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Books > Medicine > Other branches of medicine > Pharmacology > Medical toxicology
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Silver in Healthcare - Its Antimicrobial Efficacy and Safety in Use (Hardcover, Edition.)
Loot Price: R4,163
Discovery Miles 41 630
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Silver in Healthcare - Its Antimicrobial Efficacy and Safety in Use (Hardcover, Edition.)
Series: Issues in Toxicology, Volume 6
Expected to ship within 10 - 15 working days
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Silver in healthcare has many different facets and since the early
concepts of microbiology of the 1880's, has been developed from
usage in surgical clips, staples, foil wound dressings and surgical
implants, to the widespread and clinically effective antiseptic
wound dressings, sutures, catheters, bone and dental implants, and
cardiovascular devices of today. From the dawn of human
civilisation, silver has had a role of water purification and even
now has a role in hospital water systems for control of MRSA and
legionnaires disease. Biotechnological advances in recent years
have extended the antimicrobial properties of silver into
production of hygiene textiles and use in domestic products.
Important advances have been made in understanding mechanisms of
antimicrobial action of silver, the central importance of
ionisation patterns in the presence of body fluids and secretion,
and the genetical and molecular profiles of silver resistance. This
publication is a comprehensive account of the history of silver in
medicine, its clinical benefits and wide advantages as a broad
spectrum antimicrobial agent. It is clear from the extensive array
of publications in recognised and unofficial press, that many
misconceptions and misleading conceptions have been perpetuated,
leading to errors in evaluation of the safety of the metal in
occupational, domestic and therapeutic situations. The book is
unique in that it is the only comprehensive presentation of the
toxicology of silver and it identifies the major misconceptions in
the safety of silver and interpretation of argyria and argyrosis as
central features of silver toxicity. In this book, Dr Lansdown
reviews the literature from a clinical and experimental viewpoint,
with the benefit of his many years research on silver and
experience gained in working with clinicians, healthcare product
manufacturers and microbiologists. There is also discussion in the
book on the relevance of antimicrobial resistance to silver and
deficiencies in present day clinical practice in not evaluating
incidences of resistance on a routine basis. The subject matter is
presented in a readable fashion and includes reference to use of
the metal in such practices as acupuncture and treatment of
tropical diseases as practised in some parts of the world, each of
which is accompanied by special clinical risk. It is also a
collation of current views on the use and efficacy of silver as a
broad spectrum antibiotic. The chapters which deal specifically
with toxicological aspects of silver in clinical, occupational and
environmental issues are central to the book's value. The book is
aimed at clinicians, research scientists and product manufacturers
and will provide ideas for new research and academic endeavour. It
is also essential reading for research students with an interest in
metal toxicity and its management in mammalian tissues.
General
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