Pulsar timing is a promising method for detecting gravitational waves in the nano-Hertz band. In his prize winning Ph.D. thesis Rutger van Haasteren deals with how one takes thousands of seemingly random timing residuals which are measured by pulsar observers, and extracts information about the presence and character of the gravitational waves in the nano-Hertz band that are washing over our Galaxy. The author presents a sophisticated mathematical algorithm that deals with this issue. His algorithm is probably the most well-developed of those that are currently in use in the Pulsar Timing Array community. In chapter 3, the gravitational-wave memory effect is described. This is one of the first descriptions of this interesting effect in relation with pulsar timing, which may become observable in future Pulsar Timing Array projects. The last part of the work is dedicated to an effort to combine the European pulsar timing data sets in order to search for gravitational waves. This study has placed the most stringent limit to date on the intensity of gravitational waves that are produced by pairs of supermassive black holes dancing around each other in distant galaxies, as well as those that may be produced by vibrating cosmic strings. Rutger van Haasteren has won the 2011 GWIC Thesis Prize of the Gravitational Wave International Community for his innovative work in various directions of the search for gravitational waves by pulsar timing. The work is presented in this Ph.D. thesis.

Integrating basic to applied science and technology in medicine, pharmaceutics, molecular biology, biomedical engineering, biophysics and irreversible thermodynamics, this book covers cutting-edge research of the structure and function of biomaterials at a molecular level. In addition, it examines for the first time studies performed at the nano- and micro scale. With innovative technologies and methodologies aiming to clarify the molecular mechanism and macroscopic relationship, Nano/Micro Science and Technology in Biorheology thoroughly covers the basic principles of these studies, with helpful step-by-step explanations of methodologies and insight into medical applications. Written by pioneering researchers, the book is a valuable resource for academics and industry scientists, as well as graduate students, working or studying in bio-related fields.

This book provides results of analysis of typical solar events, statistical analysis, the diagnostics of energetic electrons and magnetic field, as well as the global behavior of solar flaring loops such as their contraction and expansion. It pays particular attention to analyzing solar flare loops with microwave, hard X-ray, optical and EUV emissions, as well as the theories of their radiation, and electron acceleration/transport. The results concerning influence of the pitch-angle anisotropy of non-thermal electrons on their microwave and hard X-ray emissions, new spectral behaviors in X-ray and microwave bands, and results related to the contraction of flaring loops, are widely discussed in the literature of solar physics. The book is useful for graduate students and researchers in solar and space physics.

Although the origin and the basic meaning of the terms "planar lipid bilayers" and "liposome" have not changed during the years, the present advances in the scientific, technological, biomedical and consumer product fields are remarkable. Ever since its launch the "Advances in Planar Lipid Bilayers and Liposomes' (APLBL) has provided a global platform for a community of researchers having very broad scientific interests in theoretical, experimental and simulation studies on lipid and cell membrane micro and nanostructures. Ranging from artificial lipid membranes to cell membranes, controlled release of functional molecules, drug delivery to cancer cells, pharmaceutical formulations to food products, the applications are simply enormous. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.

This book presents the state-of-the-art of optical remote sensing applied for the generation of marine climate-quality data products, with contributions by international experts in the field. The chapters are logically grouped into six thematic parts, each introduced by a brief overview. The different parts include: i. requirements for the generation of climate data records from satellite ocean measurements and additionally basic radiometry principles addressing terminology, standards, measurement equation and uncertainties; ii. satellite visible and thermal infrared radiometry embracing instrument design, characterization and, pre- and post-launch calibration; iii. in situ visible and thermal infrared radiometry including overviews on basic principles, technology and measurements methods required to support satellite missions devoted to climate change investigations; iv. simulations as fundamental tools to support interpretation and analysis of both in situ and satellite radiometric measurements; v. strategies for in situ radiometry to satisfy mission requirements for the generation of climate data records; and finally, vi. methods for the assessment of satellite data products. Fundamentals of measurement theory are taken through to implementation of practical ground based radiometers and their application to validate satellite data used to generate climate data records. This book presents practical solutions for those involved or contemplating the validation of optical climate measurements from satellite instruments.

