SINGLE SOURCE GUIDE TO PEROXIDASES AND CATALASES

Reflecting the important historical discoveries and exciting research in the field in recent years, "Peroxidases and Catalases: Biochemistry, Biophysics, Biotechnology and Physiology" provides a much-needed systematic, up-to-date treatment of peroxidases and catalases.

From the structure and properties of the various superfamilies to current applications of peroxidases, the book consolidates vast amounts of information previously scattered in the professional literature, covering all aspects of these ubiquitous enzymes that act on a variety of substances and processes in living systems--their properties, reactions, crystal structures, cloning, and more.

Considering the subject from both theoretical and applied perspectives, "Peroxidases and Catalases" offers a critical review of the literature and detailed discussions of the most current research. Chapters cover:

The background and history of peroxidases and catalases

Plant, fungal, and bacterial peroxidase superfamilies and their organization

Mammalian peroxidases including medical and physiological roles

Spectroscopic and theoretical techniques for studying peroxidases highlighting the contributions of physicists and physical/theoretical chemists

Heme peroxidases, catalases, and other peroxidases such as vanadium and selenium peroxidase

Relevant plant and animal physiology

This one-stop reference is a vital reference for biochemists, biologists, biochemical engineers, physiologists, environmental and pharmaceutical researchers, and others interested in the study and use of peroxidases and catalases.

This book examines the origins and dynamical characteristics of atmospheric inertia-gravity waves in the Antarctic mesosphere. Gravity waves are relatively small-scale atmospheric waves with a restoring force of buoyancy that can transport momentum upward from the troposphere to the middle atmosphere. In previous studies, the dynamical characteristics of mesospheric gravity waves have not been fully examined using numerical simulations, since performing a numerical simulation with a high resolution and a high model-top requires considerable computational power. However, recent advances in computational capabilities have allowed us to perform numerical simulations using atmospheric general circulation models, which cover the troposphere to the mesosphere with a sufficiently fine horizontal resolution to resolve small-scale gravity waves. The book first describes the simulation of mesospheric gravity waves using a high-resolution non-hydrostatic atmospheric model with a high model top. The accuracy of the numerical results was confirmed by the first Mesosphere-Stratosphere-Troposphere/Incoherent Scattering (MST/IS) radar observation in the Antarctic. It also depicts the origins and propagation processes of mesospheric gravity waves on the basis of the results of the high-resolution numerical model. The behaviors of mesospheric gravity waves can be clearly explained using both fundamental and cutting-edge theories of fluid dynamics

Have you ever wondered what comets are and why astronomers spend so much time studying them? Now, a comet expert and an astronomical historian have come together to produce this unique book. Using their several decades of teaching experience, the authors have concisely presented the information you need to comprehend these majestic apparitions that grace our night skies. No mathematical proficiency is needed. In fact, this book doesn't contain a single equation. Comets are cosmic Rosetta stones, bridging our current knowledge by digging back to the earliest days of our solar systems. How did life arise on Earth? Did comets play a significant role in bringing water and the necessary organic matter to our early Earth? How about the dinosaurs? Were they driven to extinction by a cometary impact 66 million years ago? Comets may be both the enablers and destroyers of life on Earth as we know it. These are some of the tantalizing questions discussed here. If you so desire, steps are given to join the ranks of amateur comet hunters. Astronomy is one of the last sciences where amateurs play a significant role. Your reward for discovery? A comet officially bearing your name in the history books. The next great comet is on its way, we just do not know when it will arrive. Armed with this book, you will be ready to enjoy this unforgettable event.

All living matter is comprised of cells; small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are a single cell and all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all its cells and organs fulfilling their roles. The aim of this book is to investigate the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that, in turn, leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goal of every cell is to stay alive and to fulfil its function as a part of a larger organ or organism. This first volume is an inventory of physical transport processes occurring in cells, while the second volume will take a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Since the publication of the best-selling, highly acclaimed first edition, the technology and clinical applications of medical imaging have changed significantly. Gathering these developments into one volume, Webb s Physics of Medical Imaging, Second Edition presents a thorough update of the basic physics, modern technology and many examples of clinical application across all the modalities of medical imaging.

New to the Second Edition

• Extensive updates to all original chapters
• Coverage of state-of-the-art detector technology and computer processing used in medical imaging
• 11 new contributors in addition to the original team of authors
• Two new chapters on medical image processing and multimodality imaging
• More than 50 percent new examples and over 80 percent new figures
• Glossary of abbreviations, color insert and contents lists at the beginning of each chapter

Keeping the material accessible to graduate students, this well-illustrated book reviews the basic physics underpinning imaging in medicine. It covers the major techniques of x-radiology, computerised tomography, nuclear medicine, ultrasound and magnetic resonance imaging, in addition to infrared, electrical impedance and optical imaging. The text also describes the mathematics of medical imaging, image processing, image perception, computational requirements and multimodality imaging. "

Gene therapy as a potential method for the treatment of genetic disorders and other malignancies, as well as the treatment of many cancers, has attracted a great amount of attention in recent years. Current research focuses on stable and smart drug/gene-delivery systems, including controlled release. Nanoparticle (NP)-Based Delivery Vehicles looks at smart nanostructures and how these are considered a promising approach when applied to drug- and gene-delivery systems, in addition to how to solve the problems related to the inefficient transfer of medication to the affected cells.

