Bringing his cosmic perspective to civilization on Earth, Neil deGrasse Tyson, bestselling author of Astrophysics for People in a Hurry, shines new light on the crucial fault lines of our time–war, politics, religion, truth, beauty, gender, race, and tribalism–in a way that stimulates a deeper sense of unity for us all. In a time when our political and cultural perspectives feel more divisive than ever, Tyson provides a much-needed antidote to so much of what divides us, while making a passionate case for the twin engines of enlightenment–a cosmic perspective and the rationality of science. After thinking deeply about how a scientist views the world and about what Earth looks like from space, Tyson has found that terrestrial thoughts change as our brain resets and recalibrates life's priorities, along with the actions we might take in response. As a result, no outlook on culture, society, or civilisation remains untouched. In Starry Messenger, Tyson reveals just how human the enterprise of science is. Far from a cold, unfeeling undertaking, scientific methods, tools, and discoveries have shaped modern civilisation and created the landscape we've built for ourselves on which to live, work, and play. Tyson shows how an infusion of science and rational thinking renders worldviews deeper and more informed than ever before–and exposes unfounded perspectives and unjustified emotions. With crystalline prose and an abundance of evidence, Starry Messenger walks us through the scientific palette that sees and paints the world differently. From lessons on resolving global conflict to reminders of how precious it is to be alive, Tyson reveals, with warmth and eloquence, ten surprising, brilliant, and beautiful truths of human society, informed and enlightened by knowledge of our place in the universe.

'David Christian's approach to understanding history can help all of us learn to prepare for the future' - Bill Gates A user's guide to the future: from the algorithms in DNA to why time is like a cocktail glass, interstellar migrations, transhumanism, the fate of the galaxy, and the last black hole... Every second of our lives - whether we're looking both ways before crossing the street, celebrating the birth of a baby, or moving to a new city - we must cope with an unknowable future. How do we do this? And how do we, like most living organisms, manage this impossible challenge quite well (at least most of the time)? David Christian, historian and bestselling author of Origin Story, is renowned for pioneering the emerging discipline of Big History, which surveys the whole of the past. But with Future Stories, he casts his sharp analytical eye forward, offering an introduction to the strange world of the future, and a guide to what we think we know about it at all scales, from the predictive mechanisms of single-celled organisms and tomato plants to the merging of colossal galaxies billions of years from now. Drawing together science, history and philosophy from a huge range of places and times, Christian explores how we prepare for uncertain futures, including the future of human evolution, artificial intelligence, interstellar travel, and more. By linking the study of the past much more closely to the study of the future, we can begin to imagine what the world will look like in the next hundred years and consider solutions to the biggest challenges facing us all.

'Witty, approachable and captivating' - Robin Ince 'A fascinating exploration of how we learned what matter really is' - Sean Carroll 'A delightfully fresh and accessible approach to one of the great quests of science' - Graham Farmelo 'Lays out not just what we know, but how we found out (and what is left to be discovered' - Katie Mack 'If you wish to make an apple pie from scratch, you must first invent the universe' - Carl Sagan Inspired by Sagan's famous line, How To Make An Apple Pie From Scratch sets out on a journey to unearth everything we know about our universe: how it started, how we found out, and what we still have left to discover. Will we ever be able to understand the very first moments of the world we inhabit? What is matter really made of? How did anything survive the fearsome heat of the Big Bang? In pursuit of answers, we meet the scientists, astronomers and philosophers who brought us to our present understanding of the world - offering readers a front-row seat to the most dramatic journey human beings have ever embarked on. Harry Cliff's How To Make An Apple Pie From Scratch is an essential, fresh and funny guide to how we got to where we are now - and what we have to come.

The pioneer astronauts who took America into space tell their personal stories about the challenges they faced -- their fears, joys, friendships, and successes.

