Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of pharmacology, biochemistry, cell and molecular biology, chemistry, immunology, neurobiology, immunology, nutrition sciences, drug development and the clinical management of both acute and chronic diseases.

The monograph introduces the reader to the world of inductive well logging - an established method for surveying the electrical conductivity of rocks surrounding a borehole. The emphasis is on developing a theory of inductive logging and on understanding logging tools basic physics, since this theory and understanding furnish valuable insights for inventing practical induction logging techniques.

The first chapter of the book presents the basic laws of electromagnetism from a point of view that will facilitate the application of the theory to problems in electromagnetic logging. Many topics that play an important role in the design and interpretation of tools readings are covered. The vertical resolution and radial depth of investigation of different induction tools is systematically considered. Special attention is paid to principles of induction logging with transversal induction coils, to transient method of induction logging in media with cylindrical and horizontal interfaces and to the influence of anisotropy on the electromagnetic field measured in a conducting medium. Multi-coil differential induction probes and induction logging based on measuring the inphase component of the secondary field or the quadrature component difference are also described in detail. The last chapter is devoted to mathematical modeling of the response of induction logging tools in 3D geometries. The theory of inductive logging presented in this volume can be applied to logging after drilling as well as logging while drilling.

This informative publication brings together knowledge of various aspects of cellular regulation. Current Topics in Cellular Regulation reviews the progress being made in those specialized areas of study that have undergone substantial development. It also publishes provocative new theories and concepts and serves as a forum for the discussion of general principles. Researchers in cellular regulation as well as biochemists, molecular and cell biologists, microbiologists, and biophysicists will find Current Topics in Cellular Regulation a useful source of up-to-date information.
Key Features
* Regulation of Iron Metabolism in Eukaryotes
* Regulation of Fas-Mediated Apoptosis
* Aging and Regulation of Apoptosis
* Regulation of Bacterial Responses of Oxidaditive Stress
* Regulation of NF-(B and Disease Control
* Mechanism and Regulation of Bone Resorption
* Gene Regulation by Reactive Oxygen Species
* Structure, Mechanism, and Specificity of Protein-Tyrosine Phosphatases

At the heart of this book is the generalized theoretical approach that is applied to investigate the geoelectrical structure of the Earth's mantle. It also analyzes the results of regional and global induction sounding of the Earth's mantle and compares them with the results obtained by other geophysical methods. The generalized theoretical approach employs the Induction Law as a basis for identifying extended relations between magnetic field components, including their plane divergence, impedances and spatial derivatives. The estimations of impedance values and spatial derivatives are performed using the theory of stochastic processes. The book also considers the external sources of magnetic fields used for sounding the Earths mantle from the modern theory perspective, as well as the problem of coincidence of magneto-variation and magnetotelluric methods. Further, it discusses secular variations in the Earth's resistance caused by non-induction sources, factors that are correlated with the number of earthquakes in the region and shifted in time with global indexes. It is a valuable resource for scientists applying deep induction soundings or interested in the structures of and processes in the Earth's interior.

This book explores the dynamics of planetary and stellar fluid layers, including atmospheres, oceans, iron cores, and convective and radiative zones in stars, describing the different theoretical, computational and experimental methods used to study these problems in fluid mechanics, including the advantages and limitations of each method for different problems. This scientific domain is by nature interdisciplinary and multi-method, but while much effort has been devoted to solving open questions within the various fields of mechanics, applied mathematics, physics, earth sciences and astrophysics, and while much progress has been made within each domain using theoretical, numerical and experimental approaches, cross-fertilizations have remained marginal. Going beyond the state of the art, the book provides readers with a global introduction and an up-to-date overview of relevant studies, fully addressing the wide range of disciplines and methods involved. The content builds on the CISM course "Fluid mechanics of planets and stars", held in April 2018, which was part of the research project FLUDYCO, supported by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program.

This book highlights a major advance in low-energy scattering theory: the Multi-Channel Algebraic Scattering (MCAS) theory, which represents an attempt to unify structure and reaction theory. It solves the Lippmann-Schwinger equations for low-energy nucleon-nucleus and alpha-nucleus scattering in momentum space, allowing both the bound and scattering states in the compound nucleus formed to be described. Results of various cases are presented and discussed.

