The monograph introduces the reader to the world of inductive well logging - an established method for surveying the electrical conductivity of rocks surrounding a borehole. The emphasis is on developing a theory of inductive logging and on understanding logging tools basic physics, since this theory and understanding furnish valuable insights for inventing practical induction logging techniques.

The first chapter of the book presents the basic laws of electromagnetism from a point of view that will facilitate the application of the theory to problems in electromagnetic logging. Many topics that play an important role in the design and interpretation of tools readings are covered. The vertical resolution and radial depth of investigation of different induction tools is systematically considered. Special attention is paid to principles of induction logging with transversal induction coils, to transient method of induction logging in media with cylindrical and horizontal interfaces and to the influence of anisotropy on the electromagnetic field measured in a conducting medium. Multi-coil differential induction probes and induction logging based on measuring the inphase component of the secondary field or the quadrature component difference are also described in detail. The last chapter is devoted to mathematical modeling of the response of induction logging tools in 3D geometries. The theory of inductive logging presented in this volume can be applied to logging after drilling as well as logging while drilling.

These proceedings present selected research papers from CSNC2017, held during 23th-25th May in Shanghai, China. The theme of CSNC2017 is Positioning, Connecting All. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC2017, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.

This book presents contributions from the joint event 8th INGEO International Conference on Engineering Surveying and 4th SIG Symposium on Engineering Geodesy, which was planned to be held in Dubrovnik, Croatia, on April 1-4, 2020 and was canceled due to COVID-19 pandemic situation. Editors, in cooperation with the Local Organisers, are decided to organize the Conference on-line at October 22-23, 2020. We would like to invite you to participation through http://ingeo-sig2020.hgd1952.hr/index.php/2020/08/31/ingeosig2020-virtual-conference-october-22-23-2020/. The event brought together professionals in the fields of civil engineering and engineering surveying to discuss new technologies, their applicability, and operability.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.

This book describes the physical and chemical effects of radiation interaction with matter. Beginning with the physical basis for the absorption of charged particle radiations, Fundamentals of Radiation Chemistry provides a systematic account of the formation of products, including the nature and properties of intermediate species. Developed from first principles, the coverage of fundamentals and applications will appeal to an interdisciplinary audience of radiation physicists and radiation biologists. Only an undergraduate background in chemistry and physics is assumed as a prerequisite for the understanding of applications in research and industry.
Key Features
* Provides a working knowledge of radiation effects for students and non-experts
* Stresses the role of the electron both as a radiation and as a reactant species
* Contains clear diagrams of track models
* Includes a chapter on applications
* Written by an expert with more than thirty years of experience in a premiere research laboratory
* Culled from the author's painstaking research of journals and other publications over several decades

How to Understand Quantum Mechanics presents an accessible introduction to understanding quantum mechanics in a natural and intuitive way, which was advocated by Erwin Schroedinger and Albert Einstein. A theoretical physicist reveals dozens of easy tricks that avoid long calculations, makes complicated things simple, and bypasses the worthless anguish of famous scientists who died in angst. The author's approach is light-hearted, and the book is written to be read without equations, however all relevant equations still appear with explanations as to what they mean. The book entertainingly rejects quantum disinformation, the MKS unit system (obsolete), pompous non-explanations, pompous people, the hoax of the 'uncertainty principle' (it is just a math relation), and the accumulated junk-DNA that got into the quantum operating system by misreporting it. The order of presentation is new and also unique by warning about traps to be avoided, while separating topics such as quantum probability to let the Schroedinger equation be appreciated in the simplest way on its own terms. This is also the first book on quantum theory that is not based on arbitrary and confusing axioms or foundation principles. The author is so unprincipled he shows where obsolete principles duplicated basic math facts, became redundant, and sometimes were just pawns in academic turf wars. The book has many original topics not found elsewhere, and completely researched references to original historical sources and anecdotes concerting the unrecognized scientists who actually did discover things, did not all get Nobel prizes, and yet had interesting productive lives.

