaged in the business of teaching and learning. Retaining the balance between theoretical issues and practical application, the text has been fully revised to reflect the most recent changes in nursing and nurse education including updated content on developments in teaching and learning, the introduction of the new NMC standards in the UK; developments in the NHS and the growing role of eLearning and technology.

Employed for both cosmetic and reconstructive purposes, breast implants are one of the most widely-used and controversial prostheses available. The development of safe, reliable products is vital to the future of this important field of surgery. Biomaterials in plastic surgery reviews the history, materials and safety issues associated with breast implants.
Beginning with an introduction to the history of biomaterials used for breast augmentation, Biomaterials in plastic surgery goes on to discuss development issues. It then discusses the chemistry and physical properties of biomedical silicones before reviewing cohesive gel and polyurethane foam implants. The book concludes by analysing the epidemiological evidence on the safety issues relating to breast implants, followed by a review of retrieval and analysis of breast implants emphasizing strength, durability and failure mechanisms.
With its distinguished editors and international team of expert contributors, Biomaterials in plastic surgery is an important guide for surgeons, manufacturers and all those researching this important field.
Comprehensively examines the history, materials and safety issues associated with breast implantsProvides an overview of the history of biomaterials used for breast augmentation and goes on to discuss the development and chemical and physical properties of biomedical siliconesReviews cohesive gel breast implants and polyurethane foam breast implants

Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks.
Discusses a range of ab initio models for protein structure predictionIntroduces a unique model based on experimental observationsDescribes various methods for the quantitative assessment of the presented models from the viewpoint of information theory

Medical devices play an important role in the field of medical and health technology, and encompass a wide range of health care products. Directive 2007/47/EC defines a medical device as any instrument, apparatus, appliance, software, material or other article, whether used alone or in combination, including the software intended by its manufacturer to be used specifically for diagnostic and/or therapeutic purposes and necessary for its proper application, intended by the manufacturer to be used for human beings. The design and manufacture of medical devices brings together a range of articles and case studies dealing with medical device R&D. Chapters in the book cover materials used in medical implants, such as Titanium Oxide, polyurethane, and advanced polymers; devices for specific applications such as spinal and craniofacial implants, and other issues related to medical devices, such as precision machining and integrated telemedicine systems.
Contains articles on a diverse range of subjects within the field, with internationally renowned specialists discussing each medical deviceOffers a practical approach to recent developments in the design and manufacture of medical devicesPresents a topic that is the focus of research in many important universities and centres of research worldwide

Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of medical polymers reviews the performance of both bioresorbable and non-bioresorbable medical polymers.
Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices.
With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians.
Comprehensively examines the performance of both bioresorbable and non-bioresorbable medical polymersDiscusses the processing of bioresorbable and other polymers for medical applications, before reviewing the degradation of bioresorbable medical polymersExplores the durability and reliability of non-bioresorbable medical polymers and discusses wear processes in polymer implants and ageing processes of biomedical polymers in the body

The Neonatal Resuscitation Program (R) (NRP (R)) course conveys an evidence-based approach to care of the newborn at birth and facilitates effective team-based care for healthcare professionals who care for newborns at the time of delivery. NRP utilizes a blended learning approach, which includes online testing and hands-on case-based simulation/debriefing that focus on critical leadership, communication, and team-work skills. The NRP, 8th Edition, introduces a new educational methodology to better meet the needs of health care professionals who manage the newly born baby. New in the 8th edition: Key Points at the beginning of each lesson. Quick response (QR) codes that enable the reader to view short videos about the topic on their mobile device. Lesson Review Questions grouped together at the end of each lesson. Quality Improvement Opportunities and Frequently Asked Questions in each lesson. New sections in Lesson 10 (Special Considerations) about resuscitation of the newborn with a myelomeningocele or an abdominal wall defect. Three Supplemental Lessons (Improving Resuscitation Team Performance, Resuscitation Outside the Delivery Room, and Bringing Quality Improvement to Your Resuscitation Team) that all NRP users to enhance their resuscitation knowledge and performance.

The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications.
The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices.
With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings.
Provides an extensive review of coating types and surface modifications for biomedical applicationsChapters look at hydrophilic coatings for biomedical applications in and ex vivo, mineral coatings for orthopaedic applications, pyrolytic carbon coating and other commonly-used biomedical coatingsPresents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices

This volume in the "Methods in Enzymology" series comprehensively covers Cancer, Cardiovascular and the central nervous system of Nanomedicine. With an international board of authors, this volume is split into sections that cover subjects such as Diabetes and nanotechnology as potential therapy, Nanomedicines for inflammatory diseases, and Development and use of ceramide nanoliposomes in cancer.
Comprehensively covers cancer and the cardiovascular and central nervous systems of nanomedicineAn international board of authorsSplit into sections that cover subjects such as diabetes and nanotechnology as potential therapy, nanomedicines for inflammatory diseases, and the development and use of ceramide nanoliposomes in cancer

Although hip, knee and other orthopaedic implants are well-established prostheses, much remains to be understood about how these implants wear in use. This important book summarises the wealth of recent research in this area and its implications for implant and joint design.
After an introductory overview, the book reviews the causes and prevention of implant wear. Part one discusses fundamental issues such as tissue response to wear, the anatomy and biomechanics of hips and knees as well as the materials and design issues they raise for hip, knee and other types of orthopaedic implant. Part two considers wear phenomena in a range of materials, including ultra-high molecular weight (UHMWPE), metal and ceramic joints. It also covers surgical and other factors influencing wear as well as ways of detecting, analysing and predicting implant wear and failure.
With its distinguished editor and international team of contributors, Wear of orthopaedic implants and artificial joints is a standard reference for implant manufacturers, surgeons and those researching this important area.
Summarises the wealth of recent research into the wear of orthopaedic implants and artificial joints and discusses the implications for implant and joint designReviews the causes and prevention of implant wear, tissue response to wear, the anatomy and biomechanics of hips and knees and the materials and design issues they raise for orthopaedic implantsConsiders wear phenomena in a range of materials, including ultra-high molecular weight (UHMWPE), metal and ceramic joints

Developments in tissue engineered and regenerative medicine products summarizes recent developments in tissue engineering and regenerative medicine with an emphasis on commercialization and product development. Features of current cell therapy and tissue engineered products which have facilitated successful commercialization are emphasized and roadblocks to successful product development are also highlighted. Preclinical and clinical testing of tissue engineered and regenerative medicine products, regulatory, quality control, manufacturing issues, as well as generating and securing intellectual property and freedom to operate considerations are presented. This book represents a complete 'how-to' manual for the development of tissue engineered and regenerative medicine products from conceptualization to clinical trial to manufacturing.
Addresses practical considerations for the field of tissue engineering and regenerative medicine from the perspective of the biotechnology industryWritten as a manual for tissue engineering and regenerative medicine product development applicable to the US and EUIllustrates pathway integration of science and business required for successful product development