Non-Myeloablative Allogeneic Transplantation (Paperback, Softcover reprint of the original 1st ed. 2002)

Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic therapy to prepare patients for allografting of hematopoietic stem cells and lymphocytes. It has the potential to deliver the potent anti-tumor immunotherapy and bone marrow replacement capacity of allogeneic stem cell transplantation to patients with reduced treatment-related morbidity and mortality. It may also enable allogeneic transplantation in patients who would be considered ineligible for conventional transplants because of co-morbidity or advanced age. However, this approach may necessitate more careful monitoring of post-transplant chimerism and malignant disease-status than is usual with conventional allografting. There is also controversy regarding the best preparative regimen and graft-versus-host disease prophylaxis to use.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Cancer Treatment and Research, 110
Release date:	March 2013
First published:	2002
Editors:	Asad Bashey • Edward D. Ball
Dimensions:	235 x 155 x 12mm (L x W x T)
Format:	Paperback
Pages:	216
Edition:	Softcover reprint of the original 1st ed. 2002
ISBN-13:	978-1-4613-5304-1
Categories:	Books > Medicine > Surgery > Transplant surgery Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-4613-5304-1
Barcode:	9781461353041

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