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Enzymes of the Cholinesterase Family (Paperback, Softcover reprint of the original 1st ed. 1995)
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Discovery Miles 66 470
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Enzymes of the Cholinesterase Family (Paperback, Softcover reprint of the original 1st ed. 1995)
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The Fifth International Meeting on Cholinesterases convened in
Madras, India, in September of 1994. The long and rich history and
culture of India provided an excellent setting for the meeting.
More than 120 delegates from Asia, Australia, Europe and North
America heard 54 oral presentations and viewed 54 posters on
current research on enzymes of the cholinesterase family. The aim
of this book is to compile the presentations of the Fifth
International Meeting on Cholinesterases into a volume that
describes recent investigations on the structure and catalytic
function of acetylcholinesterase (AChE), butyrylcholinesterase
(BuChE) and related enzymes, as well as studies on the molecular
and cellular biology of these enzymes and the genes which encode
them. Cholinesterases enjoy a long and storied history in diverse
areas. In basic biochemical research, AChE is one of the best
studied, though yet enigmatic, of enzymes. The efficient catalytic
function of this enzyme presents the biochemist with a fundamental
challenge in understanding the relationship between structure and
function. AChE and BuChE belong to a family of proteins, the alB
hydrolase fold family, whose constituents evolutionarily diverged
from a common ancestor. Proteins in this family have a wide range
of physiological functions. In commerce, AChE is a prime target for
agricultural insect control, and for the development of therapeutic
agents for Alzheimer's disease.
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