This thesis presents theoretical and numerical studies on phenomenological description of the quark gluon plasma (QGP), a many-body system of elementary particles.

The author formulates a causal theory of hydrodynamics for systems with net charges from the law of increasing entropy and a momentum expansion method. The derived equation results can be applied not only to collider physics, but also to the early universe and ultra-cold atoms.

The author also develops novel off-equilibrium hydrodynamic models for the longitudinal expansion of the QGP on the basis of these equations. Numerical estimations show that convection and entropy production during the hydrodynamic evolution are key to explaining excessive charged particle production, recently observed at the Large Hadron Collider. Furthermore, the analyses at finite baryon density indicate that the energy available for QGP production is larger than the amount conventionally assumed. "

This thesis highlights data from MINOS, a long-baseline accelerator neutrino experiment, and details one of the most sensitive searches for the sterile neutrino ever made. Further, it presents a new analysis paradigm to enable this measurement and a comprehensive study of the myriad systematic uncertainties involved in a search for a few-percent effect, while also rigorously investigating the statistical interpretation of the findings in the context of a sterile neutrino model. Among the scientific community, this analysis was quickly recognized as a foundational measurement in light of which all previous evidence for the sterile neutrino must now be (re)interpreted. The existence of sterile neutrinos has long been one of the key questions in the field. Not only are they a central component in many theories of new physics, but a number of past experiments have yielded results consistent with their existence. Nonetheless, they remain controversial: the interpretation of the data showing evidence for these sterile neutrinos is hotly debated.

Brownian diffusion is the motion of one or more solute molecules in a sea of very many, much smaller solvent molecules. Its importance today owes mainly to cellular chemistry, since Brownian diffusion is one of the ways in which key reactant molecules move about inside a living cell. This book focuses on the four simplest models of Brownian diffusion: the classical Fickian model, the Einstein model, the discrete-stochastic (cell-jumping) model, and the Langevin model. The authors carefully develop the theories underlying these models, assess their relative advantages, and clarify their conditions of applicability. Special attention is given to the stochastic simulation of diffusion, and to showing how simulation can complement theory and experiment. Two self-contained tutorial chapters, one on the mathematics of random variables and the other on the mathematics of continuous Markov processes (stochastic differential equations), make the book accessible to researchers from a broad spectrum of technical backgrounds.

This book offers review chapters written by invited speakers of the 3rd Session of the Sant Cugat Forum on Astrophysics - Gravitational Waves Astrophysics. All chapters have been peer reviewed. The book goes beyond normal conference proceedings in that it provides a wide panorama of the astrophysics of gravitational waves and serves as a reference work for researchers in the field.

Order from chaos is simultaneously a mantra of physics and a reality in biology. Physicist Norman Packard suggested that life developed and thrives at the edge of chaos. Questions remain, however, as to how much practical knowledge of biology can be traced to existing physical principles, and how much physics has to change in order to address the complexity of biology. Phil Anderson, a physics Nobel laureate, contributed to popularizing a new notion of the end of "reductionism." In this view, it is necessary to abandon the quest of reducing complex behavior to known physical results, and to identify emergent behaviors and principles. In the present book, however, we have sought physical rules that can underlie the behavior of biota as well as the geochemistry of soil development. We looked for fundamental principles, such as the dominance of water flow paths with the least cumulative resistance, that could maintain their relevance across a wide range of spatial and temporal scales, together with the appropriate description of solute transport associated with such flow paths. Thus, ultimately, we address both nutrient and water transport limitations of processes from chemical weathering to vascular plant growth. The physical principles guiding our effort are established in different, but related concepts and fields of research, so that in fact our book applies reductionist techniques guided by analogy. The fact that fundamental traits extend across biotic and abiotic processes, i.e., the same fluid flow rate is relevant to both, but that distinctions in topology of the connected paths lead to dramatic differences in growth rates, helps unite the study of these nominally different disciplines of geochemistry and geobiology within the same framework. It has been our goal in writing this book to share the excitement of learning, and one of the most exciting portions to us has been the ability to bring some order to the question of the extent to which soils can facilitate plant growth, and what limitations on plant sizes, metabolism, occurrence, and correlations can be formulated thereby. While we bring order to the soil constraints on growth , we also generate some uncertainties in the scaling relationships of plant growth and metabolism. Although we have made an first attempt to incorporate edaphic constraints into allometric scaling, this is but an initial foray into the forest.

