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The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish (Hardcover, 1st ed. 2017)
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The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish (Hardcover, 1st ed. 2017)
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Animal models and tests have become increasingly important for
biomedical research, enabling a better understanding of pathogenic
pathways involved in various human disorders. Over the last
decades, zebrafish (Danio rerio) have become a very popular model
organism in biomedical research. Recently, this fish has entered
the waters of neuroscience and biological psychiatry, quickly
becoming an indispensable model species in this field. With a high
genetic homology to humans (~75% based on coding regions), it is
not surprising that humans and fish are very similar
physiologically (and behaviorally). Therefore, it should not come
as a surprise that zebrafish can be an excellent model of human
neuropsychiatric disorders. While some classical psychiatrists may
not too easily be persuaded by this generalization, the current
book "The rights and wrongs of zebrafish: principles of behavioral
phenotyping and CNS disease modeling" explains, in a
domain-by-domain manner, how exactly zebrafish models can be used
to target a wide range of human brain disorders and aberrant
phenotypes. The contributors to this book are leading international
scholars whose work spearheads innovative zebrafish neuroscience
research around the world. Written by top experts in the field,
this book makes for a useful, balanced and up-to-date reading that
outlines the use of zebrafish to study the pathological mechanisms
underlying neuropsychiatric disorders.
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