Chosen from hundreds of crackerjack pilots for their fitness, intelligence, and courage, the original Mercury Seven astronauts risked their lives to cross the space frontier. In "We Seven, " they take readers behind the scenes to show them their training, technology, and teamwork, and to share personal stories, including the lighter moments of their mission. They bring readers inside the Mercury program -- even into the space capsules themselves. "We Seven" straps you in with the astronauts and rockets you along for the ride.

Share Alan Shepard's exhilaration as he breaks through the earth's atmosphere. Endure moments of panic with Gus Grissom when his hatch blows, stranding him in the open sea. Race with John Glenn as he makes split-second life-or-death maneuvers during reentry, and feel his relief when he emerges safe but drenched with sweat.

Despite such heroism, Project Mercury was more than the story of individual missions. It defined the manned space flight program to come, from Gemini through Apollo. In "We Seven, " America's original astronauts tell us firsthand -- as only they can -- about the space program they pioneered, and share with us the hopes and dreams of the U.S. at the dawn of a new era.

'David Christian's approach to understanding history can help all of us learn to prepare for the future' - Bill Gates A user's guide to the future: from the algorithms in DNA to why time is like a cocktail glass, interstellar migrations, transhumanism, the fate of the galaxy, and the last black hole... Every second of our lives - whether we're looking both ways before crossing the street, celebrating the birth of a baby, or moving to a new city - we must cope with an unknowable future by telling stories about what will happen next. Where is the future, the place where we set those stories? Can we trust our future stories? And what sort of futures do they show us? David Christian, historian and bestselling author of Origin Story, is renowned for pioneering the emerging discipline of Big History, which surveys the whole of the past. But with Future Stories, he casts his sharp analytical eye forward, offering an introduction to the strange world of the future, and a guide to what we think we know about it at all scales, from the predictive mechanisms of single-celled organisms and tomato plants to the merging of colossal galaxies billions of years from now. Drawing together science, history and philosophy from a huge range of places and times, Christian explores how we prepare for uncertain futures, including the future of human evolution, artificial intelligence, interstellar travel, and more. By linking the study of the past much more closely to the study of the future, we can begin to imagine what the world will look like in the next hundred years and consider solutions to the biggest challenges facing us all.

Authored by world-class scientists and scholars, the Handbook of Natural Resources, Second Edition, is an excellent reference for understanding the consequences of changing natural resources to the degradation of ecological integrity and the sustainability of life. Based on the content of the bestselling and CHOICE awarded Encyclopedia of Natural Resources, this new edition demonstrates the major challenges that the society is facing for the sustainability of all wellbeing on planet Earth. The experience, evidence, methods, and models used in studying natural resources are presented in six stand-alone volumes, arranged along the main systems: land, water, and air. It reviews state-of-the-art knowledge, highlights advances made in different areas, and provides guidance for the appropriate use of remote sensing data in the study of natural resources on a global scale. The six volumes in this set cover: Terrestrial Ecosystems and Biodiversity; Landscape and Land Capacity; Wetlands and Habitats; Fresh Water and Watersheds; Coastal and Marine Environments; and finally Atmosphere and Climate. Written in an easy-to-reference manner, the Handbook of Natural Resources, Second Edition, as a complete set, is essential for anyone looking for a deeper understanding of the science and management of natural resources. Public and private libraries, educational and research institutions, scientists, scholars, and resource managers will benefit enormously from this set. Individual volumes and chapters can also be used in a wide variety of both graduate and undergraduate courses in environmental science and natural science courses at different levels and disciplines, such as biology, geography, Earth system science, ecology, etc.

