The forgotten garden that inspired Charles Darwin becomes the modern-day setting for an exploration of memory, family, and the legacy of genius. Darwin's childhood garden at The Mount in Shrewsbury was the site of some of the great scientist's earliest experiments. It was where, under the tutelage of his green-fingered mother and sisters, and the house's knowledgeable gardeners, he first examined the reproductive life of flowers, collected birds' eggs, and began to note down the ideas that would lead to his groundbreaking theory of evolution. In The Ghost in the Garden, Jude Piesse uncovers the lost histories that inspired Darwin's work and how his legacy, and the legacies of those around him, live on today.

A DAILY MAIL BOOK OF THE WEEK 'Spare Parts is a fascinating read filled with adventure, delight and surprise' RAHUL JANDIAL, surgeon author of 'Life on a Knife's Edge' 'This is a joyful romp through a fascinating slice of medical history' WENDY MOORE, author of 'The Knife Man' _______________________________________________________________ How did an architect help pioneer blood transfusion in the 1660s? Why did eighteenth-century dentists buy the live teeth of poor children? And what role did a sausage skin and an enamel bath play in making kidney transplants a reality? We think of transplant surgery as one of the medical wonders of the modern world. But transplant surgery is as ancient as the pyramids, with a history more surprising than we might expect. Paul Craddock takes us on a journey - from sixteenth-century skin grafting to contemporary stem cell transplants - uncovering stories of operations performed by unexpected people in unexpected places. Bringing together philosophy, science and cultural history, Spare Parts explores how transplant surgery constantly tested the boundaries between human, animal and machine, and continues to do so today. Witty, entertaining and at times delightfully macabre, Spare Parts shows us that the history - and future - of transplant surgery is tied up with questions about not only who we are, but also what we are, and what we might become. . .

An inspiring anthology of writings by trailblazing women astronomers from around the globe The Sky Is for Everyone is an internationally diverse collection of autobiographical essays by women who broke down barriers and changed the face of modern astronomy. Virginia Trimble and David Weintraub vividly describe how, before 1900, a woman who wanted to study the stars had to have a father, brother, or husband to provide entry, and how the considerable intellectual skills of women astronomers were still not enough to enable them to pry open doors of opportunity for much of the twentieth century. After decades of difficult struggles, women are closer to equality in astronomy than ever before. Trimble and Weintraub bring together the stories of the tough and determined women who flung the doors wide open. Taking readers from 1960 to today, this triumphant anthology serves as an inspiration to current and future generations of women scientists while giving voice to the history of a transformative era in astronomy. With contributions by Neta A. Bahcall, Beatriz Barbuy, Ann Merchant Boesgaard, Jocelyn Bell Burnell, Catherine Cesarsky, Poonam Chandra, Xuefei Chen, Cathie Clarke, Judith Gamora Cohen, France Anne Cordova, Anne Pyne Cowley, Bozena Czerny, Wendy L. Freedman, Yilen Gomez Maqueo Chew, Gabriela Gonzalez, Saeko S. Hayashi, Martha P. Haynes, Roberta M. Humphreys, Vicky Kalogera, Gillian Knapp, Shazrene S. Mohamed, Carole Mundell, Priyamvada Natarajan, Dara J. Norman, Hiranya Peiris, Judith Lynn Pipher, Dina Prialnik, Anneila I. Sargent, Sara Seager, Grazina Tautvaisiene, Silvia Torres-Peimbert, Virginia Trimble, Meg Urry, Ewine F. van Dishoeck, Patricia Ann Whitelock, Sidney Wolff, and Rosemary F. G. Wyse.

Unearthing the amazing hidden stories of women who changed paleontology forever. For centuries, women have played key roles in defining and developing the field of vertebrate paleontology. Yet very little is known about these important paleontologists, and the true impacts of their contributions have remained obscure. In Rebels, Scholars, Explorers, Annalisa Berta and Susan Turner celebrate the history of women "bone hunters," delving into their fascinating lives and work. At the same time, they explore how the discipline has shaped our understanding of the history of life on Earth. Berta and Turner begin by presenting readers with a review of the emergence of vertebrate paleontology as a science, emphasizing the contributions of women to research topics and employment. This is followed by brief biographical sketches and explanations of early discoveries by women around the world over the past 200 years, including those who who held roles as researchers, educators, curators, artists, and preparators. Forging new territory, Berta and Turner highlight the barriers and challenges faced by women paleontologists, describing how some managed to overcome those obstacles in order to build careers in the field. Finally, drawing on interviews with a diverse group of contemporary paleontologists, who share their experiences and offer recommendations to aspiring fossil hunters, they provide perspectives on what work still needs to be done in order to ensure that women's contributions to the field are encouraged and celebrated. Uncovering and relating lost stories about the pivotal contributions of women in vertebrate paleontology doesn't just make for enthralling storytelling, but also helps ensure a richer and more diverse future for this vibrant field. Illuminating the discoveries, collections, and studies of fossil vertebrates conducted by women in vertebrate paleontology, Rebels, Scholars, Explorers will be on every paleontologist's most-wanted list and should find a broader audience in the burgeoning sector of readers from all backgrounds eager to learn about women in the sciences.

BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY Finalist for the Los Angeles Times Book Prize "A powerful mix of science and ethics . . . This book is required reading for every concerned citizen--the material it covers should be discussed in schools, colleges, and universities throughout the country."-- New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR--a revolutionary new technology that she helped create--to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences, to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create "better" humans. Writing with fellow researcher Sam Sternberg, Doudna--who has since won the Nobel Prize for her CRISPR research--shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. "The future is in our hands as never before, and this book explains the stakes like no other." -- George Lucas "An invaluable account . . . We owe Doudna several times over." -- Guardian

One of the Financial Times' Best Summer Books of 2022 'A compelling account of the trials, tribulations and triumphs of life as a vet - and a lesson to us all on how we should treat the animals with which we share our lives.' - Stephen Moss, naturalist and author Dr Sean Wensley is an award-winning vet and lifelong naturalist who has contributed to animal welfare and conservation projects all over the world. His debut book is about how we can choose a better life for animals, from the chickens we eat to the pets we keep. As our societies become more urbanised, we are further removed from the reality of where and how our food is produced. Surveys suggest that nearly 1 in 4 UK adults don't know that bacon comes from pigs. On the opposite end of the spectrum, the humanisation of our pets is a risk to their welfare; with over 60% of UK dogs being overweight or obese, we are effectively killing them with kindness. Through A Vet's Eyes seeks to redress this imbalance so that we see all animals as thinking, feeling beings not dissimilar to ourselves. As he takes us through the years in which he trained to become a vet, and set against a backdrop of inspiring natural spectacles, Dr Wensley shares his first-hand experience of how animals are treated and used for our benefit. He interrogates the different levels of welfare afforded to them and reveals how we the general consumer can reduce our animal welfare footprint through the choices we make every day.

'A fascinating and beautifully written memoir that reminds us what we have with our NHS - and what we stand to lose' Christie Watson 'A tour de force... lyrical and riveting prose' Abraham Verghese, author of Cutting for Stone How do medical staff offer care and hope to patients and families when faced with the mayhem and lottery of a broken healthcare system? The People's Hospital is the story of how Ben Taub Hospital strives to provide healthcare to Houston's most vulnerable population, against the background of the chaos of American healthcare . By telling the frequently heartbreaking stories of patients who have had to battle their desperate financial circumstances as well as life-threatening disease - from Rogelio, a twenty-something ,undocumented immigrant from Mexico recently diagnosed with fatal kidney disease, to Roxana, a Salvadoran woman who appears in ER after a life-saving surgery resulted in her developing gangrene , and many more. These are extraordinary stories in which doctors are tied up with complex moral questions about money vs healthcare, and patients manipulate their health conditions in dangerous ways in order to be eligible for lifesaving treatment that they cannot afford.

J. B. S. Haldane's life was rich and strange, never short on genius or drama-from his boyhood apprenticeship to his scientist father, who first instilled in him a devotion to the scientific method; to his time in the trenches during the First World War, where he wrote his first scientific paper; to his numerous experiments on himself, including inhaling dangerous levels of carbon dioxide and drinking hydrochloric acid; to his clandestine research for the British Admiralty during the Second World War. He is best remembered as a geneticist who revolutionized our understanding of evolution, but his peers hailed him as a polymath. One student called him "the last man who might know all there was to be known." He foresaw in vitro fertilization, peak oil, and the hydrogen fuel cell, and his contributions ranged over physiology, genetics, evolutionary biology, mathematics, and biostatistics. He was also a staunch Communist, which led him to Spain during the Civil War and sparked suspicions that he was spying for the Soviets. He wrote copiously on science and politics in newspapers and magazines, and he gave speeches in town halls and on the radio-all of which made him, in his day, as famous in Britain as Einstein. It is the duty of scientists to think politically, Haldane believed, and he sought not simply to tell his readers what to think but to show them how to think. Beautifully written and richly detailed, Samanth Subramanian's A Dominant Character recounts Haldane's boisterous life and examines the questions he raised about the intersections of genetics and politics-questions that resonate even more urgently today.

