Systems biology came about as growing numbers of engineers and scientists from other fields created algorithms which supported the analysis of biological data in incredible quantities. Whereas biologists of the past had been forced to study one item or aspect at a time, due to technical and biological limitations, it suddenly became possible to study biological phenomena within their natural contexts. This interdisciplinary field offers a holistic approach to interpreting these processes, and has been responsible for some of the most important developments in the science of human health and environmental sustainability. This Very Short Introduction outlines the exciting processes and possibilities in the new field of systems biology. Eberhard O. Voit describes how it enabled us to learn how intricately the expression of every gene is controlled, how signaling systems keep organisms running smoothly, and how complicated even the simplest cells are. He explores what this field is about, why it is needed, and how it will affect our understanding of life, particularly in the areas of personalized medicine, drug development, food and energy production, and sustainable stewardship of our environments. Throughout he considers how new tools are being provided from the fields of mathematics, computer science, engineering, physics, and chemistry to grasp the complexity of the countless interacting processes in cells which would overwhelm the cognitive and analytical capabilities of the human mind. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

This book critically examines how mathematical modelling shapes and limits a scientific approach to the natural world and affects how society views nature. It questions concepts such as determinism, reversibility, equilibrium, and the isolated system, and challenges the view of physical reality as passive and inert. Dan Bruiger argues that if nature is real, it must transcend human representations. In particular, it can be expected to self-organize in ways that elude a mechanist treatment. This interdisciplinary study addresses several key areas: the "crisis" in modern physics and cosmology; the limits and historical, psychological, and religious roots of mechanistic thought; and the mutual effects of the scientific worldview upon society's relationship to nature. Bruiger demonstrates that there is still little place outside biology for systems that actively self-organize or self-define. Instead of appealing to "multiverses" to resolve the mysteries of fine-tuning, he suggests that cosmologists look toward self-organizing processes. He also states that physics is hampered by its external focus and should become more self-reflective. If scientific understanding can go beyond a stance of prediction and control, it could lead to a relationship with nature more amenable to survival. The Found and the Made fills a void between popular science writing and philosophy. It will appeal to naturalists, environmentalists, science buffs, professionals, and students of cultural history, evolutionary psychology, gender studies, and philosophy of mind.

This stunningly illustrated book provides a rare window into the amazing, varied, and often beautiful world of viruses. Contrary to popular belief, not all viruses are bad for you. In fact, several are beneficial to their hosts, and many are crucial to the health of our planet. Virus offers an unprecedented look at 101 incredible microbes that infect all branches of life on Earth--from humans and other animals to insects, plants, fungi, and bacteria. Featuring hundreds of breathtaking color images throughout, this guide begins with a lively and informative introduction to virology. Here readers can learn about the history of this unique science, how viruses are named, how their genes work, how they copy and package themselves, how they interact with their hosts, how immune systems counteract viruses, and how viruses travel from host to host. The concise entries that follow highlight important or interesting facts about each virus. Learn about the geographic origins of dengue and why old tires and unused pots help the virus to spread. Read about Ebola, Zika, West Nile, Frog virus 3, the Tulip breaking virus, and many others--how they were discovered, what their hosts are, how they are transmitted, whether or not there is a vaccine, and much more. Each entry is easy to read and includes a graphic of the virus, and nearly every entry features a colorized image of the virus as seen through the microscope. Written by a leading authority, this handsomely illustrated guide reveals the unseen wonders of the microbial world. It will give you an entirely new appreciation for viruses.

