Congenital and acquired bone defects constitute a central problem
of traumatology and orthopedics. In order to cure these defects it
is often necessary to fill up the bones operatively with suitable
substances. Recently, so-called bone substitutes (collagen,
gelatine, bone matrix, calcium phospate, hydroxyapatite) have also
been recommended. Following an introductory presentation of bone
regeneration and transplants, these substitutes are discussed here
in a comprehensive survey of the literature. Particular attention
is given to the significance of mineral substance such as
hydroxyapatite, which will undoubtedly find a place in bone surgery
owing to its outstanding bioactivity and biotolerance. The implants
examined are also of significance for maxillofacial surgery and
dentistry. The histologic techniques in the staining of
undecalcified bone preparations and in histomorphometry are
presented in a special chapter.
General
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