Our understanding of the rheological and seismic properties of the Earth's interior relies on interpreting geophysical observations using mineral physics data. The complexity of natural materials complicates these interpretations, but here the key features of such materials in controlling the attenuation of seismic waves are determined by a set of careful experiments. This thesis clearly explains how dynamic mechanical spectroscopy has been used to determine the visco-elastic properties of igneous and sedimentary rocks containing geological fluids. These experiments highlight, for the first time, the importance of mineral and rock microstructures as controls on geophysical properties of solids, particularly near the melting point. The results have impacts in areas ranging from volcanic processes, through the structure of the deep Earth, to fluid-saturated porous media.

In this thesis, ultimate sensitive measurement for weak force imposed on a suspended mirror is performed with the help of a laser and an optical cavity for the development of gravitational-wave detectors. According to the Heisenberg uncertainty principle, such measurements are subject to a fundamental noise called quantum noise, which arises from the quantum nature of a probe (light) and a measured object (mirror). One of the sources of quantum noise is the quantum back-action, which arises from the vacuum fluctuation of the light. It sways the mirror via the momentum transferred to the mirror upon its reflection for the measurement. The author discusses a fundamental trade-off between sensitivity and stability in the macroscopic system, and suggests using a triangular cavity that can avoid this trade-off. The development of an optical triangular cavity is described and its characterization of the optomechanical effect in the triangular cavity is demonstrated. As a result, for the first time in the world the quantum back-action imposed on the 5-mg suspended mirror is significantly evaluated. This work contributes to overcoming the standard quantum limit in the future.

Advances in Quantum Chemistry presents surveys of current topics in this rapidly developing field that has emerged at the cross section of the historically established areas of mathematics, physics, chemistry, and biology. It features detailed reviews written by leading international researchers. This volume focuses on thetheory of heavy ion physics in medicine.

This volume presents a series of articles concerning current important topics in quantum chemistry. The invited articles are written by the best people in the field."

This book presents a study of the saturation of unstable f-modes (fundamental modes) due to low-order nonlinear mode coupling. Since their theoretical prediction in 1934, neutron stars have remained among the most challenging objects in the Universe. Gravitational waves emitted by unstable neutron star oscillations can be used to obtain information about their inner structure, that is, the equation of state of dense nuclear matter. After its initial growth phase, the instability is expected to saturate due to nonlinear effects. The saturation amplitude of the unstable mode determines the detectability of the generated gravitational-wave signal, but also affects the evolution of the neutron star. The study shows that the unstable (parent) mode resonantly couples to pairs of stable (daughter) modes, which drain the parent's energy and make it saturate via a mechanism called parametric resonance instability. Further, it calculates the saturation amplitude of the most unstable f-mode multipoles throughout their so-called instability windows.

This book consists of invited reviews written by world-renowned experts on the subject of the outskirts of galaxies, an upcoming field which has been understudied so far. These regions are faint and hard to observe, yet hide a tremendous amount of information on the origin and early evolution of galaxies. They thus allow astronomers to address some of the most topical problems, such as gaseous and satellite accretion, radial migration, and merging. The book is published in conjunction with the celebration of the end of the four-year DAGAL project, an EU-funded initial training network, and with a major international conference on the topic held in March 2016 in Toledo. It thus reflects not only the views of the experts, but also the scientific discussions and progress achieved during the project and the meeting. The reviews in the book describe the most modern observations of the outer regions of our own Galaxy, and of galaxies in the local and high-redshift Universe. They tackle disks, haloes, streams, and accretion as observed through deep imaging and spectroscopy, and guide the reader through the various formation and evolution scenarios for galaxies. The reviews focus on the major open questions in the field, and explore how they can be tackled in the future. This book provides a unique entry point into the field for graduate students and non-specialists, and serves as a reference work for researchers in this exciting new field.

