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Books > Medicine > Surgery > Plastic & reconstructive surgery
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Microsurgical Models in Rats for Transplantation Research (Paperback, Softcover reprint of the original 1st ed. 1985)
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Discovery Miles 42 930
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Microsurgical Models in Rats for Transplantation Research (Paperback, Softcover reprint of the original 1st ed. 1985)
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Preclinical experimental transplantation research that is based on
microsurgical models in rats fulfills two indispensable conditions
for modern organ transplanta tion research: Almost all organ grafts
can be performed on the rat with an amount of technical effort that
is still justifiable. Thus transplantation models that are
analogous to human organ transplantation can be developed, tested,
and evaluated. This fulfills a necessary condition from the
standpoint of surgery. With the species rat, we have a great
variety of genetically different inbred strains. From the
immunological point of view this is an indispensable prerequisite
for the investigation of preclinical transplantation models that
can be expected to produce controllable, reproducible results. In
vivo experimental results can be supplemented by and correlated to
in vitro tests. Lately these experimental results are being greatly
expanded and more precisely defined by the application of
immunohistological methods that have been established recently in
Kiel. In this book we hope to present a cross section of the
microsurgical models in use today and of current immunological and
immunohistological models. Furthermore, we wish to record the
present state of microsurgical organ transplantation research and
to show its relationship to the current state and development of
clinical organ transplantation. A special aspect of our Kiel
research group is the long-term, well-functioning,
interdisciplinary cooperation between surgery, immunology, and
pathology. Through this cooperation we attempt to provide an
atmosphere in which theoretical and practical viewpoints can
mutually influence each other."
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