New York Times bestseller Journey into the universe through the most spectacular sights in astronomy in stereoscopic 3D Welcome to the Universe in 3D takes you on a grand tour of the observable universe, guiding you through the most spectacular sights in the cosmos-in breathtaking 3D. Presenting a rich array of stereoscopic color images, which can be viewed in 3D using a special stereo viewer that folds easily out of the cover of the book, this book reveals your cosmic environment as you have never seen it before. Astronomy is the story of how humankind's perception of the two-dimensional dome of the sky evolved into a far deeper comprehension of an expanding three-dimensional cosmos. This book invites you to take part in this story by exploring the universe in depth, as revealed by cutting-edge astronomical research and observations. You will journey from the Moon through the solar system, out to exoplanets, distant nebulas, and galaxy clusters, until you finally reach the cosmic microwave background radiation (or CMB), the most distant light we can observe. The distances to these celestial wonders range from 1.3 light-seconds to 13.8 billion light-years. Along the way, the authors explain the fascinating features of what you are seeing, including how the 3D images were made using the same technique that early astronomers devised to measure distances to objects in space. The dramatic 3D images in this one-of-a-kind book will astonish you, extending your vision out to the farthest reaches of the universe. You will never look up into the night sky the same way again.

Monitoring drought’s slow evolution and identifying the end of a drought is still a big challenge for scientists, natural resource managers, and decision makers. This comprehensive two-volume set with contributions from over 200 experts, and featuring case studies representing numerous countries throughout the world, discusses different aspects of drought from types, indices, and forecasting to monitoring, modeling, and mitigation measures. It also addresses how climate change is impacting drought and decision-making concluding with lessons learned about science, policy, and managing uncertainty. Features: Provides a global perspective on drought prediction and management and a synthesis of the recent state of knowledge. Covers a wide range of topics from essential concepts and advanced techniques for forecasting and modeling drought to societal impacts, consequences, and planning Presents numerous case studies with different management approaches from different regions and countries. Addresses how climate change impacts drought, the increasing challenges associated with managing drought, decision making, and policy implications. Includes contributions from hundreds of experts around the world. Professionals, researchers, academics, and postgraduate students with knowledge in Environmental Sciences, Ecology, Agriculture, Forestry, Hydrology, Water Resources Engineering, and Earth Sciences, as well as those interested in how climate change impacts drought management, will gain new insights from the experts featured in this two-volume handbook.

'A wonderful book about Stephen Hawking's biggest legacy' Spectator 'This superbly written book offers insight into an extraordinary individual, the creative process, and the scope and limits of our current understanding of the cosmos' Sir Martin Rees Stephen Hawking's closest collaborator offers the intellectual superstar's final thoughts on the cosmos. Perhaps the biggest question Stephen Hawking tried to answer in his extraordinary life was how the universe could have created conditions so perfectly hospitable to life. In order to solve this mystery, Hawking studied the big bang origin of the universe, but his early work ran into a crisis when the math predicted many big bangs producing a multiverse - countless different universes, most of which would be far too bizarre to ?harbour life. Holed up in the theoretical physics department at Cambridge, Stephen Hawking and his friend and collaborator Thomas Hertog worked on this problem for twenty years, developing a new theory of the cosmos that could account for the emergence of life. Peering into the extreme quantum physics of cosmic holograms and venturing far back in time, they were startled to find a deeper level of evolution in which the physical laws themselves transform and simplify until particles, forces, and even time itself fades away. This discovery led them to a revolutionary idea: The laws of physics are not set in stone but are born and co-evolve as the universe they govern takes shape. As Hawking's final days drew near, the two collaborators published their theory, which proposed a radical new Darwinian perspective on the origins of our universe. On the Origin of Time offers a striking new vision of the universe's birth that will profoundly transform the way we think about our place in the order of the cosmos and may ultimately prove to be Hawking's greatest legacy.

Every rock has a story tell, and none more so than those which have fallen from the sky: meteorites. Originating in the Asteroid Belt between Mars and Jupiter, these rocky fragments offer clues not just to the earliest origins of the Solar System but also to Earth's very survival into the future. Sky at Night presenter, Dr Tim Gregory takes us on a journey through the very earliest days of our Solar System to the spectacular meteorite falls that produced 'fiery rain' in 1792, to the pre-solar grains (literally stardust) that were blown in from other solar systems and are the oldest solid objects ever discovered on earth. Meteorites reveal a story much bigger than ourselves or our planet. As Tim says, 'it is an epic beyond compare'.

Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties. The benefits of medical image synthesis have sparked growing interest in a number of advanced clinical applications, such as magnetic resonance imaging (MRI)-only radiation therapy treatment planning and positron emission tomography (PET)/MRI scanning. This book will be a comprehensive and exciting resource for undergraduates, graduates, researchers, and practitioners.

The Textbook of Ion Channels is a set of three volumes providing a wide-ranging reference source on ion channels for students, instructors, and researchers. Ion channels are membrane proteins that control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli like light, sound, odor, and taste, and regulate the response to physical stimuli like temperature and pressure. In non-excitable tissues, ion channels are instrumental for the regulation of basic salt balance that is critical for homeostasis. Ion channels are located at the surface membrane of cells, giving them the unique ability to communicate with the environment, as well as the membrane of intracellular organelles, allowing them to regulate internal homeostasis. Ion channels are fundamentally important for human health and diseases, and are important targets for pharmaceuticals in mental illness, heart disease, anesthesia, pain and other clinical applications. The modern methods used in their study are powerful and diverse, ranging from single ion-channel measurement techniques to models of ion channel diseases in animals, and human clinical trials for ion channel drugs. All three volumes give the reader an introduction to fundamental concepts needed to understand the mechanism of ion channels, a guide to the technical aspects of ion channel research, offer a modern guide to the properties of major ion channel families, and include coverage of key examples of regulatory, physiological, and disease roles for ion channels.

This textbook provides an accessible introduction to physics for undergraduate students in the life sciences, including those majoring in all branches of biology, biochemistry, and psychology and students working on pre-professional programs such as pre-medical, pre-dental, and physical therapy. The text is geared for the algebra-based physics course, often named College Physics in the United States. The order of topics studied are such that most of the problems in the text can be solved with the methods of Statics or Dynamics. That is, they require a free body diagram, the application of Newton’s Laws, and any necessary kinematics. Constructing the text with a standardized problem-solving methodology, simplifies this aspect of the course and allows students to focus on the application of physics to the study of biological systems. Along the way, students apply these techniques to find the tension in a tendon, the sedimentation rate of red blood cells in haemoglobin, the torques and forces on a bacterium employing a flagellum to propel itself through a viscous fluid, and the terminal velocity of a protein moving in a Gel Electrophoresis device. This is part one of a two-volume set; volume 2 introduces students to the conserved-quantities and applies these problem-solving techniques to topics in Thermodynamics, Electrical Circuits, Optics, and Atomic and Nuclear Physics always with continued focus on biological applications.

From a star astrophysicist, a journey into the world of particle physics and the cosmos -- and a call for more just, inclusive practice of science.

Science, like most fields, is set up for men to succeed, and is rife with racism, sexism, and shortsightedness as a result. But as Dr. Chanda Prescod-Weinstein makes brilliantly clear, we all have a right to know the night sky. One of the leading physicists of her generation, she is also one of the fewer than one hundred Black women to earn a PhD in physics. You will enjoy -- and share -- her love for physics, from the Standard Model of Particle Physics and what lies beyond it, to the physics of melanin in skin, to the latest theories of dark matter -- all with a new spin and rhythm informed by pop culture, hip hop, politics, and Star Trek.

This vision of the cosmos is vibrant, inclusive and buoyantly non-traditional. By welcoming the insights of those who have been left out for too long, we expand our understanding of the universe and our place in it.

The Disordered Cosmos is a vision for a world without prejudice that allows everyone to view the wonders of the universe through the same starry eyes.

Good and effective treatment in radiotherapy requires careful consideration of the complex variables involved as well as critical assessment of the techniques. This new edition of an established classic takes into account advances in imaging and treatment delivery and reflects the current state of the art in the practice of radiotherapy, emphasizing the underlying principles of treatment that can be applied for conventional, conformal, and novel treatments.

