Silas Burroughs arrived in London from America in 1878 and proved himself an exceptional entrepreneur, taking the pharmaceutical business by storm. He was the brains and energy behind Burroughs Wellcome & Co. With his business partner Henry Wellcome he created an internationally successful firm, the legacy of which can be found in the charity the Wellcome Trust, yet few now remember him and the impact he made in his short lifetime. A consummate salesman, Burroughs was also an astute businessman, with new ideas for marketing, advertising and manufacturing: his writings describe sales trips around the world and the people he met. He was also a visionary employer who supported the eight-hour working day, profit-sharing, and numerous social and radical political movements, including the single tax movement, free travel, Irish Home Rule and world peace. In this first biography of Burroughs, Julia Sheppard explores his American origins, his religion and marriage, and his philanthropic work, as well as re-evaluating the dramatic deterioration of his relationship with his partner Wellcome.

This book explains how the Apollo crews learned to work on the lunar surface. Its lively and informative text draws heavily on transcripts and photographs to illustrate points. It puts the reader on the lunar surface with the astronauts, sharing their observations, excitement, and frustrations. The book describes the challenging yet exhilarating lunar environment facing the Apollo astronauts, and reveals their courageous, sometimes creative and occasionally humorous adaptation to the field conditions on another planet. Recent interviews with the astronauts are included in which they recall their thoughts after more than 25 years of reflection.

This revised and greatly expanded second edition of the Russian text contains a wealth of new information about the lives and accomplishments of more than a dozen scientists throughout five centuries of history: from the first steps in algebra up to new achievements in geometry in connection with physics. The heroes of the book are renowned figures from early eras, as well some scientists of last century. A unique mixture of mathematics, physics, and history, this volume provides biographical glimpses of scientists and their contributions in the context of the social and political background of their times.

James T. Costa takes readers on a journey from Charles Darwin's youth and travels on the HMS Beagle to Down House, his bustling home of forty years. To test his insights into evolution, Darwin devised experiments using his garden and greenhouse, the surrounding land and his home-turned-field-station. His experiments yielded universal truths about nature and evidence for his revolutionary arguments in On the Origin of Species and other watershed works. We accompany Darwin in his myriad pursuits against the backdrop of his enduring marriage, chronic illness, grief at the loss of three children and joy in scientific revelation. At each chapter's end, Costa shows how we can investigate the wonders of nature, with directions on how to re-create Darwin's experiments.

Many people know that Albert Einstein was a brilliant theoretical physicist who revolutionised modern science. What they may not know is that he only learnt to speak at four years old; that he was asked to become the President of Israel in 1952, but refused; or that he was under FBI surveillance for 22 years. This book presents an instant impression of his life with 50 irresistible facts converted into infographics to reveal the scientist behind the science.

Many people know that Tesla was a scientific genius, instrumental in developing modern electricity and communications. What, perhaps, they don't know is that he was born during a lightning storm; spoke eight languages; and claimed to have invented a death ray that could destroy 10,000 planes from 250 miles away. This book presents an electrifying exploration of his life, work and fame, with 50 irresistible facts converted into infographics to reveal the scientist behind the science.

In May 1961, President Kennedy announced that the United States would attempt to land a man on the moon and return him safely to the earth before the end of that decade. Yet NASA did not have a specific plan for how to accomplish that goal. Over the next fourteen months, NASA vigorously debated several options. At first the consensus was to send one big rocket with several astronauts to the moon, land and explore, and then take off and return the astronauts to earth in the same vehicle. Another idea involved launching several smaller Saturn V rockets into the earth orbit, where a lander would be assembled and fueled before sending the crew to the moon. But it was a small group of engineers led by John C. Houbolt who came up with the plan that propelled human beings to the moon and back-not only safely, but faster, cheaper, and more reliably. Houbolt and his colleagues called it "lunar orbit rendezvous," or "LOR." At first the LOR idea was ignored, then it was criticized, and then finally dismissed by many senior NASA officials. Nevertheless, the group, under Houbolt's leadership, continued to press the LOR idea, arguing that it was the only way to get men to the moon and back by President Kennedy's deadline. Houbolt persisted, risking his career in the face of overwhelming opposition. This is the story of how John Houbolt convinced NASA to adopt the plan that made history.