This book offers a largely chronological illustrated guide to how the chemical elements were discovered over the past three millennia. It provides a view not just of how we came to understand what everything is made of but also of how chemistry developed from a trial-and-error craft of making and transforming substances into a rational modern science that provides us with new materials, drugs, and much else. While other books have described the properties of the chemical elements and often delved into their histories, none has done so in this highly visual manner. The closest comparison is Theodore Gray's illustrated book The Elements - but this does not take a historical approach as this does here. The pictorial material for this subject is very rich, including some gorgeous alchemical documents as well as portraits, colour charts, woodcuts of mining, artefacts such as John Dalton's wooden balls, advertisements (for example, for radium 'cures') and postage stamps. The book contains separate short sections for each element or groups of related elements, which are gathered into several sections to order the sequence into several chronological eras of element discovery. Included are short 'interludes' (or 'feature spreads') presenting important intellectual milestones in how we think about elements. With 192 illustrations

Faszination Satellitennavigation – welche Rolle spielt sie im täglichen Leben? Wie funktioniert diese Technik? Was wäre, wenn GPS abgeschaltet würde? Und wie steht es um das europäische Galileo-System?In den vergangenen 20 Jahren hat sich die Satellitennavigation von einer anfangs rein militärischen Technologie hin zur vollkommen selbstverständlich genutzten Alltagstechnik entwickelt. Die Bandbreite reicht vom Navigationsgerät im Auto über Smartphones und kleine Empfänger für Outdoorsportler bis hin zu hochgenauen Spezialgeräten zum Zwecke der Landvermessung. Der Autor erläutert die im Prinzip sehr einfache Funktionsweise, welche jedoch in der konkreten Umsetzung modernste Methoden der Nachrichten- und Elektrotechnik, der Geographie und der Physik erfordert.  In der zweiten Auflage wird verstärkt auf das europäische Galileo-System eingegangen und dessen aktueller Ausbaustand beschrieben.

How to make it, break it, hack it, crack it. The secret history of codes and code breaking. Simon Singh's best-selling title The Code Book now re-issued for the young-adult market. The Science of Secrecy from Ancient Egypt to Quantum Cryptography. Simon Singh brings life to an amazing story of puzzles, codes, languages and riddles -- revealing the continual pursuit to disguise and uncover, and to work out the secret languages of others. Codes have influenced events throughout history, both in the stories of those who make them and those who break them. The betrayal of Mary Queen of Scots and the cracking of the enigma code that helped the Allies in World War II are major episodes in a continuing history of cryptography. In addition to stories of intrigue and warfare, Simon Singh also investigates other codes, the unravelling of genes and the rediscovery of ancient languages and most tantalisingly, the Beale ciphers, an unbroken code that could hold the key to a USD20 million treasure.

Can we give Grandma a Viking funeral? Why don't animals dig up all the graves? Will my hair keep growing in my coffin after I'm buried? Every day, funeral director Caitlin Doughty receives dozens of questions about death. Here she offers her factual, hilarious and candid answers to thirty-five of the most interesting, sharing the lore and science of what happens to, and inside, our bodies after we die. Why do corpses groan? What causes bodies to turn strange colours during decomposition? and why do hair and nails appear longer after death? The answers are all within . . .

Why the social character of scientific knowledge makes it trustworthy Are doctors right when they tell us vaccines are safe? Should we take climate experts at their word when they warn us about the perils of global warming? Why should we trust science when so many of our political leaders don't? Naomi Oreskes offers a bold and compelling defense of science, revealing why the social character of scientific knowledge is its greatest strength-and the greatest reason we can trust it. Tracing the history and philosophy of science from the late nineteenth century to today, this timely and provocative book features a new preface by Oreskes and critical responses by climate experts Ottmar Edenhofer and Martin Kowarsch, political scientist Jon Krosnick, philosopher of science Marc Lange, and science historian Susan Lindee, as well as a foreword by political theorist Stephen Macedo.

