Mitochondrial Function and Biogenesis (Paperback, Softcover reprint of hardcover 1st ed. 2004)

Mitochondria are complex organelles, possessing a double-membrane and even their own genome, the mtDNA. They play a pivotal role in cellular metabolism, respiration, and production of ATP essential for the normal function of all human organ systems. It is not surprising, therefore, that genetic defects of mitochondrial functions cause a wide spectrum of human diseases. This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level. The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome evolution and mtDNA stability, mitochondrial biogenesis and protein quality control, mitochondrial morphology, assembly and function of the mitochondrial energy generation apparatus and mitochondrial metabolic pathways. These are particularly oriented to link in these various mitochondrial pathways to the clinical consequences of their dysfunctions.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Topics in Current Genetics, 8
Release date:	December 2010
First published:	2004
Editors:	Carla Koehler • Matthias F. Bauer
Dimensions:	235 x 155mm (L x W)
Format:	Paperback
Pages:	333
Edition:	Softcover reprint of hardcover 1st ed. 2004
ISBN-13:	978-3-642-05994-0
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Promotions
LSN:	3-642-05994-5
Barcode:	9783642059940

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