Albert Einstein's General Theory of Relativity, published in 1915, made a remarkable prediction: gravitational radiation. Just like light (electromagnetic radiation), gravity could travel through space as a wave and affect any objects it encounters by alternately compressing and expanding them. However, there was a problem. The force of gravity is around a trillion, trillion, trillion times weaker than electromagnetism so the calculated compressions and expansions were incredibly small, even for gravity waves resulting from a catastrophic astrophysical event such as a supernova explosion in our own galaxy. Discouraged by this result, physicists and astronomers didn't even try to detect these tiny, tiny effects for over 50 years. Then, in the late 1960s and early 1970s, two events occurred which started the hunt for gravity waves in earnest. The first was a report of direct detection of gravity waves thousands of times stronger than even the most optimistic calculation. Though ultimately proved wrong, this result started scientists thinking about what instrumentation might be necessary to detect these waves. The second was an actual, though indirect, detection of gravitational radiation due to the effects it had on the period of rotation of two 'neutron stars' orbiting each other. In this case, the observations were in exact accord with predictions from Einstein's theory, which confirmed that a direct search might ultimately be successful. Nevertheless, it took another 40 years of development of successively more sensitive detectors before the first real direct effects were observed in 2015, 100 years after gravitational waves were first predicted. This is the story of that hunt, and the insight it is producing into an array of topics in modern science, from the creation of the chemical elements to insights into the properties of gravity itself.

"Advances in Imaging and Electron Physics" merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy." This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.
* Updated with contributions from leading international scholars and industry experts
* Discusses hot topic areas and presents current and future research trends
* Invaluable reference and guide for physicists, engineers and mathematicians

In 1988, in an article on the analysis of the measurements of the variations in the radial velocities of a number of stars, Campbell, Walker, and Yang reported an - teresting phenomenon;the radial velocity variations of Cephei seemed to suggest the existence of a Jupiter-like planet around this star. This was a very exciting and, at the same time, very surprising discovery. It was exciting because if true, it would have marked the detection of the ?rst planet outside of our solar system. It was surprising because the planet-hosting star is the primary of a binary system with a separation less than 19 AU, a distance comparable to the planetary distances in our solar system. The moderatelyclose orbit of the stellar companionof Cephei raised questions about the reality of its planet. The skepticism over the interpretation of the results (which was primarily based on the idea that binary star systems with small sepa- tions would not be favorable places for planet formation) became so strong that in a subsequent paper in 1992, Walker and his colleagues suggested that the planet in the Cephei binary might not be real, and the variations in the radial velocity of this star might have been due to its chromospheric activities.

In this thesis single-molecule fluorescence resonance energy transfer (FRET) spectroscopy was used to study the folding of a protein that belongs to the large and important family of repeat proteins. Cohen shows that the dynamics of the expanded conformations is likely to be very fast, suggesting a spring-like motion of the whole chain. The findings shed new light on the elasticity of structure in repeat proteins, which is related to their function in binding multiple and disparate partners. This concise research summary provides useful insights for students beginning a PhD in this or a related area, and researchers entering this field.

This book focuses on the recent progress in nanophotonics technology to be used to develop novel nano-optical devices, fabrication technology, and security systems. It begins with a review of the concept of dressed photons and applications to devices, fabrication, and systems; principles and applications. Further topics include: DNA process for quantum dot chain, photon enhanced emission microscopy, near field spectroscopy of metallic nanostructure, self-organized fabrication of composite semiconductor quantum dots, formation of metallic nanostructure, and nanophotonic information systems with security. These topics are reviewed by seven leading scientists. This overview is a variable resource for engineers and scientists working in the field of nanophotonics.

Seismic waves generated by earthquakes have been interpreted to provide us information about the Earth s structure across a variety of scales. For short periods of less than 1 second, the envelope of seismograms changes significantly with increased travel distance and coda waves are excited by scattering due to randomly distributed heterogeneities in the Earth. Deterministic structures such as horizontally uniform velocity layer models in traditional seismology cannot explain these phenomena. This book focuses on the Earth heterogeneity and scattering effects on seismic waves. Topics covered are recent developments in wave theory and observation including: coda wave analysis for mapping medium heterogeneity and monitoring temporal variation of physical properties, radiation of short-period seismic waves from an earthquake fault, weak localization of seismic waves, attenuation of seismic waves in randomly porous media, synthesis of seismic wave envelopes in short periods, and laboratory investigations of ultrasonic wave propagation in rock samples.

*Understanding new methods for the analysis of short-period seismic waves to characterize the random heterogeneity of the Earth on many scales.
*Observations of seismic wave scattering. Discussion of techniques for mapping medium heterogeneity and for monitoring temporal change in medium characteristics.
* Up-to-date techniques for the synthesis of wave envelopes in random media."

