Recent discoveries in astronomy and relativistic astrophysics as well as experiments on particle and nuclear physics have blurred the traditional boundaries of physics. It is believed that at the birth of the Universe, a whirlwind of matter and antimatter, of quarks and exotic leptons, briefly appeared and merged into a sea of energy. The new phenomena and new states of matter in the Universe revealed the deep connection between quarks and the Cosmos. Motivated by these themes, this book discusses different topics: gravitational waves, dark matter, dark energy, exotic contents of compact stars, high-energy and gamma-ray astrophysics, heavy ion collisions and the formation of the quark-gluon plasma in the early Universe. The book presents some of the latest researches on these fascinating themes and is useful for experts and students in the field.

The clinical use of Artificial Intelligence (AI) in radiation oncology is in its infancy. However, it is certain that AI is capable of making radiation oncology more precise and personalized with improved outcomes. Radiation oncology deploys an array of state-of-the-art technologies for imaging, treatment, planning, simulation, targeting, and quality assurance while managing the massive amount of data involving therapists, dosimetrists, physicists, nurses, technologists, and managers. AI consists of many powerful tools which can process a huge amount of inter-related data to improve accuracy, productivity, and automation in complex operations such as radiation oncology.This book offers an array of AI scientific concepts, and AI technology tools with selected examples of current applications to serve as a one-stop AI resource for the radiation oncology community. The clinical adoption, beyond research, will require ethical considerations and a framework for an overall assessment of AI as a set of powerful tools.30 renowned experts contributed to sixteen chapters organized into six sections: Define the Future, Strategy, AI Tools, AI Applications, and Assessment and Outcomes. The future is defined from a clinical and a technical perspective and the strategy discusses lessons learned from radiology experience in AI and the role of open access data to enhance the performance of AI tools. The AI tools include radiomics, segmentation, knowledge representation, and natural language processing. The AI applications discuss knowledge-based treatment planning and automation, AI-based treatment planning, prediction of radiotherapy toxicity, radiomics in cancer prognostication and treatment response, and the use of AI for mitigation of error propagation. The sixth section elucidates two critical issues in the clinical adoption: ethical issues and the evaluation of AI as a transformative technology.

Advanced fiber materials have been developed for various superior applications because of their higher mechanical flexibility, high-temperature resistance, and outstanding chemical stability. This book presents an overview of the current development of advanced fiber materials, fabrication methods, and applications. Applications covered include pollution control, environment, energy, information storage technology, optical and photonic, photocatalysis, textile, drug delivery, tumor therapy, corrosion protection applications, and a state of art of advanced fiber materials.

Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.

With the rapid growth of new evidence from astronomy, space science and biology that supports the theory of life as a cosmic rather than terrestrial phenomenon, this book discusses a set of crucial data and pictures showing that life is still arriving at our planet. Although it could spark controversy among the most hardened sceptics this book will have an important role in shaping future science in this area.

This book is an introduction to the mechanical properties, the force generating capacity, and the sensitivity to mechanical cues of the biological system. To understand how these qualities govern many essential biological processes, we also discuss how to measure them. However, before delving into the details and the techniques, we will first learn the operational definitions in mechanics, such as force, stress, elasticity, viscosity and so on. This book will explore the mechanics at three different length scales - molecular, cellular, and tissue levels - sequentially, and discuss the measurement techniques to quantify the intrinsic mechanical properties, force generating capacity, mechanoresponsive processes in the biological systems, and rupture forces.

Bringing his cosmic perspective to civilization on Earth, Neil deGrasse Tyson, bestselling author of Astrophysics for People in a Hurry, shines new light on the crucial fault lines of our time-war, politics, religion, truth, beauty, gender, race, and tribalism-in a way that stimulates a deeper sense of unity for us all. In a time when our political and cultural perspectives feel more divisive than ever, Tyson provides a much-needed antidote to so much of what divides us, while making a passionate case for the twin engines of enlightenment-a cosmic perspective and the rationality of science. After thinking deeply about how a scientist views the world and about what Earth looks like from space, Tyson has found that terrestrial thoughts change as our brain resets and recalibrates life's priorities, along with the actions we might take in response. As a result, no outlook on culture, society, or civilisation remains untouched. In Starry Messenger, Tyson reveals just how human the enterprise of science is. Far from a cold, unfeeling undertaking, scientific methods, tools, and discoveries have shaped modern civilisation and created the landscape we've built for ourselves on which to live, work, and play. Tyson shows how an infusion of science and rational thinking renders worldviews deeper and more informed than ever before-and exposes unfounded perspectives and unjustified emotions. With crystalline prose and an abundance of evidence, Starry Messenger walks us through the scientific palette that sees and paints the world differently. From lessons on resolving global conflict to reminders of how precious it is to be alive, Tyson reveals, with warmth and eloquence, ten surprising, brilliant, and beautiful truths of human society, informed and enlightened by knowledge of our place in the universe.