This book recounts the life and achievements of Clarence King, widely recognized as one of America's most gifted intellectuals of the nineteenth century, and a legendary figure in the American West. King's genius, singular accomplishments, and near-death adventures unfold in a narrative centered on his personal relationship with his lifelong friend and colleague, James Gardner. The two, upon completing their studies at Yale, traveled by wagon train across the continent and worked with the California Geological Survey. King went on to establish the Geological Exploration of the 40th Parallel, a government mapping program that stretched across the western mountain chains from California to Wyoming. This was the precursor to the U.S. Geological Survey (USGS). Founded in 1879, with Clarence King as its architect and first director, the USGS became the most important and influential science agency in the nation. The adventurous aspects of conducting geological fieldwork in the West, much of them documented by letters written by King and Gardner, punctuate a book copiously illustrated with historic maps and photographs showing localities and people important to the story.

Families are riddled with untold secrets. But Stephen Hinshaw never imagined that a profound secret was kept under lock and key for 18 years within his family - that his father's mysterious absences, for months at a time, resulted from serious mental illness and involuntary hospitalisations. From the moment his father revealed the truth, during Hinshaw's first spring break from college, he knew his life would change forever. Hinshaw calls this revelation his 'psychological birth.' After years of experiencing the ups and downs of his father's illness without knowing it existed, Hinshaw began to piece together the silent, often terrifying history of his father's life - in great contrast to his father's presence and love during periods of wellness. This exploration led to larger discoveries about the family saga, to Hinshaw's correctly diagnosing his father with bipolar disorder, and to his full-fledged career as a clinical and developmental psychologist and professor. In Another Kind of Madness, Hinshaw explores the burden of living in a family 'loaded' with mental illness and debunks the stigma behind it. He explains that in today's society, mental health problems still receive utter castigation - too often resulting in the loss of fundamental rights, including the inability to vote or run for office or automatic relinquishment of child custody. Through a poignant and moving family narrative, interlaced with shocking facts about how America and the world still view mental health conditions well into in the 21st century, Another Kind of Madness is a passionate call to arms regarding the importance of destigmatising mental illness.

From New York Times bestselling author and blogger Heather B. Armstrong comes an honest and irreverent memoir--reminiscent of the New York Times bestseller Brain on Fire--about her experience as the third person ever to participate in an experimental treatment for depression involving ten rounds of a chemically induced coma approximating brain death. For years, Heather B. Armstrong has alluded to her struggle with depression on her website, dooce. It's scattered throughout her archive, where it weaves its way through posts about pop culture, music, and motherhood. In 2016, Heather found herself in the depths of a depression she just couldn't shake, an episode darker and longer than anything she had previously experienced. She had never felt so discouraged by the thought of waking up in the morning, and it threatened to destroy her life. For the sake of herself and her family, Heather decided to risk it all by participating in an experimental clinical trial. Now, for the first time, Heather recalls the torturous eighteen months of suicidal depression she endured and the month-long experimental study in which doctors used propofol anesthesia to quiet all brain activity for a full fifteen minutes before bringing her back from a flatline. Ten times. The experience wasn't easy. Not for Heather or her family. But a switch was flipped, and Heather hasn't experienced a single moment of suicidal depression since. "Breathtakingly honest" (Lisa Genova, New York Times bestselling author), self-deprecating, and scientifically fascinating, The Valedictorian of Being Dead brings to light a groundbreaking new treatment for depression. The Valedictorian of Being Dead was previously published with the subtitle "The True Story of Dying Ten Times to Live."

James Tobin, award-winning author of "Ernie Pyle's War" and "The Man He Became," has penned the definitive account of the inspiring and impassioned race between the Wright brothers and their primary rival Samuel Langley across ten years and two continents to conquer the air.
For years, Wilbur Wright and his younger brother, Orville, experimented in obscurity, supported only by their exceptional family. Meanwhile, the world watched as Samuel Langley, armed with a contract from the US War Department and all the resources of the Smithsonian Institution, sought to create the first manned flying machine. But while Langley saw flight as a problem of power, the Wrights saw a problem of balance. Thus their machines took two very different paths--Langley's toward oblivion, the Wrights' toward the heavens--though not before facing countless other obstacles. With a historian's accuracy and a novelist's eye, Tobin has captured an extraordinary moment in history. "To Conquer the Air" is itself a heroic achievement.

