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Books > Science & Mathematics > Biology, life sciences > Botany & plant sciences > Plant physiology
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Biology of Inositols and Phosphoinositides (Paperback, Softcover reprint of hardcover 1st ed. 2006)
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Biology of Inositols and Phosphoinositides (Paperback, Softcover reprint of hardcover 1st ed. 2006)
Series: Subcellular Biochemistry, 39
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From being to becoming important, myo-inositol and its derivatives
including phosphoinositides and phosphoinositols involved in
diversi?ed functions in wide varieties of cells overcoming its
insigni?cant role had to wait more than a century. Myo-inositol,
infact, is the oldest known inositol and it was isolated from
muscle as early as 1850 and phytin (Inositol hexakis phosphate)
from plants by Pfeffer in 1872. Since then, interest in inositols
and their derivatives varied as the methodology of isolation and
puri?cation of the stereoisomers of inositol and their derivatives
advanced. Phosphoinositides were ?rst isolated from brain in 1949
by Folch and their structure was established in 1961 by Ballou and
his coworkers. After the compilation of scattered publications on
cyclitols by Posternak (1965), proceedings of the conference on
cyclitols and phosphoinositides under the supervision of
Hoffmann-Ostenhof, were p- lished in 1969. Similar proceedings of
the second conference on the same s- ject edited by Wells and
Eisenberg Jr was published in 1978. In that meeting at the
concluding session Hawthorne remarked "persued deeply enough p-
haps even myoinositol could be mirror to the whole universe." This
is now infact the scenario on the research on inositol and their
phosphoderivatives. Finally a comprehensive information covering
the aspects of chemistry, b- chemistry and physiology of inositols
and their phosphoderivatives in a book entitled Inositol Phosphates
written by Cosgrove (1980) was available.
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