This volume documents the contributions presented at the Seventh Scientific Meeting of the Spanish Astronomical Society (Sociedad Espanola de Astronomia, SEA). The event bought together 301 participants who presented 161 contributed talks and 120 posters, the greatest numbers up to now. The fact that most exciting items of the current astronomical research were addressed in the meeting proofs the good health of the SEA, a consolidated organization founded fifteen years ago in Barcelona. Two plenary sessions of the meeting were devoted to the approved entrance of Spain as a full member of the European Southern Observatory (ESO) and to the imminent first light of the greatest telescope in the world, the GTC (Gran Telescopio de Canarias), milestones that will certainly lead the Spanish Astronomy in the next future."

The Second Edition of The Drift of Sea Ice presents the fundamental laws of sea ice drift which come from the material properties of sea ice and the basic laws of mechanics. The resulting system of equations is analysed for the general properties of sea ice drift, the free drift model and analytical models for ice drift in the presence of internal friction, and the construction of numerical ice drift models is detailed. This second edition of a much lauded work, unique on this topic in the English language, has been revised, updated and expanded with much new information and outlines recent results, in particular in relation to the climate problem, mathematical modelling and ice engineering applications.

The current book presents the theory, observations, mathematical modelling techniques, and applications of sea ice drift science. The theory is presented from the beginning on a graduate student level, so that students and researchers coming from other fields such as physical oceanography, meteorology, physics, engineering, environmental sciences or geography can use the book as a source book or self-study material. First the drift ice material is presented ending with the concept of ice state the relevant properties in sea ice dynamics. Ice kinematics observations are widely presented with the mathematical analysis methods, and thereafter come drift ice rheology to close the triangle material kinematics stress. The momentum equation of sea ice is derived in detail and its general properties are carefully analysed. Then follow two chapters on analytical models: free drift and drift in the presence of internal friction: These are very important tools in understanding the dynamical behaviour of sea ice. The last topical chapter is numerical models, which are the modern tool to solve ice dynamics problem in short term and long term problems. The closing chapter summarises sea ice dynamics applications and the need of sea ice dynamic knowledge and gives some final remarks on the future of this branch of science.

This book on pressure-induced phase transitions in AB2X4 chalcogenide compounds deals with one important AmBnXp material. The interest in these materials is caused by their properties. The results are discussed for three main groups of structural families: cubic-spinel structures, defective tetragonal structures, and other structures like layered and wurtzite-type modifications. A systematic analysis of the behavior of cubic (spinel), tetragonal (defect chalcopyrites and stannites) and other crystal modifications of AB2X4 compounds under hydrostatic pressure is performed. The behavior of AIIAl2S4, AIIGa2S4, AIIAl2Se4 and AIIGa2Se4 compounds with defective tetragonal structures, compounds with layered and wurtzite structures under hydrostatic pressure and the pressure dependence of the band gap, lattice parameters, interatomic distances, vibrational modes and pressure-induced phase transitions is discussed. Many of these compounds, except oxide spinels, undergo a pressure-induced phase transition towards the rocksalt-type structure. The phase transition is preceded by disorder in the cation sublattice. The dependence of the transition pressure to the rocksalt-type structure as a function of the compound ionicity and the size criterion is analyzed. At high pressures, all ordered-vacancy compounds are found to exhibit a band anticrossing between several conduction bands that leads to a strong decrease of its pressure coefficient and consequently to a strong non-linear pressure dependence of the direct bandgap energy. Theoretical studies of phase transitions in several ordered-vacancy compounds reveal that the existence of ordered vacancies alter the cation-anion bond distances and their compressibilities. The book is written for students, Ph D. students and specialists in materials science, phase transitions and new materials.

"Mechanobiology of Cell-Matrix Interactions" focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.

This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter. Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions. Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.

It all began with Markus Jochum approaching one of us (HvS) - "when you guys are doing interviews with senior scientists from oceanography and related sciences, why are you not doing Walter Munk?" Indeed, why not? Walter Munk, an icon in oceanography, had just given a wonderful talk in a symposium in honor of his 90th birthday, sweeping a grand circle from his earliest work with Chip Cox on airborne measurements of ocean surface roughness to the latest satellite data - not simply a review, but the struggle of an active scientist opening up new perspectives - as inspiring and stimulating as when one of us (KH) rst met him at the Ocean Waves Conference in Easton in 1961 (Fig. I. 1). Walter immediately agreed to share with us his recollections on the nearly seventy years of his path-breaking contributions in a sheer amazing range of topics, from ocean waves, internal waves, ocean currents, tides, tsunamis, sea level, microseisms and the rotation of the earth to ocean acoustic tomography. With "you guys" Markus was referring to HvS and the various partners HvS had 1 invited to join him in conducting a series of interviews of retired colleagues.