Praise for "The Lobotomist"

"Written with such clarity and engaging detail that a reader has difficulty in putting it down."
--"The New York Review of Books"

"One of the many virtues of El-Hai's text is the rich detail he provides about Freeman's life and ideas."
--"Los Angeles Times"

"Fascinating . . . an important and disturbing contribution to the history of psychiatry."
--"New Statesman"

"Captivating. . . . No history of modern psychiatry is complete without this story."
--Andrew Solomon, author of "The Noonday Demon"

"The Lobotomist" explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the twentieth century. Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Although many patients did not benefit from the thousands of lobotomies Freeman performed, others believed their lobotomies changed them for the better.

Drawing on a rich collection of documents Freeman left behind and interviews with Freeman's family, Jack El-Hai takes a penetrating look into the life of this complex scientific genius and traces the physician's fascinating life and work.

When the world stopped, all hopes rested on finding a vaccine. One team answered the call and were ready to act. But how do you develop a life-saving drug when every second counts and one mistake could be catastrophic?

Married couple and decades-long research partners Ugur Sahin and Özlem Türeci did just that within weeks of the pandemic breaking out. From convincing Big Pharma to support their ambitious project, to navigating political interference from the Trump administration and the European Union, the road to producing the Pfizer/BioNTech vaccine was by no means smooth. But these cutting-edge innovators overcame every obstacle to provide more than two billion doses of the life-saving drug to countries all around the world in record time.

The Vaccine draws back the curtain on one of the most important medical breakthroughs of our age, containing contributions from the fascinating couple themselves, as well as more than 50 scientists, politicians, public health officials, and BioNTech staff.

Shedding a light on the science behind the breakthrough, The Vaccine tells the story of the trailblazers to whom we all owe a debt of gratitude. More suspenseful than a novel, this is a real-life story of an extraordinary race against time to save the world.

300 years ago, in April 1721, a smallpox epidemic was raging in England. Lady Mary Wortley Montagu knew that she could save her 3-year-old daughter using the process of inoculation. She had witnessed this at first hand in Turkey, while she was living there as the wife of the British ambassador. She also knew that by inoculating - making her daughter the first person protected in the West - she would face opposition from doctors, politicians and clerics. Her courageous action eventually led to the eradication of smallpox and the prevention of millions of deaths. But Mary was more than a scientific campaigner. She mixed with the greatest politicians, writers, artists and thinkers of her day. She was also an important early feminist, writing powerfully and provocatively about the position of women. She was best friends with the poet Alexander Pope. They collaborated on a series of poems, which made her into a household name, an 'It Girl'. But their friendship turned sour and he used his pen to vilify her publicly. Aristocratic by birth, Mary chose to elope with Edward Wortley Montagu, whom she knew she did not love, so as to avoid being forced into marrying someone else. In middle age, her marriage stale, she fell for someone young enough to be her son - and, unknown to her, bisexual. She set off on a new life with him abroad. When this relationship failed, she stayed on in Europe, narrowly escaping the coercive control of an Italian conman. After twenty-two years abroad, she returned home to London to die. The son-in-law she had dismissed as a young man had meanwhile become Prime Minister.

Long Road from Quito presents a fascinating portrait of David Gaus, an unlikely trailblazer with deep ties to the University of Notre Dame and an even more compelling postgraduate life. Gaus is co-founder, with his mentor Rev. Theodore M. Hesburgh, C.S.C., of Andean Health and Development (AHD), an organization dedicated to supporting health initiatives in South America. Tony Hiss traces the trajectory of Gaus's life from an accounting undergraduate to a medical doctor committed to bringing modern medicine to poor, rural communities in Ecuador. When he began his medical practice in 1996, the best strategy in these areas consisted of providing preventive measures combined with rudimentary clinical services. Gaus, however, realized he had to take on a much more sweeping approach to best serve sick people in the countryside, who would have to take a five-hour truck ride to Quito and the nearest hospital. He decided to bring the hospital to the patients. He has now done so twice, building two top-of-the-line hospitals in Pedro Vicente Maldonado and Santo Domingo, Ecuador. The hospitals, staffed only by Ecuadorians, train local doctors through a Family Medicine residency program, and are financially self-sustaining. His work with AHD is recognized as a model for the rest of Latin America, and AHD has grown into a major player in global health, frequently partnering with the World Health Organization and other international agencies. With a charming, conversational style that is a pleasure to read, Hiss shows how Gaus's vision and determination led to these accomplishments, in a story with equal parts interest for Notre Dame readers, health practitioners, medical anthropologists, Latin American students and scholars, and the general public.

