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Books > Medicine > Clinical & internal medicine > Geriatric medicine
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Early Life Origins of Ageing and Longevity (Hardcover, 1st ed. 2019)
Loot Price: R4,332
Discovery Miles 43 320
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Early Life Origins of Ageing and Longevity (Hardcover, 1st ed. 2019)
Series: Healthy Ageing and Longevity, 9
Expected to ship within 12 - 17 working days
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This book provides a comprehensive overview of the field of
developmental programming of ageing phenotypes. Although
gerontological research has traditionally focused on later stages
of the life cycle, growing evidence indicates that both the rate of
ageing-associated functional declines, and the risks of later-life
chronic pathological conditions, can be traced to origins early in
life. While other books in the field concentrate on the
developmental origin of particular disorders, this volume offers a
detailed guide to all important aspects of the role of early-life
conditions in programming both chronic pathological conditions and
the ageing process. Interest in the study of ageing and longevity
had its beginnings in research on the fetal origins of adult
disease. This has evolved into a hypothesis on the Developmental
Origins of Adult Health and Disease (DOHaD), which postulates that
adverse environmental exposures during critical in-utero and early
postnatal stages of development may permanently change
physiological responses and cause functional impairments and
disorders in adult life. In this book, the contributing authors and
leading experts from around the world, describe research on
mechanisms underlying the developmental programming phenomenon, as
well as interventional strategies aimed at restoring
developmentally disrupted epigenetic patterns. Early Life Origins
of Ageing and Longevity benefits a wide audience of working
scientists, clinicians, and advanced students, and will also
interest scientifically curious general readers who wish to know
more about current research in this rapidly evolving field.
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