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Introduction to Macromolecular Binding Equilibria (Hardcover) Loot Price: R5,425
Discovery Miles 54 250
Introduction to Macromolecular Binding Equilibria (Hardcover): Charles P. Woodbury

Introduction to Macromolecular Binding Equilibria (Hardcover)

Charles P. Woodbury

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Loot Price R5,425 Discovery Miles 54 250 | Repayment Terms: R508 pm x 12*

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Macromolecules in the body form noncovalent associations, such as DNA-protein or protein-protein complexes, that control and regulate numerous cellular functions. Understanding how changes in the concentration and conformation of these macromolecules can trigger physiological responses is essential for researchers developing drug therapies to treat diseases affected by these imbalances.

Introduction to Macromolecular Binding Equilibria gives students in medicinal chemistry, pharmaceuticals, and bioengineering the necessary background in biophysical chemistry for research applications in drug discovery and development. Building upon a fundamental knowledge of calculus and physical chemistry, this compact, graduate-level text prepares students for advanced work in solution thermodynamics and binding phenomena and applying methods in this book to their own research.

This book describes the underlying theory of binding phenomena and explains how to apply the binding polynomial approach for building models and interpreting data. It also covers practical considerations for setting up binding experiments and describes how to obtain true thermodynamic isotherms unbiased by model assumption via model-free analysis of binding data.

General

Imprint: Crc Press
Country of origin: United States
Release date: November 2007
First published: 2007
Authors: Charles P. Woodbury
Dimensions: 234 x 156 x 20mm (L x W x T)
Format: Hardcover
Pages: 272
ISBN-13: 978-1-4200-5298-5
Categories: Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics
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LSN: 1-4200-5298-5
Barcode: 9781420052985

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