Investigations into Calabar beans (the dried ripe seeds of
Physostigma venenosum) and their alkaloidal components compose a
classical scientific journey throughout some one-and-a-half
centuries and not only represent a fascinating aspect of the
history of medicine but which is, moreover, still ongoing at the
forefront of chemical and medical discovery. Those in particular
involving its major such component, l-physostigmine, have led to an
understanding of some of the fundamental mechanisms occurring in
physiology, pharmacology and biochemistry and, either actually or
potentially (by providing a template and thereby acting as a
“lead compound”) have provided a useful treatment for a variety
of neurological disorders associated with irregularities in
cholinergic transmission in which augmentation of cholinergic
activity has proved to be beneficial.
General
Imprint: |
Springer
|
Country of origin: |
Netherlands |
Release date: |
March 2023 |
Firstpublished: |
2023 |
Authors: |
Brian Robinson
|
Dimensions: |
235 x 155mm (L x W) |
Format: |
Hardcover
|
Pages: |
267 |
Edition: |
1st ed. 2023 |
ISBN-13: |
978-9402411904 |
Categories: |
Books
|
LSN: |
9402411909 |
Barcode: |
9789402411904 |
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