Advancement in the field of nanotechnology has revolutionized the field of medicines and pharmaceuticals in the 20th century. The proper use of nanomaterials in medical applications requires a proper understanding of these compounds. This correct understanding, beyond the physical and chemical properties, must also have the correct logic of use. In other words, the strategic use of nanomaterials with applicable perspective can also help to advance research, but if we go forward with the current research perspective that leads to the expansion of inapplicable researches, the intrinsic importance of using these nanomaterials is eliminated. This book, considering the importance of nanomaterials and their application in medicine, as well as the significant growth of biomaterials in research fields, introduces the variables law (Rabiee's theory) for the implementation of this research and the establishment of a proper strategy. It should be noted that in addition to observing biocompatibility tests for a biomaterial based on existing protocols and standards, the Applicable Compatibility (AC) parameter is also required in accordance with Rabiee's theory. This book is written in accordance with Rabiee's theory and the contents of this book should be evaluated from this perspective.

This book provides a concise introduction to the special theory of relativity and the general theory of relativity. The format has been chosen to provide the basis for a single semester course that can take the students all the way from the foundations of special relativity to the core results of general relativity: the Einstein equation, and the equations of motion for particles and light in curved spacetime. To facilitate access to the topics of special and general relativity for science and engineering students, without prior training in relativity or geometry, the relevant geometric notions are also introduced.

This book describes in detail the various theories on the shape of the Earth from classical antiquity to the present day and examines how measurements of its form and dimensions have evolved throughout this period. The origins of the notion of the sphericity of the Earth are explained, dating back to Eratosthenes and beyond, and detailed attention is paid to the struggle to establish key discoveries as part of the cultural heritage of humanity. In this context, the roles played by the Catholic Church and the philosophers of the Middle Ages are scrutinized. Later contributions by such luminaries as Richer, Newton, Clairaut, Maupertuis, and Delambre are thoroughly reviewed, with exploration of the importance of mathematics in their geodetic enterprises. The culmination of progress in scientific research is the recognition that the reference figure is not a sphere but rather a geoid and that the earth's shape is oblate. Today, satellite geodesy permits the solution of geodetic problems by means of precise measurements. Narrating this fascinating story from the very beginning not only casts light on our emerging understanding of the figure of the Earth but also offers profound insights into the broader evolution of human thought.

Comprehensive and up-to-date information on Earth's most dominant year-to-year climate variation The El Nino Southern Oscillation (ENSO) in the Pacific Ocean has major worldwide social and economic consequences through its global scale effects on atmospheric and oceanic circulation, marine and terrestrial ecosystems, and other natural systems. Ongoing climate change is projected to significantly alter ENSO's dynamics and impacts. El Nino Southern Oscillation in a Changing Climate presents the latest theories, models, and observations, and explores the challenges of forecasting ENSO as the climate continues to change. Volume highlights include: Historical background on ENSO and its societal consequences Review of key El Nino (ENSO warm phase) and La Nina (ENSO cold phase) characteristics Mathematical description of the underlying physical processes that generate ENSO variations Conceptual framework for understanding ENSO changes on decadal and longer time scales, including the response to greenhouse gas forcing ENSO impacts on extreme ocean, weather, and climate events, including tropical cyclones, and how ENSO affects fisheries and the global carbon cycle Advances in modeling, paleo-reconstructions, and operational climate forecasting Future projections of ENSO and its impacts Factors influencing ENSO events, such as inter-basin climate interactions and volcanic eruptions The American Geophysical Union promotes discovery in Earth and space science for the benefit of humanity. Its publications disseminate scientific knowledge and provide resources for researchers, students, and professionals. Find out more about this book from this Q&A with the editors.

This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.

This book describes the life, times and science of the Soviet physicist Lev Vasilevich Shubnikov (1901-1937). From 1926 to 1930 Shubnikov worked in Leiden where he was the co-discoverer of the Shubnikov-De Haas effect. After his return to the Soviet Union he founded in Kharkov in Ukraine the first low-temperature laboratory in the Soviet Union, which in a very short time became the foremost physics institute in the country and among other things led to the discovery of type-II superconductivity. In August 1937 Shubnikov, together with many of his colleagues, was arrested and shot early in November 1937. This gripping story gives deep insights into the pioneering work of Soviet physicists before the Second World War, as well as providing much previously unpublished information about their brutal treatment at the hands of the Stalinist regime.