Advances in Microbial Physiology, Volume 70 continues the long tradition of topical, important, cutting-edge reviews in microbiology with this new volume covering a variety of topics, including Bacterial Hemoprotein Sensors of NO: H-NOX and NosP, Manganese in Marine Microbiology, Nutritional Immunity and Fungal Pathogenesis: The Struggle for Micronutrients at the Host-Pathogen Interface, Metal-Based Combinations that Target Protein Synthesis by Fungi, Transition Metal Homeostasis in Streptococcus Pyogenes and Streptococcus Pneumoniae, Copper and Antibiotics: Discovery, Modes of Action, and Opportunities for Medicinal Applications, Metal Resistance and Its Association with Antibiotic Resistance, and The Role of Intermetal Competition and Mis-Metalation in Metal Toxicity.

It's happening now-plans are being formulated under the coordination of NASA to launch a permanent, manned space station by the year 1990. Studies surveying user requirements, system attributes, and architectural options have been conducted, and you're on the top of these far-reaching considerations on the next big step taken within space! Now that the Shuttle and Spacelab are realities, NASA has set sights on a new horizon-a permanent, manned space station in the high frontier. The precedents have been set-Skylab hosted human visits for up to 84 days, and the Soviet's Salyut was and is a temporary base for cosmonaut crew. The differences are the term and scope of space station living and the accomplishments that can be realized with a permanent site and continuous experimentation within its facilities. Brian O'Leary, writer, astrophysicist, and former astronaut, describes the "tinkermodules" that will be carried to the earth's orbit to be assembled as a space station. His inside track information also lay

Mass human migrations into outer space may begin this century! Are Earth's inhabitants prepared for this next giant leap? Millions of tax dollars are being employed in NASA and Defense Department research facilities to answer this urgent question. Can humankind migrate to space intelligently, in a civilized manner without real Star Wars? Are these justifiable economic, political, and philosophical reasons for undertaking such a vast project? What legal and institutional implications will surface in distinguishing Earthkind from Spacekind? The immediate and long-range effects of space migration-on earth and its inhabitants, on the solar system and its pioneers-are brought into sharp focus here, within the perspective of the heated debates now taking place in the highest government, scientific, business, and academic circles. From the development of the space shuttle Enterprise and the uses and objectives of the Space Transportation System to the U.S. and Soviet space arsenals of hunter-killer satellites and

Conducting and semiconducting (conjugated) polymers have a unique set of properties, combining the electronic properties of metals and semiconductors with the processing advantages and mechanical properties of polymers. Now, thirty-five years after their discovery, metallic conducting polymers have been demonstrated in the laboratory to have electrical conductivities approaching that of copper, and mechanical strengths exceeding that of steel, a remarkable achievement. A wide variety of electrical and optical devices have been demonstrated using semiconducting polymers. Light-emitting devices have been made which are as bright as fluorescent lamps at applied voltages of only a few volts; photovoltaic solar energy conversion using conjugated polymer composites is in industrial production; conjugated polymer transistors, circuits and chips have been demonstrated. Indeed, semiconducting and metallic polymers can be thought of as electronic 'inks'. The advances in printing technology (ink-jet printing, off-set printing, etc) combined with the science and technology of conducting polymers will revolutionize the way in which electronic devices are manufactured. In addition, semiconducting and metallic polymers can be used in applications which require special mechanical properties such as flexibility. The field of semiconducting and conducting polymers has become one of the most attractive areas of interdisciplinary materials science and technology. Ranging from physics, chemistry, electrical and electronic engineering to the optical sciences, this field covers a wide range of competences and interdisciplinary knowledge.

The prospectus of humans living, working, and establishing communities in space can no longer be dismissed as the romantic notions of science fiction writers and space buffs. With the launch of the space shuttle human kind will enter a new era in space exploration, one giant step closer to the goal of human colonization. Our understanding of man's role in space is maturing, and the myths of life in space as a slick Buck Rogers episode or a scene from Star Wars must give way to a realistic plan for human life in other part of the solar system. We are ready now for a factual assessment of the challenges ahead: in Toward Distant Suns, the prospects of space exploration and space colonization have come of age. Here, for the first time, is a realistic look at what humankind must accomplish in order to colonize near space. Based on the most up-to-date research available, Toward Distant Suns tackles the problems of technology and lifestyle that will face those men and women whose mission is to settle space. Here is realistic, in-depth coverage of: space shuttle's role in near space construction, development of new, more versatile rocket fuels and motors, building the large communications platforms, power satellites the "Space Spider," and space colonies, the space workers-how they will be chosen, trained, and transported; life in zero-g-space tourism and space war; "suburbanizing" space earth dwellers; the real future of interstellar colonization. Toward Distant Suns also takes a new look at the tantalizing question: What is our place in the galaxy? It reviews the Search for Extraterrestrial Intelligence experiments, the latest work on interstellar flight and colonization, and the current scientific information on planetary formation and humanoid development, to reach the startling conclusion: Mankind may be unique and along.