This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

In June of 1996, at the seaside resort of Guaruja, Brazil, a renowned group of researchers in space and astrophysical plasmas met to provide a forum on advanced topics on astrophysical and space plasmas at a school consisting of some 60 students and teachers, mainly from Brazil and Argentina, but also from all the other parts of the globe. The purpose was to provide an update on the latest theories, observations, and simulations of space-astrophysical plasma phenomena. The topics covered included: space plasma mechanisms for particle acceleration, nonthermal emission in cosmic plasma, magnetohydrodynamic instabilities in solar, interstellar, and other cosmic objects, magnetic field line reconnection and merging, the nonlinear and often chaotic structure of astrophysical plasmas, and the advances in high performance supercomputing resources to replicate the observed phenomena. The lectures were presented by Professor Mark Birkinshaw of the Harvard-Smithsonian Center for Astrophysics and the University of Bristol; Dr Anthony Peratt, Los Alamos National Laboratory Scientific Advisor to the United States Department of Energy; Dr Dieter Biskamp of the Max Planck Institute for Plasma Physics, Garching, Germany; Professor Donald Melrose, Director, Centre for Theoretical Astrophysics, University of Sydney, Australia; Professor Abraham Chian of the National Institute for Space Research, Brazil; and Professor Nelson Fiedler-Ferrara of the University of Sao Paulo, Brazil. As summarized by Professor Reuven Opher, Institute of Astronomy and Geophysics, University of Sao Paulo, the advanced or interested student of space and astrophysical plasmas will find reference to nearly all modern aspects in the field of Plasma Astrophysics and Cosmology in the presented lectures.

These proceedings present selected research papers from CSNC2017, held during 23th-25th May in Shanghai, China. The theme of CSNC2017 is Positioning, Connecting All. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC2017, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.

This book explains the anatomy and physiology of cartilage tissue in an integrated way. The emphasis is on how cartilage tissue functions and maintains homeostasis in a challenging mechanical environment. Supported by hundreds of references, the book posts new hypotheses explaining how cartilage adapts and achieves homeostasis in vivo, and tests them against available data. This exploratory approach creates a sense of discovery that the reader can join, or perhaps test themselves through their own research. The main benefit will be obtained by research students and professors looking to understand the deeper concepts that will further their own research, or clinicians (including health professionals and surgeons) who want to gain a deeper physiological understanding of cartilage tissue, which can then serve as a basis for more rational clinical decision-making they need to make on a daily basis. To help bridge the gap between basic science and clinically relevant joint disease, applications and interpretations of key physiological concepts are discussed in the context of osteoarthritis at the end of most chapters.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.
Key Features
* Catalysts of Protein Folding: Protein Disulfide Isomerases, Cis-trans Peptidyl Prolyl Isomerases
* Accessory Proteins: Chaperonins, Cochaperonins, Pap Proteins, Sec Proteins
* Physical methods for investigation of interactions between chaperones and their substances
* Cotranslational protein folding, cell-free protein synthesis and associated methods

This book uses new data from the very low radio frequency telescope LOFAR to analyse the magnetic structure in the giant radio galaxy NGC6251. This analysis reveals that the magnetic field strength in the locality of this giant radio galaxy is an order of magnitude lower than in other comparable systems. Due to the observational limitations associated with capturing such huge astrophysical structures, giant radio galaxies are historically a poorly sampled population of objects; however, their preferential placement in the more rarefied regions of the cosmic web makes them a uniquely important probe of large-scale structures. In particular, the polarisation of the radio emissions from giant radio galaxies is one of the few tools available to us that can be used to measure magnetic fields in regions where the strength of those fields is a key differentiator for competing models of the origin of cosmic magnetism. Low frequency polarisation data are crucial for detailed analyses of magnetic structure, but they are also the most challenging type of observational data to work with. This book presents a beautifully coupled description of the technical and scientific analysis required to extract valuable information from such data and, as the new generation of low frequency radio telescopes reveals the larger population of giant radio galaxies, it offers a significant resource for future analyses.

Of Clocks and Time takes readers on a five-stop journey through the physics and technology (and occasional bits of applications and history) of timekeeping. On the way, conceptual vistas and qualitative images abound, but since mathematics is spoken everywhere the book visits equations, quantitative relations, and rigorous definitions are offered as well. The expedition begins with a discussion of the rhythms produced by the daily and annual motion of sun, moon, planets, and stars. Centuries worth of observation and thinking culminate in Newton's penetrating theoretical insights since his notion of space and time are still influential today. During the following two legs of the trip, tools are being examined that allow us to measure hours and minutes and then, with ever growing precision, the tiniest fractions of a second. When the pace of travel approaches the ultimate speed limit, the speed of light, time and space exhibit strange and counter-intuitive traits. On this fourth stage of the journey, Einstein is the local tour guide whose special and general theories of relativity explain the behavior of clocks under these circumstances. Finally, the last part of the voyage reverses direction, moving ever deeper into the past to explore how we can tell the age of "things" - including that of the universe itself.

