Cost-effective strategies for designing novel drug delivery
systems that target a broad range of disease conditions
"In vivo "imaging has become an important tool for the
development of new drug delivery systems, shedding new light on the
pharmacokinetics, biodistribution, bioavailability, local
concentration, and clearance of drug substances for the treatment
of human disease, most notably cancer. Written by a team of
international experts, this book examines the use of quantitative
imaging techniques in designing and evaluating novel drug delivery
systems and applications.
"Drug Delivery Applications of Noninvasive Imaging" offers a
full arsenal of tested and proven methods, practices and guidance,
enabling readers to overcome the many challenges in creating
successful new drug delivery systems. The book begins with an
introduction to molecular imaging. Next, it covers: "In vivo"
imaging techniques and quantitative analysisImaging drugs and drug
carriers at the site of action, including low-molecular weight
radiopharmaceuticals, peptides and proteins, siRNA, cells, and
nanoparticlesApplications of imaging techniques in administration
routes other than intravenous injection, such as pulmonary and oral
deliveryTranslational research leading to clinical
applicationsImaging drug delivery in large animal modelsClinical
applications of imaging techniques to guide drug development and
drug delivery
Chapters are based on a thorough review of the current
literature as well as the authors' firsthand experience working
with imaging techniques for the development of novel drug delivery
systems.
Presenting state-of-the-technology applications of imaging in
preclinical and clinical evaluation of drug delivery systems, "Drug
Delivery Applications of Noninvasive Imaging "offers cost-effective
strategies to pharmaceutical researchers and students for
developing drug delivery systems that accurately target a broad
range of disease conditions.
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