Praise for the Series:
"Timely...High standard of Writing...It is to be highly recommended."
--Quarterly Journal of Experimental Physiology
This informative publication brings together knowledge of various aspects of cellular regulation. Current Topics in Cellular Regulation reviews the progress being made in those specialized areas of study that have undergone substantial development. It also publishes provocative new theories and concepts and serves as a forum for the discussion of general principles.
Researchers in cellular regulation as well as biochemists, molecular and cell biologists, microbiologists, biophysicists, physiologists, nutritionists, and pathologists will find Current Topics in Cellular Regulation a useful source of up-to-date information.

* CONTENTS: Regulatory Features of Multicatalytic and 26S Proteases. Calponin. Type III Cyclic Nucelotide Phosphodiesterases and Insulin Action. Mammalian Aminoacyl-tRNA Synthetases. Regulation of Interaction between Signaling Protein CheY and Flagellar Motor during Bacterial Chemotaxis. The Chemical Biology of Nitric Oxide: Regulation and Protective and Toxic Mechanisms. Nutritional and Hormonal Regulation of Glutathione Homeostasis. Protein Folding and Association: In Vitro Studies for Self Organization and Targeting in the Cell.

This monograph traces the development of our understanding of how and where energetic particles are accelerated in the heliosphere and how they may reach the Earth. Detailed data sets are presented which address these topics. The bulk of the observations are from spacecraft in or near the ecliptic plane. It is timely to present this subject now that Voyager-1 has entered the true interstellar medium. Since it seems unlikely that there will be a follow-on to the Voyager programme any time soon, the data we already have regarding the outer heliosphere are not going to be enhanced for at least 40 years.

These proceedings present selected research papers from CSNC2017, held during 23th-25th May in Shanghai, China. The theme of CSNC2017 is Positioning, Connecting All. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC2017, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.

This volume offers an overview of the state-of-the-art theoretical and practical approaches currently used for geophysical data interpretation. It includes new methods and techniques for solving data processing problems, and an analysis of geopotential fields by international researchers. It discusses topics such as: 1. Theoretical issues of interpretation of gravitational, magnetic and electric fields, including general methods of interpreting potential fields and other geophysical data. 2. Modern algorithms and computer technologies for interpretating geophysical fields. 3. The study of Earth deep structure using terrestrial and satellite potential field anomalies. 4. Geological interpretation of gravitational, magnetic and electric fields. This proceedings book is of interest to all geophysical researchers.

This book focuses on skin photoaging, the premature aging of skin due to environmental effects such as exposure to UV (UVA, UVB) radiation from the sun.

An Introduction to Mining Seismology describes comprehensively the modern methods and techniques used to monitor and study seismicity and rockbursts in mines. Key case histories from various worldwide mining districts clearly illustrate and skillfully emphasize the practical aspects of mining seismology. This text is intended as a handbook for geophysicists and mining and rock mechanics engineers working at mines. It will also serve as an essential reference tool for seismologists working at research institutions on local seismicity not necessarily induced by mining.
Key Features
* Presents a comprehensive description of seismicity induced by mining worldwide
* Provides information on optimum network planning and seismic event location procedures in deep mines
* Covers a broad array of topics including focal mechanism, moment tensor, and double-couple versus non-double-couple seismic events in mines
* Includes data on source parameters and scaling relations for seismic events in mines

The authors of this volume have been intimately connected with the conception of Big Bang model since 1947. They present a picture of what is now believed to be state-of-the-art knowledge about the evolution of the expanding universe and delineate the story of the development of the Big Bang model as they have seen and lived it from their own unique vantage point.

This thesis presents a pioneering method for gleaning the maximum information from the deepest images of the far-infrared universe obtained with the Herschel satellite, reaching galaxies fainter by an order of magnitude than in previous studies. Using these high-quality measurements, the author first demonstrates that the vast majority of galaxy star formation did not take place in merger-driven starbursts over 90% of the history of the universe, which suggests that galaxy growth is instead dominated by a steady infall of matter. The author further demonstrates that massive galaxies suffer a gradual decline in their star formation activity, providing an alternative path for galaxies to stop star formation. One of the key unsolved questions in astrophysics is how galaxies acquired their mass in the course of cosmic time. In the standard theory, the merging of galaxies plays a major role in forming new stars. Then, old galaxies abruptly stop forming stars through an unknown process. Investigating this theory requires an unbiased measure of the star formation intensity of galaxies, which has been unavailable due to the dust obscuration of stellar light.