This book talks about photoplethysmography (PPG) techniques based on computer-aided data processing. In particular, it presents the results of a co-operative Indo-German project on the topic between Indian Institute of Technology at Chennai and RWTH Aachen University. Measuring system design, experimental details and some preliminary results obtained so far within the framework of this project are presented here. From the investigations carried out so far using the PPG sensors in conjunction with breathing sensors, it has been possible to monitor the 0.125 to 0.15 Hz rhythms in the arterial volumetric changes and to study the influence of breathing on them. These rhythms, which according to medical experts have relevance to psychosomatic conditions e.g. stress or relaxation, can also be addressed to by ancient Indian practices like yoga and meditation. This book presents the results of studying the effects of Indian relaxation techniques like pranayama, meditation, etc. in comparison to western relaxation techniques like autogenic training. So far it has been established that the Indian techniques of relaxation like yoga and meditation are very effective in generating low frequency rhythms in the skin perfusion as monitored by optical sensors. According to medical experts, these low frequency rhythms have a very important bearing on the human physiology and have potential therapeutic implications. This book is meant to provide an overview of the current state-of-knowledge and encourage the next generation of scientists/engineers to carry this work forward, especially on the novel PPG application fields that are of growing importance like pain and stress assessment, detection of peripheral venous saturation and local arterio-venous oxygen consumption as well as contactless space resolved skin perfusion studies with modern camera based PPG technology.

This monograph traces the development of our understanding of how and where energetic particles are accelerated in the heliosphere and how they may reach the Earth. Detailed data sets are presented which address these topics. The bulk of the observations are from spacecraft in or near the ecliptic plane. It is timely to present this subject now that Voyager-1 has entered the true interstellar medium. Since it seems unlikely that there will be a follow-on to the Voyager programme any time soon, the data we already have regarding the outer heliosphere are not going to be enhanced for at least 40 years.

This volume offers an overview of the state-of-the-art theoretical and practical approaches currently used for geophysical data interpretation. It includes new methods and techniques for solving data processing problems, and an analysis of geopotential fields by international researchers. It discusses topics such as: 1. Theoretical issues of interpretation of gravitational, magnetic and electric fields, including general methods of interpreting potential fields and other geophysical data. 2. Modern algorithms and computer technologies for interpretating geophysical fields. 3. The study of Earth deep structure using terrestrial and satellite potential field anomalies. 4. Geological interpretation of gravitational, magnetic and electric fields. This proceedings book is of interest to all geophysical researchers.

This book is intended to serve as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of nanotechnology in immunotherapy. The combination of nanotechnology and immunotherapy is recognized as a promising treatment modality. In particular, the use of nanoparticles in immunotherapy has attracted increased attention for their unique efficacy and specificity in cancer treatment. A wide variety of nanoparticles, such as polymeric and liposomal nanosystems, carbon nanotubes, and gold nanoparticles have provided important nanoplatforms for immunotherapeutic approaches. They have been shown to improve delivery and efficacy of immunotherapeutic agents such as vaccines or adjuvants. Nanoparticle-mediated thermal therapy has demonstrated the effectiveness for precise tumor cell ablation, radio-sensitization of hypoxic regions, enhancement of drug delivery, activation of thermosensitive agents, and enhancement of the immune system. Plasmonic nanoparticles are a special type of metallic nanoparticles that has received great interest due to their enhanced optical and electromagnetic properties and their superior capacity to convert photon energy into heat for selective photothermal therapy at the nanoscale level. Nanoparticle sizes can also be controlled such that they accumulate preferentially in tumors due to the enhanced permeability and retention effect of tumor vasculature. Various nanosystems such as gold nanoparticles have also been shown to stimulate the immune system. Immunotherapies could thus synergistically benefit from the combination with targeted nanoparticle-mediated photothermal therapies, especially when hyperthermia around immune-checkpoint inhibitors in the tumor bed is combined with precise thermal ablation of cancer cells. Of great importance is the possibility that such an approach can induce long-term immunological memory that can provide protection against tumor recurrence long after treatment of the initial tumors, like an 'anticancer vaccine'. Nanoparticle-mediated immunotherapy could lead to an entirely new treatment paradigm that challenges traditional surgical resection approaches for many cancers and metastases.

This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.