A rich and wonderful history of quinine - the cure for malaria. In the summer of 1623, ten cardinals and hundreds of their attendants, engaged in electing a new Pope, died from the 'mal'aria' or 'bad air' of the Roman marshes. Their choice, Pope Urban VIII, determined that a cure should be found for the fever that was the scourge of the Mediterranean, northern Europe and America, and in 1631 a young Jesuit apothecarist in Peru sent to the Old World a cure that had been found in the New - where the disease was unknown. The cure was quinine, an alkaloid made of the bitter red bark of the cinchona tree, which grows in the Andes. Both disease and cure have an extraordinary history. Malaria badly weakened the Roman Empire. It killed thousands of British troops fighting Napoleon during the Walcheren raid on Holland in 1809 and many soldiers on both sides of the American Civil War. It turned back many of the travellers who explored west Africa and brought the building of the Panama Canal to a standstill. When, after a thousand years, a cure was finally found, Europe's Protestants, among them Oliver Cromwell, who suffered badly from malaria, feared it was nothing more than a Popish poison. More than any previous medicine, though, quinine forced physicians to change their ideas about treating illness. Before long, it would change the face of Western medicine. Using fresh research from the Vatican and the Indian Archives in Seville, as well as hitherto undiscovered documents in Peru, Fiammetta Rocco describes the ravages of the disease, the quest of the three Englishmen who smuggled cinchona seeds out of South America, the way quinine opened the door to Western imperial adventure in Asia, Africa and beyond, and why, even today, quinine grown in the eastern Congo still saves so many people suffering from malaria.

Twenty years after Stephen Hawking's 9-million-copy selling A Brief History of Time, pioneering theoretical physicist Sean Carroll takes our investigation into the nature of time to the next level. You can't unscramble an egg and you can't remember the future. But what if time doesn't (or didn't!) always go in the same direction? Carroll's paradigm-shifting research suggests that other universes experience time running in the opposite direction to our own. Exploring subjects from entropy and quantum mechanics to time travel and the meaning of life, Carroll presents a dazzling new view of how we came to exist.

Look up... The Art of Stargazing is the ultimate insider's guide to the night sky in which award-winning space scientist and The Sky at Night presenter Dr Maggie Aderin-Pocock shares her expertise and unique insights into the marvellous world of stars. Take a tour of the 88 constellations and explore the science, history, culture and romanticism behind these celestial bodies. In this must-have handbook for budding stargazers - and anyone looking for a little more wonder in their lives - Maggie will help you to identify stars and teach you the basics of naked-eye observation, offering fascinating facts plus advice on kit, 'dark sky' locations and much more. Also included are beautiful illustrations to accompany each constellation and an easy-to-read sky map. With Maggie by your side, the night sky will truly come alive.

Since the earliest humans walked the earth, the vast mysteries and wonders of the night sky have fascinated and beguiled us, as we’ve struggled to understand our place in the cosmos. Even after the last century, which saw important and startling discoveries about our own planet, our solar system and the stars and galaxies beyond, there remain more questions than answers. But those questions – What is dark matter? Are we alone in the universe? Is time travel possible? – provide a fascinating insight into the vastness and infinite possibilities of space that we’re yet to determine. The sheer scale of the universe can be intimidating, but in this easily digestible book we embark on an incredible journey through all the essential astronomical discoveries, from the beliefs of ancient civilizations, through to the recent groundbreaking observations of the gravitational waves predicted by Einstein over 100 years ago. There’s never been a better time to get to grips with the universe and this essential guide to the cosmos is the perfect place to start!

This book sheds light on a little-known aspect of the Imperial family of Japan: For three generations, members of the family have devoted themselves to biological research. Emperor Showa (Hirohito) was an expert on hydrozoans and slime molds. His son, Emperor Akihito, is an ichthyologist specializing in gobioid fishes, and his research is highly respected in the field. Prince Akishino, Emperor Akihito's son, is known for his research on giant catfish and the domestication of fowl, while Prince Hitachi, Emperor Akihito's brother, has conducted research on cancer in animals. The book shows how they became interested in biology, how seriously they were committed to their research, what their main scientific contributions are, and how their achievements are valued by experts at home and abroad. To commemorate the 60-year reign of Emperor Showa and his longtime devotion to biology, the International Prize for Biology was founded in 1985. The prize seeks to recognize and encourage researches in basic biology. A list of winners and a summary of their research are presented in the last part of the book. The author, an eminent biologist who has given lectures to the Imperial Family, explains their research and tells the fascinating story of biology and the Imperial Family of Japan. The book is a valuable resource, not only for biology students and researchers, but also for historians and anyone interested in science and the Royal and Imperial families.