There are reasons to believe the 21st century will be the best ever for astrophysics: the James Webb Space Telescope will extend nearly twenty times the present observational limit of visible light; neutrino massiveness opens a new window for exploration on dark energy and dark matter physics and is expected to provide insights into the fate of the Universe; the Higgs boson may allow for an understanding of the weakness of gravity; gravitational waves produced at the birth of the Universe and by compact stellar objects (supermassive black holes, black hole/neutron star mergers, gamma-ray bursts, white dwarf inspirals) have unveiled a new area of astronomy. Against this background, compact stars, the theme of this volume, present unique astrophysical laboratories for probing the fabric of space-time and the building blocks of matter and their interactions at physical regimes not attainable in terrestrial laboratories.

Leonhard Euler's Letters to a German Princess: A Milestone in the History of Physics Textbooks and More is a milestone in the history of physics textbooks and the instruction of women in the sciences. It also covers views of its author on epistemology, religion, and innovations in scientific equipment, including telescopes and microscopes. Today, 250 years later, we study this work of Euler's as a foundation for the history of physics teaching and analyze the letters from an historical and pedagogical point of view.

In this book, cancer theranostics applications of magnetic iron oxide nanoparticles are overviewed in details. Moreover, their synthesis, characterization, multifunctionality, disease targeting, biodistribution, pharmacokinetics and toxicity have been briefly highlighted. Finally, we have mentioned the current examples of clinical trials of magnetic nanoparticles in cancer theranostics along with their future scopes and challenges.

This book begins with the history and fundamentals of optical fiber communications. Then, briefly introduces existing optical multiplexing techniques and finally focuses on spatial domain multiplexing (SDM), aka space division multiplexing, and orbital angular momentum of photon based multiplexing. These are two emerging multiplexing techniques that have added two new degrees of photon freedom to optical fibers.

Nanomedicine is a developing field, which includes different disciplines such as material science, chemistry, engineering and medicine devoted to the design, synthesis and construction of high-tech nanostructures. The ability of these structures to have their chemical and physical properties tuned by structural modification, has allowed their use in drug delivery systems, gene therapy delivery, and various types of theranostic approaches. Colloidal noble metal nanoparticles and other nanostructures have many therapeutic and diagnostic applications. The concept of drug targeting as a magic bullet has led to much research in chemical modification to design and optimize the binding to targeted receptors. It is important to understand the precise relationship between the drug and the carrier and its ability to target specific tissues, and pathogens to make an efficient drug delivery system. This book covers advances based on different drug delivery systems: polymeric and hyper branched nanomaterials, carbon-based nanomaterials, nature-inspired nanomaterials, and pathogen-based carriers.

In the field of astrophysics, modern developments of practice are emerging in order to further understand the spectral information derived from cosmic sources. Radio telescopes are a current mode of practice used to observe these occurrences. Despite the various accommodations that this technology offers, physicists around the globe need a better understanding of the underlying physics and operational components of radio telescopes as well as an explanation of the cosmic objects that are being detected. Analyzing the Physics of Radio Telescopes and Radio Astronomy is an essential reference source that discusses the principles of the astronomical instruments involved in the construction of radio telescopes and the analysis of cosmic sources and celestial objects detected by this machinery. Featuring research on topics such as electromagnetic theory, antenna design, and geometrical optics, this book is ideally designed for astrophysicists, engineers, researchers, astronomers, students, and educators seeking coverage on the operational methods of radio telescopes and understanding the physical processes of radio astronomy.

The world of single-board computing puts powerful coding tools in the palm of your hand. The portable Raspberry Pi computing platform with the power of Linux yields an exciting exploratory tool for beginning scientific computing. Science and Computing with Raspberry Pi takes the enterprising researcher, student, or hobbyist through explorations in a variety of computing exercises with the physical sciences. The book has tutorials and exercises for a wide range of scientific computing problems while guiding the user through: Configuring your Raspberry Pi and Linux operating system Understanding the software requirements while using the Pi for scientific computing Computing exercises in physics, astronomy, chaos theory, and machine learning

NMR spectroscopy has found a wide range of applications in life sciences over recent decades. Providing a comprehensive amalgamation of the scattered knowledge of how to apply high-resolution NMR techniques to biomolecular systems, this book will break down the conventional stereotypes in the use of NMR for structural studies. The major focus is on novel approaches in NMR which deal with the functional interface of either protein-protein interactions or protein-lipid interactions. Bridging the gaps between structural and functional studies, the Editors believe a thorough compilation of these studies will open an entirely new dimension of understanding of crucial functional motifs. This in turn will be helpful for future applications into drug design or better understanding of systems. The book will appeal to NMR practitioners in industry and academia who are looking for a comprehensive understanding of the possibilities of applying high-resolution NMR spectroscopic techniques in probing biomolecular interactions.

This book demonstrates Microsoft EXCEL-based Fourier transform of selected physics examples. Spectral density of the auto-regression process is also described in relation to Fourier transform. Rather than offering rigorous mathematics, readers will "try and feel" Fourier transform for themselves through the examples. Readers can also acquire and analyze their own data following the step-by-step procedure explained in this book. A hands-on acoustic spectral analysis can be one of the ideal long-term student projects.