This accessible and entertaining biography chronicles the life and triumphs of astronomer Jan Hendrik Oort, who helped lay the foundations of modern astronomy in the 20th century. The book puts into context some of Oort's most significant achievements, including his discovery that the Milky Way rotates, as well as his famous hypothesis that our Solar System is surrounded by a reservoir of comets - now simply known as the Oort Cloud. Written by Oort's former student, this fascinating story also delves into Oort's pivotal role in the foundation of major astronomical facilities, including radio telescopes in the Netherlands and the European Southern Observatory (ESO), which now operates the most successful astronomical observatories in the world. The book draws extensively on new archival research through the Oort Archives, along with personal reminiscences by Oort's son and astronomer-grandson, to paint a more detailed picture of Oort's life not just as an astronomer, but also as a husband, father, and citizen. The strong public interest in comets triggered by the Rosetta mission to comet 67P/Churyumov-Gerasimenko and the recently discovered interstellar comet in the Solar System make this book particularly timely.

These proceedings present selected research papers from CSNC2017, held during 23th-25th May in Shanghai, China. The theme of CSNC2017 is Positioning, Connecting All. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC2017, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.

This thesis describes novel substrate embedded physical sensors that can be used to monitor different types of cell-based assays non-invasively and label-free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedical research. The author, Maximilian Oberleitner, describes approaches in which the cells are directly grown on different sensor surfaces (gold-film electrodes, shear wave resonators or dye-doped polymer films). This approach, with the reacting cells in particularly close proximity and contact with the sensor surface, is key to a remarkable sensitivity, opening the way for a variety of new applications. This thesis not only introduces the fundamentals of each approach, but it also describes in great detail the design principles and elucidates the boundary conditions of the new sensors.

Cold atmospheric plasma (CAP) emerges as a possible new modality for cancer treatment. This book provides a comprehensive introduction into fundamentals of the CAP and plasma devices used in plasma medicine. An analysis of the mechanisms of plasma interaction with cancer and normal cells including description of possible mechanisms of plasma selectivity is included. Recent advances in the field, the primary challenges and future directions are presented.

This thesis focuses on the very high Mach number shock wave that is located sunward of Saturn's strong magnetic field in the continuous high-speed flow of charged particles from the Sun (the solar wind). The author exploits the fact that the Cassini spacecraft is the only orbiter in a unique parameter regime, far different from the more familiar near-Earth space, to provide in-situ insights into the unreachable exotic regime of supernova remnants. This thesis bridges the gap between shock physics in the Solar System and the physics of ultra-high Mach number shocks around the remnants of supernova explosions, since to date research into the latter has been restricted to theory, remote observations, and simulations.

This is the first book in the series to focus on dynamic hyperpolarized nuclear magnetic resonance, a burgeoning topic in biophysics. The volume follows the format and style of the Handbook of Modern Biophysics series and expands on topics already discussed in previous volumes. It builds a theoretical and experimental framework for students and researchers who wish to investigate the biophysics and biomedical application of dynamic hyperpolarized NMR. All contributors are internationally recognized experts, lead the dynamic hyperpolarized NMR field, and have first-hand knowledge of the chapter material. The book covers the following topics: Hyperpolarization by dissolution Dynamic Nuclear Polarization Design considerations for implementing a hyperpolarizer Chemical Shift Imaging with Dynamic Hyperpolarized NMR Signal Sampling Strategies in Dynamic Hyperpolarized NMR Kinetic Modeling of Enzymatic Reactions in Analyzing Hyperpolarized NMR Data Using Hyperpolarized NMR to Understand Biochemistry from Cells to Humans Innovating Metabolic Biomarkers for Hyperpolarized NMR New Insights into Metabolic Regulation from Hyperpolarized 13C MRS/MRI Studies Novel Views on Heart Function from Dynamic Hyperpolarized NMR Insights on Lactate Metabolism in Skeletal Muscle based on 13C Dynamic Nuclear Polarization Studies About the Editors Dirk Mayer is Professor of Diagnostic Radiology and Nuclear Medicine at the University of Maryland and is the Director of Metabolic Imaging. He is a recognized expert on dynamic nuclear polarization (DNP) MRI-based imaging techniques and has optimized acquisition and reconstruction techniques, has constructed kinetic modeling for quantitative analysis, and has developing new probes. Thomas Jue is Professor of Biochemistry and Molecular Medicine at the University of California Davis. He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo. He served as a Chair of the Biophysics Graduate Group Program at UC Davis, where he started to redesign a graduate curriculum that balances physical science/mathematics formalism and biomedical perspective in order to promote interest at the interface of physical science, engineering, mathematics, biology, and medicine. The Handbook of Modern Biophysics represents an aspect of that effort.