This authoritative volume explores advances in the techniques used to measure percutaneous penetration of drugs and chemicals to assess bioavailability and bioequivalence and discusses how they have been used in clinical and scientific investigations. Seven comprehensive sections examine topics including in vitro drug release, topical drugs products, clinical studies, and guidelines and workshop reports, among others. The book also describes how targeted transdermal drug delivery and more sophisticated mathematical modelling can aid in understanding the bioavailability of transdermal drugs. The first edition of this book was an important reference guide for researchers working to define the effectiveness and safety of drugs and chemicals that penetrated the skin. This second edition contains cutting-edge advances in the field and is a key resource to those seeking to define the bioavailability and bioequivalence of percutaneously active compounds to improve scientific and clinical investigation and regulation.

This book reviews and assesses the various methodologies for site characterization and site effect estimation to carry out seismic zonation at micro and macro levels. Readers will learn about the suitability of these methodologies for each level of zoning that needs to be assessed in order to optimize the resources for carrying out seismic zonation. The Indian sub-continent is highly vulnerable to earthquake hazards, and past studies have focused primarily on the Himalayan region (inter-plate zone) and the northeast region (subduction zone). The book improves understanding of the Peninsular India that also has significantly high seismicity and is prone to earthquakes of sizeable magnitude. Particular attention is given to the various methodologies for assessing seismic hazards, the scales at which site characterizations are carried out, and optimal methods for zonation practices using site data and hazard indexes. Aimed at students, this book will be of use to post-graduates and doctoral students researching seismic zonation, hazard assessment and mitigation, and spatial data in earth sciences.

Beyond enabling new capabilities, plasma-based techniques, characterized by quantum radicals of feed gases, hold the potential to enhance and improve many processes and applications. Following in the tradition of its popular predecessor, Plasma Electronics, Second Edition: Applications in Microelectronic Device Fabrication explains the fundamental physics and numerical methods required to bring these technologies from the laboratory to the factory. Emphasizing computational algorithms and techniques, this updated edition of a popular monograph supplies a complete and up-to-date picture of plasma physics, computational methods, applications, and processing techniques. Reflecting the growing importance of computer-aided approaches to plasma analysis and synthesis, it showcases recent advances in fabrication from micro- and nano-electronics, MEMS/NEMS, and the biological sciences. A helpful resource for anyone learning about collisional plasma structure, function, and applications, this edition reflects the latest progress in the quantitative understanding of non-equilibrium low-temperature plasma, surface processing, and predictive modeling of the plasma and the process. Filled with new figures, tables, problems, and exercises, it includes a new chapter on the development of atmospheric-pressure plasma, in particular microcell plasma, with a discussion of its practical application to improve surface efficiency. The book provides an up-to-date discussion of MEMS fabrication and phase transition between capacitive and inductive modes in an inductively coupled plasma. In addition to new sections on the phase transition between the capacitive and inductive modes in an ICP and MOS-transistor and MEMS fabrications, the book presents a new discussion of heat transfer and heating of the media and the reactor. Integrating physics, numerical methods, and practical applications, this book equips you with the up-to-date understanding required to scale up lab breakthroughs into industrial innovations.

This thesis considers the non-equilibrium and energy transfer processes involved in the evolution of astrophysical gases and plasmas. Momentum-energy transfer in collisions of atoms, molecules and ions governs the evolution of interacting astrophysical gas and plasmas. These collisions require an accurate quantum mechanical description and the work presented here develops a unified kinetic and quantum-mechanical model for this consideration. The multi-scale computational approach implemented here takes into account non-thermal distributions of atomic particles and clarifies their role in the evolution of interstellar gas and planetary atmospheres. As shown, the physical parameters of non-thermal distributions strongly depend on the differential cross sections of atomic, molecular and ion collisions. Readers will find a detailed description of the energy relaxation of energetic atoms, produced in the interstellar gas by the solar and stellar wind plasmas. Computation of the non-thermal diffuse background of energetic helium atoms in the heliosphere is also included for evaluation of the contributions from local and cosmic sources and analysis of related satellite observations. Work involving modeling of energetic particle precipitation into planetary atmospheres and formation of the planetary and exoplanetary escape fluxes has been performed with very accurate cross sections, describing momentum-energy transfer processes with high precision. Results of the Monte Carlo simulations, carried out for the Mars atmosphere at different solar conditions, can be used for analysis of observational data for Mars atmospheric escape and investigation into the history of Martian water.