This book outlines the scientific career of Arto Salomaa, a pioneer in theoretical computer science and mathematics. The author first interviewed the subject and his family and collaborators, and he then researched this fascinating biography of an intellectual who was key in the development of these fields. Early chapters progress chronologically from Academician Salomaa's origins, childhood, and education to his professional successes in science, teaching, and publishing. His most impactful direct research efforts have been in the areas of automata and formal languages. Beyond that he has influenced many more scientists and professionals through collaborations, teaching, and books on topics such as biocomputing and cryptography. The author offers insights into Finnish history, culture, and academia, while historians of computer science will appreciate the vignettes describing some of the people who have shaped the field from the 1950s to today. The author and his subject return throughout to underlying themes such as the importance of family and the value of longstanding collegial relationships, while the work and achievements are leavened with humor and references to interests such as music, sport, and the sauna.

Fresh out of training, Dr. Chuck Radis moves with his wife and daughter to Peaks Island, Maine, to fulfill a Public Health scholarship obligation. Absent-minded and initially oblivious to island mores, Dr. Radis slowly adapts to a medical practice where x-rays and advanced laboratory testing are available only on the mainland. When he travels to the outer islands of Casco Bay for house calls, he relies on his physical examination skills and a tackle box of emergency medications to successfully manage his patients. With stories ranging from hilarious to heart breaking, Go by Boat is a respite from contemporary living, immersing the reader in the distinct culture of Maine island communities. Come along with Dr. Radis as he finds acceptance and friendship on the hardscrabble islands of Casco Bay.

This biography of the famous Soviet physicist Leonid Isaakovich Mandelstam (1889-1944), who became a Professor at Moscow State University in 1925 and an Academician (the highest scientific title in the USSR) in 1929, describes his contributions to both physics and technology. It also discusses the scientific community that formed around him, commonly known as the Mandelstam School. By doing so, it places Mandelstam's life story in its cultural context: the context of German University (until 1914), the First World War, the Civil War, and the development of the Socialist Revolution (until 1925) and the young socialist country. The book considers various general issues, such as the impact of German scientific culture on Russian science; the problems and fates of Russian intellectuals during the revolutionary and post-revolutionary years; the formation of the Soviet Academy of Science, the State Academy; and the transformation of the system of higher education in the USSR during the 1920s and 1930s. Further, it reconstructs Mandelstam's philosophy of science and his approach to the social and ethical function of science and science education based on his fundamental writings and lecture notes. This reconstruction is enhanced by extensive use of previously unpublished archive material as well as the transcripts of personal interviews conducted by the author. The book also discusses the biographies of Mandelstam's friends and collaborators: German mathematician and philosopher Richard von Mises, Soviet Communist Party official and philosopher B.M.Hessen, Russian specialist in radio engineering N.D.Papalexy, the specialists in non-linear dynamics A.A.Andronov, S.E. Chaikin, A.A.Vitt and the plasma physicist M.A.Leontovich. This second, extended edition reconstructs the social and economic backgrounds of Mandelstam and his colleagues, describing their positions at the universities and the institutes belonging to the Academy of Science. Additionally, Mandelstam's philosophy of science is investigated in connection with the ideological attacks that occurred after Mandelstam's death, particularly the great mathematician A.D.Alexandrov's criticism of Mandelstam's operationalism.

'Delightfully insightful and intensely readable [...] There is an energy and drama to Rory's writing which nonetheless leaves space for us, the reader, to make up our minds' - Stephen Fry We live at a time when billions have access to unbelievably powerful technology. The most extraordinary tool that has been invented in the last century, the smartphone, is forcing radical changes in the way we live and work - and unlike previous technologies it is in the hands of just about everyone. Coupled with the rise of social media, this has ushered in a new era of deeply personal technology, where individuals now have the ability to work, create and communicate on their own terms, rather than wait for permission from giant corporations or governments. At least that is the optimistic view. This book takes readers on an entertaining ride through this turbulent era, as related by an author with a ringside seat to the key moments of the technology revolution. We remember the excitement and wonder that came with the arrival of Apple's iPhone with all the promise it offered. We see tech empires rise and fall as these devices send shockwaves through every industry and leave the corporate titans of the analogue era floundering in their wake. We see that early utopianism about the potential of the mobile social revolution to transform society for the better fade, as criminals, bullies and predators poison the well of social media. And we hear from those at the forefront of the tech revolution, including Stephen Hawking, Elon Musk, Tim Berners-Lee, Martha Lane-Fox and Jimmy Wales, to gain their unique insights and predictions for what may be to come. Always On immerses the reader in the most important story of our times - the dramatic impact of hyperconnectivity, the smartphone and social media on everything from our democracy to our employment and our health. The final section of the book draws on the author's own personal experience with technology and medicine, considering how COVID-19 made us look again to computing in our battle to confront the greatest challenge of modern times.