Subrahmanyan Chandrasekhar, Nobel Laureate in Physics, was a towering figure in 20th century physics, but remained a highly private man. The many letters and correspondence in this book reveal in Chandrasekhar's own words the depth of his pursuit of science as well as his personal struggles. This book is an important addition to the three previous volumes by Kameshwar C. Wali, including Chandra, A Biography of S. Chandrasekhar, S. Chandrasekhar: The Man Behind the Legend, and A Quest for Perspectives: Selected Works of S. Chandrasekhar (With Commentary), Volumes 1 & 2.Included in the correspondence are Chandra's thoughts and feelings about his student days in India and Cambridge, his trials and tribulations in the competitive world of British academia, his travels to Russia and Germany, and his unexpected and historic encounter with Sir Arthur Eddington. The book also includes rare correspondence and conversations with Lalitha, Chandrasekhar's wife of over sixty years. The letters and conversations with her reflect her own views of their life. She, a student of physics herself, eventually gave up her own work in science to become an integral part of Chandra's life. As Chandra wrote, 'The full measure of [of my indebtedness] cannot really be recorded; it is too deep and too all persuasive. Let me then record simply that Lalitha was the motivating source and strength of my life.'This new book adds a significant personal dimension to an extraordinary scientist and will give the public a deeper understanding of the man behind the legend.

The Beginner Books -- "Their cartoon format and irreverent wit make difficult ideas accessible and entertaining."

-- Newsday

aking us through the upheavals in biological thought which made The Origins of Species possible, Jonathan Miller introduces us to that odd revolutionary, Charles Darwin -- a remarkably timid man who spent most of his life in seclusion; a semi-invalid riddled with doubts, fearing the controversy his theories might unleash; yet also the man who finally undermined belief in God's creation. Along the way we meet a fascinating cast of characters: Darwin's scientific predecessors, his contemporaries (including Alfred Russell Wallace, whose anticipation of natural selection forced Darwin to publish), his opponents, and his successors whose work in modern genetics provided necessary modifications to Darwin's own work.

Splendidly illustrated, this clever, witty, highly informative book is the perfect introduction to Darwin's life and thought.

When Charles Darwin, then age 22, first saw the HMS Beagle, he thought it looked "more like a wreck than a vessel commissioned to go round the world." But travel around the world it did, taking Darwin to South America, Australia, New Zealand, Tahiti, and of course the Galapagos Islands, in a journey of discovery that lasted almost five years. Now, in Fossils, Finches and Fuegians, Richard Keynes, Darwin's great grandson, offers the first modern full-length account of Darwin's epoch-making expedition.

This was the great adventure of Charles Darwin's life. Indeed, it would have been a great adventure for anyone--tracking condor in Chile, surviving the great earthquake of 1835, riding across country on horseback in the company of gauchos, watching whales leaping skyward off Tierra del Fuego, hunting ostriches with a bolo, discovering prehistoric fossils and previously unknown species, and meeting primitive peoples such as the Fuegians. Keynes captures many of the natural wonders that Darwin witnessed, including an incredible swarm of butterflies a mile wide and ten miles long. Keynes also illuminates Darwin's scientific work--his important findings in geology and biology--and traces the slow revolution in Darwin's thought about species and how they might evolve. Numerous illustrations--mostly by artists who traveled with Darwin on the Beagle--grace the pages, including finely rendered drawings of many points of interest discussed in the book.

There has probably been no greater or more important scientific expedition than Darwin's voyage on the Beagle. Packed with colorful details of life aboard ship and in the wild, here is a fascinating portrait of Charles Darwin and of 19th century science.

This is the story of a boy raised up in a village in Poland during World War II, with his father deported to concentration camps throughout the war. Some years after he graduated from medical school, he serendipitously entered the then developing field of dialysis, and he eventually embarked on a career-long practice in the field, where he contributed to the development of a number of new inventions and therapeutic methods. The book contains 13 chapters covering the author's childhood, education, and his career-long contributions to the field of nephrology. The book includes inspirational stories of his patients; the struggles he faced in the course of getting his numerous inventions patented; his research work in the 1990s; his work of teaching and consulting; and not the least, his travels to interesting places unrelated to business. The book concludes with an epilogue summarizing his life, as well as his predictions regarding treatment of chronic renal failure in the future.