Cold atmospheric plasma (CAP) emerges as a possible new modality for cancer treatment. This book provides a comprehensive introduction into the fundamentals of the CAP and plasma devices used in plasma medicine. An analysis of the mechanisms of plasma interaction with cancer and normal cells, including a description of possible mechanisms of plasma selectivity, is included. Recent advances in the field, the primary challenges and future directions are also presented.

Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production. This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases.

Machine Learning Techniques for Space Weather provides a thorough and accessible presentation of machine learning techniques that can be employed by space weather professionals. Additionally, it presents an overview of real-world applications in space science to the machine learning community, offering a bridge between the fields. As this volume demonstrates, real advances in space weather can be gained using nontraditional approaches that take into account nonlinear and complex dynamics, including information theory, nonlinear auto-regression models, neural networks and clustering algorithms. Offering practical techniques for translating the huge amount of information hidden in data into useful knowledge that allows for better prediction, this book is a unique and important resource for space physicists, space weather professionals and computer scientists in related fields.

Statistical Postprocessing of Ensemble Forecasts brings together chapters contributed by international subject-matter experts describing the current state of the art in the statistical postprocessing of ensemble forecasts. The book illustrates the use of these methods in several important applications including weather, hydrological and climate forecasts, and renewable energy forecasting. After an introductory section on ensemble forecasts and prediction systems, the second section of the book is devoted to exposition of the methods available for statistical postprocessing of ensemble forecasts: univariate and multivariate ensemble postprocessing are first reviewed by Wilks (Chapters 3), then Schefzik and Moeller (Chapter 4), and the more specialized perspective necessary for postprocessing forecasts for extremes is presented by Friederichs, Wahl, and Buschow (Chapter 5). The second section concludes with a discussion of forecast verification methods devised specifically for evaluation of ensemble forecasts (Chapter 6 by Thorarinsdottir and Schuhen). The third section of this book is devoted to applications of ensemble postprocessing. Practical aspects of ensemble postprocessing are first detailed in Chapter 7 (Hamill), including an extended and illustrative case study. Chapters 8 (Hemri), 9 (Pinson and Messner), and 10 (Van Schaeybroeck and Vannitsem) discuss ensemble postprocessing specifically for hydrological applications, postprocessing in support of renewable energy applications, and postprocessing of long-range forecasts from months to decades. Finally, Chapter 11 (Messner) provides a guide to the ensemble-postprocessing software available in the R programming language, which should greatly help readers implement many of the ideas presented in this book. Edited by three experts with strong and complementary expertise in statistical postprocessing of ensemble forecasts, this book assesses the new and rapidly developing field of ensemble forecast postprocessing as an extension of the use of statistical corrections to traditional deterministic forecasts. Statistical Postprocessing of Ensemble Forecasts is an essential resource for researchers, operational practitioners, and students in weather, seasonal, and climate forecasting, as well as users of such forecasts in fields involving renewable energy, conventional energy, hydrology, environmental engineering, and agriculture.

Complexity of Seismic Time Series: Measurement and Application applies the tools of nonlinear dynamics to seismic analysis, allowing for the revelation of new details in micro-seismicity, new perspectives in seismic noise, and new tools for prediction of seismic events. The book summarizes both advances and applications in the field, thus meeting the needs of both fundamental and practical seismology. Merging the needs of the classical field and the very modern terms of complexity science, this book covers theory and its application to advanced nonlinear time series tools to investigate Earth's vibrations, making it a valuable tool for seismologists, hazard managers and engineers.

Indian Shield: Precambrian Evolution and Phanerozoic Reconstitution highlights unique evolutionary trends covering a period of over 3,500 million years, from the oldest crust to the most recent geological activity of the Indian Subcontinent. The book discusses regional terrain geology in terms of the evolutionary history of the crust, describing how the Precambrian Shield evolved from a stable continental region to a tectonically unstable zone marked by frequent high-intensity earthquakes in a Plate-interior setting. It is a complete and readable account of the history of growth and evolution of the Indian Subcontinent, including Bangladesh, Bhutan, India, Nepal and Pakistan. The book is intended for graduate students, researchers, and teachers in the geosciences, especially geophysics, geomorphology and geology. The book also serves as an important resource for tectonics and petrology researchers, as well as those involved in exploration of mineral resources.

This book addresses the mechanism of enrichment of heavy elements in galaxies, a long standing problem in astronomy. It mainly focuses on explaining the origin of heavy elements by performing state-of-the-art, high-resolution hydrodynamic simulations of dwarf galaxies. In this book, the author successfully develops a model of galactic chemodynamical evolution by means of which the neutron star mergers can be used to explain the observed abundance pattern of the heavy elements synthesized by the rapid neutron capture process, such as europium, gold, and uranium in the Local Group dwarf galaxies. The book argues that heavy elements are significant indicators of the evolutionary history of the early galaxies, and presents theoretical findings that open new avenues to understanding the formation and evolution of galaxies based on the abundance of heavy elements in metal-poor stars.