In the past few decades there has been incredible growth in
"bionano"-related research, which has been accompanied by numerous
publications in this field. Although various compilations address
topics related to deoxyribonucleic acid (DNA) and protein, there
are few books that focus on determining the structure of
ribonucleic acid (RNA) and using RNA as building blocks to
construct nanoarchitectures for biomedical and healthcare
applications.
RNA Nanotechnology is a comprehensive volume that details both
the traditional approaches and the latest developments in the field
of RNA-related technology. This book targets a wide audience: a
broad introduction provides a solid academic background for
students, researchers, and scientists who are unfamiliar with the
subject, while the in-depth descriptions and discussions are useful
for advanced professionals.
The book opens with reviews on the basic aspects of RNA biology,
computational approaches for predicting RNA structures, and
traditional and emerging experimental approaches for probing RNA
structures. This section is followed by explorations of the latest
research and discoveries in RNA nanotechnology, including the
design and construction of RNA-based nanostructures. The final
segment of the book includes descriptions and discussions of the
potential biological and therapeutic applications of small RNA
molecules, such as small/short interfering RNAs (siRNAs), microRNAs
(miRNAs), RNA aptamers, and ribozymes.
General
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