If you want beautiful, healthy, glowing skin, whatever your age, then look no further. This Scandinavian bestseller will revolutionise how you care for your body's largest organ. What does the latest research tell us about our skin? How do our hormones, genetics, diet, and environment play a part? What should we look for in our beauty products, and what should we avoid? In this comprehensive guide, skin scientist Johanna Gillbro teaches you how best to care for your skin - and what not to do. Think drinking water will replenish your skin? Think again. More products, better skin? Nope. And an expensive product doesn't guarantee reliable results. You don't need to cleanse your skin in the morning; in fact, too much cleansing can be damaging. Toner is redundant, natural products are not always best, and bacteria are not the enemy - and that's just the start! Learn how to read the labels on products, know exactly what it is you're putting on your skin, and make better decisions about how you care for it. Using cutting-edge research about the microbiome, as well as the relationship between gut health and skin, The Scandinavian Skincare Bible challenges how we look at beauty today. By revealing the science and exposing commercial tricks, Dr Gillbro empowers us to lay the foundation for healthy, beautiful skin.

Recent scientific discoveries indicate that all of life – from the most primitive cells, up to human societies, corporations and nation-states, even the global economy – is organized along the same basic patterns and principles: those of the network.

However, the new global economy differs in important aspects from the networks of life: whereas everything in a living network has a function, globalism ignores all that cannot give it an immediate profit, creating great armies of the excluded. The global financial network also relies on advanced information technologies – it is shaped by machines, and the resulting economic, social and cultural environment is not life-enhancing but life-degrading, in both a social and an ecological sense.

Capra demonstrates conclusively how tightly humans are connected with the fabric of life and makes it clear that it is imperative to organize the world according to a different set of values and beliefs, not only for the well-being of human organizations, but for the survival and sustainability of humanity as a whole.

The "New York Times "bestselling "manifesto for the future that is grounded in practical solutions addressing the world's most pressing concerns: overpopulation, food, water, energy, education, health care and freedom" ("The Wall Street Journal").
Since the dawn of humanity, a privileged few have lived in stark contrast to the hardscrabble majority. Conventional wisdom says this gap cannot be closed. But it is closing--fast.
In "Abundance," space entrepreneur turned innovation pioneer Peter H. Diamandis and award-winning science writer Steven Kotler document how progress in artificial intelligence, robotics, digital manufacturing synthetic biology, and other exponentially growing technologies will enable us to make greater gains in the next two decades than we have in the previous 200 years. We will soon have the ability to meet and exceed the basic needs of every person on the planet. Abundance for all is within our grasp.
Breaking down human needs by category--water, food, energy, healthcare, education, freedom--Diamandis and Kotler introduce us to innovators and industry captains making tremendous strides in each area. "Not only is "Abundance" a riveting page-turner...but it's a book that gives us a future worth fighting for. And even more than that, it shows us our place in that fight" ("The Christian Science Monitor").

"A remarkable addition to the literature of the science of the mind…Shenk has drawn together neurobiology, art history and psychology into a literary portrait of Alzheimer's perfectly balanced between sorrow and wonder, devastation and awe."
'LA Times'

Jonathan Swift once pointed to a diseased elm and declared 'I shall be like that tree, I shall die first at the top'. And, as our lifespans continue to expand, the illness he so dreaded has reached epidemic proportions. Today Alzheimer's afflicts on in twenty over the age of sixty-five. There are currently around twelve million sufferers worldwide, and this number is rising fast. Poignant and hopeful, 'The Forgetting' is the first book to record the history and explain the future of this difficult, frightening disease.

