This book is the only published literature that comprehensively
discusses all aspects of transfusion of transmissible diseases, the
facts and the fiction. It is of paramount importance to all
involved in the vein to vein chain of transfusion medicine.
Session I addresses the basic blood safety aspects including the
need for quality management, rational donor screening and the risks
of blood transfusion for prenatal developmental toxicity.
Session II addresses the gamma of transmissible infectious
agents from bacteria through parasites and tick-borne agents to
prions and the risks associated with xeno-transplantation and
xenozoonoses
Session III sheds new light on NAT technology for detection of
viral DNA and RNA, the cost-effectiveness of the alternatives to
allogeneic blood transfusion. To what extent are genetic defects in
stem cell genomic structures transmissible through transplantation
and does questioning potential donors make any sense?
Session IV addresses the preventive aspects on the future of
transfusion medicine. Quantitative real-time PCR for Parvo B19 and
advances in bacterial detection technology. The advancement from
theory to practice of pathogen inactivation technology based on
destruction of nucleic acids in cellular structures. Finally, a
plea is made for co-operation and collaboration on a global scale,
changing the pars pro toto phenomenon (the ships that pass in the
night) for a totum pro parte, a true joining of forces to create a
global network for blood safety and structured blood supply
systems.
Transmissible Diseases and Blood Transfusion is an important
reference for all hematologists and researchers involved in
transfusion medicine.
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