All in Good Time is the remarkable story of George Daniels (1926-2011), the master craftsman, who was born into poverty but raised himself to become the greatest watchmaker of the twentieth century. Daniels stands alone in modern times as the inventor of the revolutionary co-axial escapement, the first substantial advance in portable mechanical timekeeping over the lever escapement, which has dominated ever since its invention in 1759. Daniels's love of mechanics embraced not only the minute, however - he was also a passionate collector and driver of historic motorcars. This revised and expanded edition of his autobiography also contains a new section that illustrates and discusses over thirty of the pocket and wrist-watches Daniels himself made over the years. Witness here the triumph of intelligence, ingenuity, matchless skill and singularity of purpose over the most unpromising of beginnings.

At 19, Isambard Kingdom Brunel was in charge, under his father, of an engineering work that is the wonder of Europe: the Thames tunnel, completed in 1843. This book traces Brunel's life and career, the man of immense energy who came to dominate civil engineering in the 19th century and whose legacy can still be seen nearly two centuries later. L T C Rolt was one of the first narrative historians, an industrial pioneer and preservationist. During his life he was fundamental in establishing and promoting canals, waterways and railways. He was one of the first people in modern Britain to draw attention to the value of our canals as a means of transport and a source of pleasure. As well as his interest in canals he also turned his attention to neglcted railways and set up the first organisation to save and run a railway with a mainly volunteer workforce.

Biologist James Watson and physicist Francis Crick's 1953 revelation about the double helix structure of DNA is the foundation of virtually every advance in our modern understanding of genetics and molecular biology. But how did Watson and Crick do it-and why were they the ones who succeeded? In truth, the discovery of DNA's structure is the story of a race among five scientists for advancement, fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins and Linus Pauling. They were fascinating and brilliant, with strong personalities that often clashed. But it is Rosalind Franklin who becomes a focal point for Howard Markel. The Secret of Life is a story of genius and perseverance but also a saga of cronyism, misogyny, anti-Semitism and misconduct. Markel brilliantly recounts the intense intellectual journey-and the fraught personal relationships-that resulted in the discovery of DNA.

An acclaimed biography of the Enlightenment's greatest mathematician This is the first full-scale biography of Leonhard Euler (1707-1783), one of the greatest mathematicians and theoretical physicists of all time. In this comprehensive and authoritative account, Ronald Calinger connects the story of Euler's eventful life to the astonishing achievements that place him in the company of Archimedes, Newton, and Gauss. Drawing on Euler's massive published works and correspondence, this biography sets Euler's work in its multilayered context-personal, intellectual, institutional, political, cultural, religious, and social. It is a story of nearly incessant accomplishment, from Euler's fundamental contributions to almost every area of pure and applied mathematics in his time-especially calculus, mechanics, and optics-to his advances in shipbuilding, telescopes, acoustics, ballistics, cartography, chronology, and music theory.

'This terrific memoir... is utterly gripping' Mail on Sunday 'Read this book and be inspired to reach for the impossible' Brian Greene Many children dream of becoming an astronaut when they grow up, but when a six-year-old Mike Massimino saw Neil Armstrong walk on the moon he knew what he wanted to do when he became an adult. But NASA rejected him; then when he applied again they turned him down because of his poor eyesight. For the next year he trained his eyes to work better and finally, at the third time of asking, NASA accepted him. So began Massimino's 18-year career as an astronaut, and the extraordinary lengths he went to to get accepted was only the beginning. In this awe-inspiring memoir, he reveals the hard work, camaraderie and sheer guts involved in the life of an astronaut; he vividly describes what it is like to strap yourself into the Space Shuttle and blast off into space, or the sensation of walking in space, as he did when he completed a mission to service the Hubble telescope. He also talks movingly about the Columbia tragedy, and how it felt to step into the Space Shuttle again in the aftermath of that disaster. Massimino was inspired by the film The Right Stuff, and this book is not only a tribute to those fellow astronauts he worked with, but also a stunning example of someone who had exactly those attributes himself.

When the world stopped, all hopes rested on finding a vaccine. One team answered the call and were ready to act. But how do you develop a life-saving drug when every second counts and one mistake could be catastrophic?

