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Books > Medicine > Clinical & internal medicine > Paediatric medicine
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Rett Disorder and the Developing Brain (Paperback)
Loot Price: R2,398
Discovery Miles 23 980
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Rett Disorder and the Developing Brain (Paperback)
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Rett disorder, first described by Andreas Rett in 1966, is a
condition which involves the functions on which intelligence and
expression depend. It is probably the most common genetic disorder
encountered in profoundly intellectually disabled females. Its many
manifestations include epilepsy, scoliosis, nutritional
difficulties, and disorders of mood and movement. This book
provides an up-to-date account of current research into the
disorder at a time when the causative mutations have just been
discovered on the MeCP2 gene. The first section of the book
presents the clinical signs and the latest research into the
genetic, neuro- anatomical and neuro-chemical aspects of Rett
disorder. The second section moves on to deal with the
neuro-physiological research, concentrating on the autonomic
system, which is deeply implicated in the disease mechanisms. The
final section of the book examines the behavioural and
psychological features of Rett disorder and discusses issues
relating to communication. The chapters are written by a
distinguished, international team of experts, all currently active
in research. The contributions bring our understanding of the Rett
disorder right up-to-date, as the study of the condition moves from
an era of description into a time when there are real possibilities
for beneficial interventions.
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