Sulfurtransferases: Essential Enzymes for Life stands as the first comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, each chapter covers a specific sulfurtransferase, including its basic biology and roles in healthy functioning, disease, drug discovery, and other biotechnological applications. The physiological function for each enzyme is considered in depth, along with regulation mechanisms, pharmacological inhibitors, and pathology and conditions related to altered enzymatic activity. Sulfurtransferases discussed include rhodanese, MST, thiosulfate-thiol sulfurtransferase, tRNA uracil 4-sulfurtransferase, thiosulfate-dithiol sulfurtransferases, biotin synthase, cysteine desulfurase, lipoyl synthase, molybdenum cofactor sulfurtransferase, thiazole synthase, molybdopterin synthase sulfurtransferase, molybdopterin synthase, tRNA-uridine 2-sulfurtransferase, tRNA-5-taurinomethyluridine 2-sulfurtransferase, tRNA-5-methyluridine (54) 2-sulfurtransferase, and L-aspartate semialdehyde sulfurtransferase, among others. Here, researchers will discover key knowledge and recent advances to bring forward new studies on this increasingly relevant class of enzymes, while clinicians may apply new findings in medical practice.

Data Assimilation for the Geosciences: From Theory to Application, Second Edition brings together all of the mathematical and statistical background knowledge needed to formulate data assimilation systems into one place. It includes practical exercises enabling readers to apply theory in both a theoretical formulation as well as teach them how to code the theory with toy problems to verify their understanding. It also demonstrates how data assimilation systems are implemented in larger scale fluid dynamical problems related to land surface, the atmosphere, ocean and other geophysical situations. The second edition of Data Assimilation for the Geosciences has been revised with up to date research that is going on in data assimilation, as well as how to apply the techniques. The new edition features an introduction of how machine learning and artificial intelligence are interfacing and aiding data assimilation. In addition to appealing to students and researchers across the geosciences, this now also appeals to new students and scientists in the field of data assimilation as it will now have even more information on the techniques, research, and applications, consolidated into one source.

Human Biochemistry, Second Edition provides a comprehensive, pragmatic introduction to biochemistry as it relates to human development and disease. Here, Gerald Litwack, award-wining researcher and longtime teacher, discusses the biochemical aspects of organ systems and tissue, cells, proteins, enzymes, insulins and sugars, lipids, nucleic acids, amino acids, polypeptides, steroids, and vitamins and nutrition, among other topics. Fully updated to address recent advances, the new edition features fresh discussions on hypothalamic releasing hormones, DNA editing with CRISPR, new functions of cellular prions, plant-based diet and nutrition, and much more. Grounded in problem-driven learning, this new edition features clinical case studies, applications, chapter summaries, and review-based questions that translate basic biochemistry into clinical practice, thus empowering active clinicians, students and researchers.

Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research, Second Edition presents a catalog of fundamental information on the structure and function of hormones from basic biology to clinical use, offering a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors, signaling pathways, and the biological activities they regulate. The book's stellar editorial board, affiliated with the Japan Society for Comparative Endocrinology, brings together authors that present a compelling structure of each hormone with a consistent presentation that provides a primer surrounding the plethora of hormones that now exist. Comparative endocrinology continues to rapidly expand and new information about hormones is being produced almost daily, making it important to stay up-to-date. Hormone, paracrine, and autocrine factors have been identified as key players in a range of different systems, including immune, musculoskeletal and cardiovascular. Frontiers between disciplines are being blurred and many scientists in fields other than endocrinology are interested in hormones. Scientists now have the unprecedented opportunity to look from invertebrates to vertebrate and identify novel regulatory factors and understand their function and how they determine an organism's physiology and survival.