Married couple and decades-long research partners Ugur Sahin and Özlem Türeci did just that within weeks of the pandemic breaking out. From convincing Big Pharma to support their ambitious project, to navigating political interference from the Trump administration and the European Union, the road to producing the Pfizer/BioNTech vaccine was by no means smooth. But these cutting-edge innovators overcame every obstacle to provide more than two billion doses of the life-saving drug to countries all around the world in record time.

The Vaccine draws back the curtain on one of the most important medical breakthroughs of our age, containing contributions from the fascinating couple themselves, as well as more than 50 scientists, politicians, public health officials, and BioNTech staff.

Shedding a light on the science behind the breakthrough, The Vaccine tells the story of the trailblazers to whom we all owe a debt of gratitude. More suspenseful than a novel, this is a real-life story of an extraordinary race against time to save the world.

Explorers and travellers have always been attracted by the lure of the unknown. By traversing and mapping our planet, they have played a vital role in mankind's development. For almost two hundred years, the Royal Geographical Society has recognised their achievements by awarding its prestigious gold medals to those who have contributed most to our knowledge of the world. Taking us on a journey across mountains and deserts, oceans and seas, Exploring the World tells the stories of more than eighty of these extraordinary men and women. Some, such as David Livingstone, Scott of the Antarctic and Jacques-Yves Cousteau, are well known; whilst others, such as William Chandless and Ney Elias, are today less familiar. Some dreamed of being the first to sight a lake or a river; others sighted some of the world's greatest natural features by chance. Some were naturalists, anthropologists or mountaineers; others went in search of explorers who had vanished without trace, or had been shipwrecked or marooned. Filled with epic tales of endurance and perseverance, Exploring the World celebrates a group of exceptional individuals possessed of indomitable courage, boundless determination and adventurous spirit. It portrays a variety of fascinating lives driven by curiosity, wanderlust and the pursuit of knowledge - and, in doing so, provides a unique overview of two centuries of exploration.

Nnedi Okorafor was never supposed to be paralyzed. A college track star and budding entomologist, Nnedi's lifelong battle with scoliosis was just a bump in her plan - something a simple surgery would easily correct. But when Nnedi wakes from the surgery to find she can't move her legs, her entire sense of who she is begins to waver. Confined to a hospital bed for months, unusual things begin to happen. Psychedelic bugs crawl her hospital walls; strange dreams visit her nightly. She begins to feel as if she's turning into a cyborg. Unsure if she'll ever walk again, Nnedi begins to put these experiences into writing, conjuring up strange, fantastical stories. What Nnedi discovers during her confinement would prove to be the key to her life as a successful science fiction writer: In science fiction, when something breaks, something greater often emerges from the cracks. While she may be bedridden, instead of stopping her journey Nnedi's paralysis opens up new windows in her mind, kindles her creativity and ultimately leads her to become more alive than she ever could have imagined. Nnedi takes the reader on a journey from her hospital bed deep into her memories, from her painful first experiences with racism as a child in Chicago to her powerful visits to her parents' hometown in Nigeria, where she got her first inkling that science fiction has roots beyond the West. This was not the Africa that Nnedi knew from Western literature - an Africa that she always read was a place left behind. The role of technology in Nigeria opened her eyes to future-looking Africa: cable TV and cell phones in the village, 419 scammers occupying the cybercafes, the small generator connected to her cousin's desktop computer, everyone quickly adapting to portable tech devices due to unreliable power sources. Nnedi could see that Africa was far from broken, as she'd been taught, and her experience there planted the early seeds of sci-fi - a genre that speculates about technologies, societies, and social issues - from an entirely new lens. In Broken Places & Outer Spaces, Nnedi uses her own experience as a jumping off point to follow the phenomenon of creativity born from hardship. From Frida Kahlo to Mary Shelly, she examines great artists and writers who have pushed through their limitations, using hardship to fuel their work. Through these compelling stories and her own, Nnedi reveals a universal truth: What we perceive as limitations have the potential to become our greatest strengths - far greater than when we were unbroken.

We think of the Stephensons and Brunel as the fathers of the railways, and their Liverpool and Manchester and Great Western Railways as the prototypes of the modern systems. But who were the railways' grandfathers and great-grandfathers? The rapid evolution of the railways after 1830 depended on the juggernauts of steam locomotion being able to draw upon centuries of experience in using and developing railways, and of harnessing the power of steam. Giants the Stephensons and others may have been, but they stood upon the foundations built by many other considerable - if lesser-known - talents. This is the story of those early pioneers of steam.