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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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DNA-Protein Interactions (Paperback, Softcover reprint of the original 1st ed. 1993)
Loot Price: R2,819
Discovery Miles 28 190
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DNA-Protein Interactions (Paperback, Softcover reprint of the original 1st ed. 1993)
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Our understanding of the mechanisms regulating gene expression,
which determine the patterns of growth and development in all
living organisms, ultimately involves the elucidation of the
detailed and dy namic interactions of proteins with nucleic acids
-both DNA and RNA. Until recently the commonly presented view of
the DNA double helix as visualized on the covers of many textbooks
and journals - was as a monotonous static straight rod incapable in
its own right of directing the processes necessary for the
conservation and selective reading of genetic information. This
view, although perhaps extreme, was reinforced by the necessary
linearity of genetic maps. The reality is that the biological
functions of both DNA and RNA are dependent on complex, and
sometimes transient, three-dimensional nucleoprotein structures in
which genetically distant elements are brought into close spatial
proximity. It is in such structures that the enzymatic manipulation
of DNA in the essential biological processes as DNA replication,
transcription and recombination are effected - the complexes are
the mediators of the 'DNA transactions' of Hatch Echols."
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