High-Density Sequencing Applications in Microbial Molecular Genetics, Volume 612 in the Methods of Enzymology series provides the latest on the high-density sequencing of DNA and cDNA libraries and how they have revolutionized contemporary research in biology. Methods permitting tens of millions of sequence reads in a single experiment have paved the way to genome-wide studies that are contributing to our understanding of the complexity of living systems. Chapters in this updated volume include Characterizing the role of exoribonucleases in the control of microbial gene expression: Differential RNA seq., Conformational studies of bacterial chromosomes by high-throughput sequencing methods, Measuring mRNA degradation, and more. Addition sections cover Global recognition patterns of bacterial RNA-binding proteins, High-resolution profiling of NMD targets, and the Generation of a metagenomic 3C/Hi-C library of human gut microbiota, Genome-wide mapping of yeast retrotransposons integration target sites, Measuring protein synthesis rates, Finding unsuspected partners of small RNAs with new screening approaches, Use of multiplexed transcriptomics to define the relationship between promoter sequence and transcription output, RNA-based control of quorum sensing in Vibrio cholerae, amongst other highly regarded topics.

Progress in Molecular Biology and Translational Science, Volume 160 provides the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series gives in-depth knowledge on the important molecular biological aspects of organismal physiology and function, along with insights on how this knowledge can be applied to understand and ameliorate human disease. This updated release covers Clinical Drugs in the Environment, Group I Intron Trans-Splicing, Adult Stem Cells on Regenerative Therapy, CRISPR in Animals and Animal Models, The Role of 3'-5'Exoribonucleases in RNA Degradation, and more.

Everyday Applied Geophysics 2: Electromagnetics and Magnetics covers the physical methods permitting the environmental exploration of the sub-surface in 1, 2, 3 or 4 dimensions (the latter for time-lapse in terms of physical environmental state and geometry). The book specifically addresses the feasible methods that are accessible and affordable to all users, providing a simple apparatus of electronic diagrams and free, Internet open-source software links for data interpretation.

Advances in Geophysics is a highly-respected publication in the field of geophysics. Since 1952, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 50 volumes, the series contains much material still relevant today - truly an essential publication for researchers in all fields of geophysics.

This volume and its companion Volume 351 will supplement Volume 194 of MIE. The guides are specifically designed to meet the needs of graduate students and postdocs as well as researchers. Whether an established researcher or newcomer to the field, these volumes will contain all the up-to-date methods needed to study "Genes in Yeast." Procedures are included to enable newcomers to set up a yeast laboratory and to master basic manipulations. Relevant background and reference information will be given for proven procedures that can be used as a guide for developing protocols in a number of disciplines.

Chemical Thermodynamics: Principles and Applications presents a thorough development of the principles of thermodynamics--an old
science to which the authors include the most modern applications, along with those of importance in developing the science and those of
historical interest. The text is written in an informal but rigorous style, including ancedotes about some of the great thermodynamicists (with some of whom the authors have had a personal relationship), and focuses on "real" systems in the discussion and figures, in contrast to the generic examples that are often used in other textbooks.
The book provides a basic review of thermodynamic principles, equations, and applications of broad interest. It covers the development of thermodynamics as one of the pre-eminent examples of an exact science. A discussion of the standard state that emphasizes its significance and usefulness is also included, as well as a more rigorous and indepth treatment of thermodynamics and discussions of a wider variety of applications than are found in more broadly based physical chemistry undergraduate textbooks.
Combined with its companion book, Chemical Thermodynamics: Advanced Applications, the practicing scientist will have a complete reference set detailing chemical thermodynamics.
Key Features
* Outlines the development of the principles of thermodynamics, including the most modern applications along with those of importance in developing the science and those of historical interest
* Provides a basic review of thermodynamic principles, equations, and applications of broad interest
* Treats thermodynamics as one of the preeminent examples of an exact science
* Provides a more rigorous and indepth treatment of thermodynamics and discussion of a wider variety of applications than are found in more
broadly based physical chemistry undergraduate textbooks
* Includes examples in the text and exercises and problems at the end of each chapter to assist the student in learning the subject
* Provides a complete set of references to all sources of data and to supplementary reading sources

This book contains the proceedings of the 16th ICEC/ICMC Conference, held in Kitakyushu, Japan, on 20th-24th May 1996. The Proceedings are presented in three volumes containing a total of 476 papers from 1484 authors.