The search for gravitational radiation with optical interferometers is gaining momentum worldwide. Beside the VIRGO and GEO gravitational wave observatories in Europe and the two LIGOs in the United States, which have operated successfully during the past decade, further observatories are being completed (KAGRA in Japan) or planned (ILIGO in India). The sensitivity of the current observatories, although spectacular, has not allowed direct discovery of gravitational waves. The advanced detectors (Advanced LIGO and Advanced Virgo) at present in the development phase will improve sensitivity by a factor of 10, probing the universe up to 200 Mpc for signal from inspiraling binary compact stars. This book covers all experimental aspects of the search for gravitational radiation with optical interferometers. Every facet of the technological development underlying the evolution of advanced interferometers is thoroughly described, from configuration to optics and coatings and from thermal compensation to suspensions and controls. All key ingredients of an advanced detector are covered, including the solutions implemented in first-generation detectors, their limitations, and how to overcome them. Each issue is addressed with special reference to the solution adopted for Advanced VIRGO but constant attention is also paid to other strategies, in particular those chosen for Advanced LIGO.

This series of reference books describes the sciences of different fields in and around geodesy. Each chapter, is written by experts in the respective fields and covers an individual field and describes the history, theory, the objective, the technology, and the development, the highlight of the research, the applications, the problems, as well as future directions. Contents of Volume II include: Geodetic LEO Satellite Missions, Satellite Altimetry, Airborne Lidar, GNSS Software Receiver, Geodetic Boundary Problem, GPS and INS, VLBI, Geodetic Reference Systems, Spectral Analysis, Earth Tide and Ocean Loading Tide, Remote Sensing, Photogrammetry, Occultation, Geopotential Determination, Geoid Determination, Local Gravity Field, Geopotential Determination, Magnet Field, Mobile Mapping, General Relativity, Wide-area Precise Positioning etc.

Transport phenomena in porous media continues to be a field which attracts intensive research activity. This is primarily due to the fact that it plays an important and practical role in a large variety of diverse scientific applications. "Transport Phenomena in Porous Media II" covers a wide range of the engineering and technological applications, including both stable and unstable flows, heat and mass transfer, porosity, and turbulence.

"Transport Phenomena in Porous Media II" is the second volume in a series emphasising the fundamentals and applications of research in porous media. It contains 16 interrelated chapters of controversial, and in some cases conflicting, research, over a wide range of topics. The first volume of this series, published in 1998, met with a very favourable reception. "Transport Phenomena in Porous Media II" maintains the original concept including a wide and diverse range of topics, whilst providing an up-to-date summary of recent research in the field by its leading practitioners.

Authored by a world-renowned aerial photography and remote sensing expert, "Geographic Aerial Photography: Identifying Earth-Surface Hazards Through Image Interpretation "is" "the most practical and authoritative reference available for any professional or student looking for a reference on how to recognize, analyze, interpret and avoid or successfully plan for dangerous contingencies.

Whether they are related to natural terrain, geology, vegetation, hydrology or land use patterns it s critical for you to be able to recognize dangerous conditions when and where they exist. Failure to adequately recognize and characterize geomorphic, geologic, and hydrologic dangers on the ground using aerial photography is one of the major factors contributing to due to natural hazards and disasters, damage to architectural structures, and often the subsequent loss of human life as a result. Aerial photographs provide one of the most prevalent, inexpensive and under-utilized tools to those with the knowledge and expertise to interpret them.

Authored by one of the world s experts in aerial photography and remote sensing, with more than 35 years of experience in research and instruction. Features more than 100 color photographs to vividly explore the fundamental principles of aerial photography. Chapter tables underscore key concepts including channel size and shape characteristics, image scales, reverse fault values, and strike-slip fault systems."