"[An] absorbing and enlightening book…and an engrossing story."
'TLS'

"A lucid, often moving book with an excellent preface from Adam Phillips…Shenk is a wonderful writer…His prose zings with apt metaphors. He has an eye for the social and financial forces that shape scientific interests and he brings key players, whether proteins or people, to dramatic life."
'Independent'

"'The Forgetting' is completely absorbing, fascinating, the best of writing, thought-provoking, socially important and imperative to read – with the narrative pull of a well-written murder mystery."
AMY TAN, author of 'The Bonesetter's Daughter'

This text reveals research that has transformed scientists' understanding of healthy ageing and shows what everyone can do to help prevent Alzheimer's disease. One of the world's leading experts on Alzheimer's disease, David Snowdon, is the director of the "Nun Study", a long term research project involving 678 nuns. Ranging in age from 75 to 106, these women have allowed Snowdon access to their medical and personal records and they have agreed to donate their brains upon death. The study's findings are already helping scientists unlock the secrets to living a longer, healthier life. With one of the largest brain donor studies in the world, Dr Snowdon and his colleagues are at the forefront of some of the most fascinating and useful research on aging today. This book combines cutting-edge research on the brain with the poignant and inspiring stories of the ageing nuns who are teaching scientists how we grow old. We meet nuns like Sister Clarissa, who at the age of 90 drives around the convent in a motorized cart she calls her "Chevy" and knows as much about baseball as any die-hard fan a third her age, and "The Magnificent Seven", centenarians from a single convent who remain activ

'A book that would have had Darwin swooning - anyone seriously interested in who we are and how we function should read this.' Guardian At the beginning of this century enormous progress had been made in genetics. The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

Throughout history, from the Ancient Egyptians to medieval saints and the remains of figures like Eva Peron and Lenin, mummies have held a powerful place in our collective imagination. THE MUMMY CONGRESS is a riveting survey of the history, science and popular culture of mummies and of man's ancient quest for immortality. When acclaimed science journalist Heather Pringle was dispatched to a remote part of northern Chile to cover a little-known scientific conference, she found herself in the midst of the most passionate gathering of her working life - dozens of mummy experts crammed into a rambling seaside hotel, battling over the implications of their latest discoveries. Infected with their mania, Pringle spent the next year circling the globe, stopping in to visit the leading scientists so she could see first-hand the breathtaking delicacy and unexpected importance of their work. In The Mummy Congress, she recounts the intriguing findings from her travels, bringing to life the hitherto unknown worlds of the long-dead, and revealing what mummies have to tell us about ourselves. Pringle's journeys lead her to the lifelike remains of medieval saints entombed in Italy's grand cathedrals, eerily preserved bog bodies in the Netherlands bearing signs of violent and untimely slaughter, and frozen Inca princesses glimpsed for the first time atop icy mountains. She learns of the extraordinary skills of ancient Egyptian embalmers capable of preserving bodies, in the words of one mummy expert, "until the end of time"; of the horrifying sacrifices made by ancient South Americans to pacify their gods; and of the weird mummified parasites preserved in the guts of millennia-old bodies and that still wreak havoc across the world today.

'Brilliant and fascinating. No one is better at making the recondite accessible and exciting' Bill Bryson Britain's most famous mathematician takes us to the edge of knowledge to show us what we cannot know. Is the universe infinite? Do we know what happened before the Big Bang? Where is human consciousness located in the brain? And are there more undiscovered particles out there, beyond the Higgs boson? In the modern world, science is king: weekly headlines proclaim the latest scientific breakthroughs and numerous mathematical problems, once indecipherable, have now been solved. But are there limits to what we can discover about our physical universe? In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data. Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding? In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there's anything we truly cannot know.