The proceedings covers the main areas of: Large Scale Refrigeration. Cryocoolers. Cryogenic Engineering. Space Cryogenics. Application of Superconductivity. Oxide Superconductors. Metallic Superconductors. Metallic Materials. Non Metallic Materials.

In addition there are seven Plenary Lectures covering such diverse topics as commercialization of high-Tc superconductors, the continuing development of the Maglev system in Japan, and the Large Hadron Collider project.

The Proceedings comprise an excellent and up-to-date summary of research and development in the fields of Cryogenics and Superconductivity.

Dalton's theory of the atom is generally considered to be what made the atom a scientifically fruitful concept in chemistry. To be sure, by Dalton's time the atom had already had a two-millenium history as a philosophical idea, and corpuscular thought had long been viable in natural philosophy (that is, in what we would today call physics).
Atoms in Chemistry will examine episodes in the evolution of the concept of the atom, particularly in chemistry, from Dalton's day to our own. It begins with an overview of scientific atomic theories from the 17th through 20th centuries that analyzes corpuscular theories of matter proposed or entertained by natural philosophers in the 17th century. Chapters will focus on philosophical and religious conceptions of matter, 19th-century organic structural theories, the debate surrounding the truth of the atomic-molecular theory, and physical evidence accumulated in the late 19th and early 20th centuries that suggested that atoms were actually real, even if they were not exactly as Dalton envisioned them. The final chapter of this book takes the reader beyond the atom itself to some of the places associated with the history of scientific atomism. As a whole, this volume will serve as a passport to important episodes from the more than 200-year history of atoms in chemistry.

The chapters in this monograph are contributions from the Advances in Quantum Monte Carlo symposium held at Pacifichem 2010, International Chemical Congress of Pacific Basin Societies. The symposium was dedicated to celebrate the career of James B. Anderson, a notable researcher in the field. Quantum Monte Carlo provides an ab initio solution to the Schroedinger equation by performing a random walk through configuration space in imaginary time. Benchmark calculations suggest that its most commonly-used variant, "fixed-node" diffusion Monte Carlo, estimates energies with an accuracy comparable to that of high-level coupled-cluster calculations. These two methods, each having advantages and disadvantages, are complementary "gold-standards" of quantum chemistry. There are challenges facing researchers in the field, several of which are addressed in the chapters in this monograph. These include improving the accuracy and precision of quantum Monte Carlo calculations; understanding the exchange nodes and utilizing the simulated electron distribution; extending the method to large and/or experimentally-challenging systems; and developing hybrid molecular mechanics/dynamics and Monte Carlo algorithms.

The emphasis of Planetary Atmospheres is on comparative aspects of planetary atmospheres, generally meaning comparison with the Earth, including atmospheric composition, thermal structure, cloud properties, dynamics, weather and climate, and aeronomy. The goal is to look for common processes at work under different boundary conditions in order to reach a fundamental understanding of the physics of atmospheres. As part of a general Physics course, the material is chosen to emphasise certain aspects that will be of broad topical interest:
- evolutionary processes, setting the Earth in its context as a planet and a member of the Solar System
- the properties of atmospheres that affect the climate near the surface of each planet
- measurement techniques and models, where the same experimental and theoretical physics is applied under different conditions to investigate and explain atmospheric behaviour.
These might be thought of as the astronomical, environmental, and technical sides of the discipline respectively.
The book covers the basic physics of planetary atmospheres in a single text for students or anyone interested in this area of science. The approach is the same as in the author's previous book Elementary Climate Physics: an overview, followed by more detailed discussion of key topics arranged by physical phenomenon and not planet by planet as usually found in this field. There is an emphasis on acquiring and interpreting measurements, and the basic physics of instruments and models, with key definitions and some historical background in footnotes and in the glossary at the end of the book.