This book highlights how the properties and structure of materials are affected by dynamic high pressures generated by explosions, projectile impacts, laser compression, electric discharge or ball milling. Starting with the basics of shock-wave physics and an outline of experimental techniques, it then surveys dynamic compressibility and equations of state of various substances, phase transitions and syntheses of novel compounds under shock. It covers various industrial applications including hardening of metals and grinding (fragmentation) of solids, saturation of solids with defects for use as catalysts, production of superhard materials (synthetic diamond, BN (boron nitride)) and nanomaterials, especially nanodiamond, and discusses state-of-the-art techniques such as combining dynamic and static compression to obtain monolithic materials.

This book introduces readers to MesoBioNano (MBN) Explorer - a multi-purpose software package designed to model molecular systems at various levels of size and complexity. In addition, it presents a specially designed multi-task toolkit and interface - the MBN Studio - which enables the set-up of input files, controls the simulations, and supports the subsequent visualization and analysis of the results obtained. The book subsequently provides a systematic description of the capabilities of this universal and powerful software package within the framework of computational molecular science, and guides readers through its applications in numerous areas of research in bio- and chemical physics and material science - ranging from the nano- to the mesoscale. MBN Explorer is particularly suited to computing the system's energy, to optimizing molecular structure, and to exploring the various facets of molecular and random walk dynamics. The package allows the use of a broad variety of interatomic potentials and can, e.g., be configured to select any subset of a molecular system as rigid fragments, whenever a significant reduction in the number of dynamical degrees of freedom is required for computational practicalities. MBN Studio enables users to easily construct initial geometries for the molecular, liquid, crystalline, gaseous and hybrid systems that serve as input for the subsequent simulations of their physical and chemical properties using MBN Explorer. Despite its universality, the computational efficiency of MBN Explorer is comparable to that of other, more specialized software packages, making it a viable multi-purpose alternative for the computational modeling of complex molecular systems. A number of detailed case studies presented in the second part of this book demonstrate MBN Explorer's usefulness and efficiency in the fields of atomic clusters and nanoparticles, biomolecular systems, nanostructured materials, composite materials and hybrid systems, crystals, liquids and gases, as well as in providing modeling support for novel and emerging technologies. Last but not least, with the release of the 3rd edition of MBN Explorer in spring 2017, a free trial version will be available from the MBN Research Center website (mbnresearch.com).

This book provides detailed calculated values for the thermal radiative and thermodynamic functions of black-body radiation in finite spectral ranges. The results are presented in tabular form. The areas of thermal power generation, infrared medical diagnostics, solar power and nuclear generation, and astrophysics are included. A range of the thermal radiative and thermodynamic functions are calculated by the authors in the finite frequency/wavenumber/wavelength intervals at different temperatures. This book also contains the tables of the chromaticity coordinates and RGB parameters calculated for different color spaces (Rec.709 (HDTV), sRGB, Adobe RGB). A number of the optimization problems is formulated and solved for various thermal black-body radiative and thermodynamic functions in a finite range of frequencies.

The focus of this book is the remarkable advances in understanding of low pressure RF (radio frequency) glow discharges. A basic analytical theory and plasma physics are explained. Plasma diagnostics are also covered before the practicalities of etcher use are explored.

How to Understand Quantum Mechanics presents an accessible introduction to understanding quantum mechanics in a natural and intuitive way, which was advocated by Erwin Schroedinger and Albert Einstein. A theoretical physicist reveals dozens of easy tricks that avoid long calculations, makes complicated things simple, and bypasses the worthless anguish of famous scientists who died in angst. The author's approach is light-hearted, and the book is written to be read without equations, however all relevant equations still appear with explanations as to what they mean. The book entertainingly rejects quantum disinformation, the MKS unit system (obsolete), pompous non-explanations, pompous people, the hoax of the 'uncertainty principle' (it is just a math relation), and the accumulated junk-DNA that got into the quantum operating system by misreporting it. The order of presentation is new and also unique by warning about traps to be avoided, while separating topics such as quantum probability to let the Schroedinger equation be appreciated in the simplest way on its own terms. This is also the first book on quantum theory that is not based on arbitrary and confusing axioms or foundation principles. The author is so unprincipled he shows where obsolete principles duplicated basic math facts, became redundant, and sometimes were just pawns in academic turf wars. The book has many original topics not found elsewhere, and completely researched references to original historical sources and anecdotes concerting the unrecognized scientists who actually did discover things, did not all get Nobel prizes, and yet had interesting productive lives.