All of the Earth's ocean, from the equator to the poles, is a single engine powered by sunlight - a blue machine. Human history has been dictated by the ocean: the location of cities, access to resources and the gateways to new lands have all revolved around water. We live inside the weather the ocean generates and breathe in what it breathes out. Yet despite our dependence, our awareness of its totality is minimal. In a book that will recalibrate our view of this defining feature of our planet, physicist Helen Czerski dives deep to illuminate the murky depths of the ocean engine, examining the messengers, passengers and voyagers that live in it, travel over it, and survive because of it. From the ancient Polynesians who navigated the Pacific by reading the waves to permanent residents of the deep such as the Greenland shark that can live for hundreds of years, she explains the vast currents, invisible ocean walls and underwater waterfalls that all have their place in the ocean's complex, interlinked system. Timely, elegant and passionately argued, The Blue Machine is one of the biggest stories ever told. The understanding it offers is crucial to our future. Drawing on years of experience at the forefront of marine science, Helen Czerski captures the magnitude and subtlety of this complex force, showing us the thrilling extent to which we are at the mercy of this great engine.

Right now, you are orbiting a black hole. The Earth orbits the Sun, and the Sun orbits the centre of the Milky Way: a supermassive black hole, the strangest and most misunderstood phenomenon in the galaxy. In A Brief History of Black Holes, the award-winning University of Oxford researcher Dr Becky Smethurst charts five hundred years of scientific breakthroughs in astronomy and astrophysics. She takes us from the earliest observations of the universe and the collapse of massive stars, to the iconic first photographs of a black hole and her own published findings. A cosmic tale of discovery, Becky explains why black holes aren't really 'black', that you never ever want to be 'spaghettified', how black holes are more like sofa cushions than hoovers and why, beyond the event horizon, the future is a direction in space rather than in time. Told with humour and wisdom, this captivating book describes the secrets behind the most profound questions about our universe, all hidden inside black holes. 'A jaunt through space history . . . with charming wit and many pop-culture references' - BBC Sky At Night Magazine

Changes and additions to the new edition of this classic textbook include a new chapter on symmetries, new problems and examples, improved explanations, more numerical problems to be worked on a computer, new applications to solid state physics, and consolidated treatment of time-dependent potentials.

A new theory of the universe, twenty years in the making, by Stephen Hawking and his close collaborator Thomas Hertog. Perhaps the biggest question Stephen Hawking tried to answer in his extraordinary life was how the universe could have created conditions so perfectly hospitable to life. Pondering this mystery led Hawking to study the big bang origin of the universe, but his early work ran into a crisis when the maths predicted many big bangs producing a multiverse - countless different universes, most of which were far too bizarre to harbour life. Holed up in the theoretical physics department at Cambridge, Stephen Hawking and his friend and collaborator Thomas Hertog worked shoulder to shoulder for twenty years on a new quantum theory of the cosmos. As their discoveries took them deeper into the big bang, they were startled to find a deeper level of evolution in which the physical laws themselves transform and simplify until particles, forces, and even time itself fades away. Once upon a time, perhaps, there was no time. This led them to a revolutionary idea: the laws of physics are not set in stone but are born and co-evolve as the universe they govern takes shape. On the Origin of Time takes the reader on a quest to understand questions bigger than our universe, peering into the extreme quantum physics of black holes and the big bang and drawing on the latest developments in string theory. As Hawking's final days drew near, the two collaborators published a final theory proposing their radical new Darwinian perspective on the origins of our universe. Hertog offers a striking new vision that ties together, more deeply than ever, the nature of the universe's birth with our existence. Their theory profoundly transforms the way we think about our place in the order of the cosmos and may ultimately prove Hawking's biggest legacy.

Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties. The benefits of medical image synthesis have sparked growing interest in a number of advanced clinical applications, such as magnetic resonance imaging (MRI)-only radiation therapy treatment planning and positron emission tomography (PET)/MRI scanning. This book will be a comprehensive and exciting resource for undergraduates, graduates, researchers, and practitioners.