From a star astrophysicist, a journey into the world of particle physics and the cosmos -- and a call for more just, inclusive practice of science.

Science, like most fields, is set up for men to succeed, and is rife with racism, sexism, and shortsightedness as a result. But as Dr. Chanda Prescod-Weinstein makes brilliantly clear, we all have a right to know the night sky. One of the leading physicists of her generation, she is also one of the fewer than one hundred Black women to earn a PhD in physics. You will enjoy -- and share -- her love for physics, from the Standard Model of Particle Physics and what lies beyond it, to the physics of melanin in skin, to the latest theories of dark matter -- all with a new spin and rhythm informed by pop culture, hip hop, politics, and Star Trek.

This vision of the cosmos is vibrant, inclusive and buoyantly non-traditional. By welcoming the insights of those who have been left out for too long, we expand our understanding of the universe and our place in it.

The Disordered Cosmos is a vision for a world without prejudice that allows everyone to view the wonders of the universe through the same starry eyes.

Flight dynamics create important research problems in the process of helicopter design. They involve advanced design ideas and engineering technology theories. This book concerns flight theory and research methods for helicopter flight science and technology. The contents include the fundamentals of rotor aerodynamics, helicopter trim, helicopter stability and control, and helicopter performance analyses. The book also lokks at the kinematics, dynamics, control, and aerodynamics of the helicopter during maneuvering flight. With an emphasis on the physical concepts, the characteristics of rotor flapping, theoretical analyses and numerical simulation methods for helicopter flight mechanics are detail described in detail. The book is primarily intended for senior undergraduates and postgraduates who major in aerospace engineering. It is also a good reference book for helicopter engineers interested design and operational engineering. It lays a foundation for the study of helicopter aeromechanics.

Energy, water, affordable healthcare and global warming are four major concerns resulting from resource depletion, record high oil prices, clean water shortages, high costs of pharmaceuticals, and changing climate conditions. Among many potential solutions, advance in membrane technology is one of the most direct, effective and feasible approaches to solve these sophisticated issues. This membrane book presents cutting-edge membrane research and development for water reuse and desalination, energy development including biofuels, CO2 capture, pharmaceutical purification and separation, and biomedical applications.

Advances in Quantum Monte Carlo confronts the challenges in quantum mechanics that have become progressively more prevalent in the last five years. This book will cover the needed advances in Quantum Monte Carlo methods including improvements and a complete range of applications. Advances in Quantum Monte Carlo will also include a complete spectrum of applications.

The pioneer astronauts who took America into space tell their personal stories about the challenges they faced -- their fears, joys, friendships, and successes.

Chosen from hundreds of crackerjack pilots for their fitness, intelligence, and courage, the original Mercury Seven astronauts risked their lives to cross the space frontier. In "We Seven, " they take readers behind the scenes to show them their training, technology, and teamwork, and to share personal stories, including the lighter moments of their mission. They bring readers inside the Mercury program -- even into the space capsules themselves. "We Seven" straps you in with the astronauts and rockets you along for the ride.

Share Alan Shepard's exhilaration as he breaks through the earth's atmosphere. Endure moments of panic with Gus Grissom when his hatch blows, stranding him in the open sea. Race with John Glenn as he makes split-second life-or-death maneuvers during reentry, and feel his relief when he emerges safe but drenched with sweat.

Despite such heroism, Project Mercury was more than the story of individual missions. It defined the manned space flight program to come, from Gemini through Apollo. In "We Seven, " America's original astronauts tell us firsthand -- as only they can -- about the space program they pioneered, and share with us the hopes and dreams of the U.S. at the dawn of a new era.

Advances in Microbial Physiology, Volume 83 in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Topics of interest in this update include RidA paradigm, Targeting the cell envelope to overcome antimicrobial resistance, Biosynthesis and function of microbial methylmenaquinones, Antibiotic efficacy, Role of central metabolism/bacterial physiology on tolerance to cell wall-acting antibiotics, and Physiology of diazotrophs.