Is there life on Mars? If not, why not? These questions have gripped mankind throughout the twentieth century. In the shadow of the new millennium, The Genesis Question seeks the definitive answers from the scientists participating in the race to discover life on the Red Planet. 'Ever since I was a small child, I've believed there was life out there. When I look at the magnitude of the universe, with its billions of stars, I believe that if life developed here on Earth, it must have developed elsewhere. We simply can't be unique. I really don't think we're the most intelligent life forms in the universe, but that's just my gut feeling', Dr Claire Parkinson, NASA scientist. Of all the planets, Mars has exerted the most powerful allure over the human intellect and imagination. Generations of astronomers have expected to find clues to the origin and destiny of Earth and its inhabitants concealed amid the red storms sweeping across the surface of Mars. Today, public interest in the Mars mission is sky-high; the exploits of the tiny Mars Rover 'Sojourner' in the summer of 1997 excited the greatest curiosity in a space mission in a generation. In The Quest for Mars Laurence Bergreen has unrestricted access to a team of NASA employees - engineers, geologists and other scientists - who are consumed by the search for proof of life on Mars. As one formidable obstacle after another attempts to scupper their quest for a deeper understanding of life on Mars and throughout the Solar System, the narrative takes us step by step through the exhilaration and the despondency of their extraordinary adventure. Nothing is off limits in this unique, behind-the-scenes story of space exploration.

A revealing and entertaining guide through some of the biggest misconceptions in science that many of us still believe. You may well be familiar with the fact that lightning, contrary to the popular saying, often strikes the same place twice. But this is just the tip of the iceberg when it comes to what many of us wrongly believe about the way the world works. Whether it's word of mouth, myths you've read about online, or misremembered facts from school, we're bombarded by misconceptions about the science we come into contact with every day - this book will uncover the most popular myths to help you avoid contributing to the perpetuation of these misunderstandings. Breaking it down into fifty of the most popular misconceptions in science, each chapter of this book will be headed up with a 'fact', followed by the real story, providing the science and theory that debunks the myth. From fears about the exponential growth of the human population to the embarrassment of always pointing out the north star as the brightest in the sky, this is the book to read if you want to separate the science fact from fiction.

The latest volume in The New York Times bestselling physics series explains Einstein's masterpiece- the general theory of relativity He taught us classical mechanics, quantum mechanics and special relativity. Now, physicist Leonard Susskind, assisted by a new collaborator, Andre Cabannes, returns to tackle Einstein's general theory of relativity. Starting from the equivalence principle and covering the necessary mathematics of Riemannian spaces and tensor calculus, Susskind and Cabannes explain the link between gravity and geometry. They delve into black holes, establish Einstein field equations and solve them to describe gravity waves. The authors provide vivid explanations that, to borrow a phrase from Einstein himself, are as simple as possible (but no simpler). An approachable yet rigorous introduction to one of the most important topics in physics, General Relativity is a must-read for anyone who wants a deeper knowledge of the universe's real structure.

Who are we? Where is the boundary between us and everything else? Are we all multiple personalities? And how can we control who we become? From distinguished psychologist Robert Levine comes this provocative and entertaining scientific exploration of the most personal and important of all landscapes: the physical and psychological entity we call our self. Using a combination of case studies and cutting-edge research in psychology, biology, neuroscience, virtual reality and many other fields, Levine challenges cherished beliefs about the unity and stability of the self - but also suggests that we are more capable of change than we know. Transformation, Levine shows, is the human condition at virtually every level. Physically, our cells are unrecognizable from one moment to the next. Cognitively, our self-perceptions are equally changeable: A single glitch can make us lose track of a body part or our entire body, or to confuse our very self with that of another person. Psychologically, we switch back and forth like quicksilver between incongruent, sometimes adversarial sub-selves. Socially, we appear to be little more than an ever-changing troupe of actors. And, culturally, the boundaries of the self vary wildly around the world - from the confines of one's body to an entire village. The self, in short, is a fiction: vague, arbitrary, and utterly intangible. But it is also interminably fluid. And this unleashes a world of potential. Engaging, informative, and ultimately liberating, Stranger in the Mirror will change forever how you think about your self - and what you might become.