The fourth edition of SEG's best seller is a valuable, comprehensive reference that is a must for every geophysicist, geologist, explorationist, engineer, energy adviser, economist, editor, and student involved in the field. Hundreds of terms have been added since publication of the third edition in 1991, reflecting rapid evolution of the science, especially in the areas of engineering and production problems, 3D (including multicomponent) acquisition and processing, visualization, S- and converted waves, interpretation, anisotropy, AVO, geostatistics, geohazards, neural networks, tomography, downhole measurements, horizontal drilling, and deepwater work. Definitions of hundreds of other terms have been updated. The dictionary's title has been modified slightly to reflect growth in application of geophysical methods, with the word Applied replacing the word Exploration. The dictionary includes a guide to pronunciation and a list of reference figures and tables. A CD containing the dictionary in searchable PDF format also is included.

Astronomical jets are key astrophysical phenomena observed in gamma-ray bursts, active galactic nuclei or young stars. Research on them has largely occurred within the domains of astronomical observations, astrophysical modeling and numerical simulations, but the recent advent of high energy density facilities has added experimental control to jet studies.

Front-line research on jet launching and collimation requires a highly interdisciplinary approach and an elevated level of sophistication. Bridging the gaps between pure magnetohydrodynamics, thermo-chemical evolution, high angular resolution spectro-imaging and laboratory experiments is no small matter. This volume strives to bridge those very gaps. It offers a series of lectures which, taken as whole, act as a thorough reference for the foundations of this discipline. These lectures address the following:

- laboratory jets physics from laser and z-pinch plasma experiments,
- the magnetohydrodynamic theory of relativistic and non-relativistic stationary jets,
- heating mechanisms in magnetohydrodynamic jets, from the solar magnetic reconnection to the molecular shock heating perspectives,
- atomic and molecular microphysics of jet shocked material.

In addition to the lectures, the book offers, in closing, a presentation of a series of observational diagnostics, thus allowing for the recovery of basic physical quantities from jet emission lines.

This book covers topics on mechanosensing, mechanotransduction, and actin cytoskeletal dynamics in cell motility. It will contribute to a better understanding of how cells functionally adapt to their mechanical environment as well as highlighting fundamental concepts for designing material niches for cell manipulation. With topics from multidisciplinary fields of the life sciences, medicine and engineering, the book is the first of its kind, providing comprehensive, integrated coverage of innovative approaches to cell biomechanics. It provides a valuable resource for seniors and graduate students studying cell biomechanics and is also suitable for researchers interested in the application of methods and strategies in connection with the innovative approaches discussed. Each section of the book has been supplemented with concrete examples and illustrations to facilitate understanding even for readers unfamiliar with cell biomechanics.

This thesis sheds new light on the worldwide first electrical manipulation of a single nuclear spin. Over the last four decades, the size of a bit, the smallest logical unit in a computer, has decreased by more than two orders of magnitude and will soon reach a limit where quantum phenomena become important. Inspired by the power of quantum mechanics, researchers have already identified pure quantum systems, having, analog to a classical bit, two controllable and readable states. In this regard, the inherent spin of electrons or nuclei with its two eigenstates, spin up and spin down, is a promising candidate. Using expertise in the field of single-molecule magnets, the author developed a molecular transistor, which allows quantum information to be written onto a single nuclear spin by means of an electric field only, and, in addition, enables the electronic read-out of this quantum state. This novel approach opens a path to addressing and manipulating individual nuclear spins within a very confined space (a single molecule), at high speed. Thus, the author was able to show that single molecule magnets are promising candidates for quantum information processing, which is triggering a new field of research towards molecular quantum electronics.

This volume is a collection of articles from the ISSBMR 7th Course: Structure and Biophysics - New Technologies for Current Challenges in Biology and Beyond. This NATO Advanced Institute (ASI) was held at the Ettore Majorana Foundation and Centre for Scientific Culture in Sicily. The ASI brought together a diverse group of experts in the fields of Structural Biology, Biophysics and Physics. Prominent lecturers, from seven different countries, and students from around the world participated. The session addressed the treatment and detection of bioterrorism agents, and focused on critical partner country priorities in biotechnology, materials and drug discovery. The range of topics represents the diversity of critical problems between structural biology, biochemistry and biophysics, in which lies the fertile ground of drug development, biotechnology and new materials.

This book provides an introduction to the physics of interstellar gas in the Galaxy. It deals with the diffuse interstellar medium which supplies a complex environment for exploring the neutral gas content of a galaxy like the Milky Way and the techniques necessary for studying this non-stellar component. After an initial exposition of the phases of the interstellar medium and the role of gas in a spiral galaxy, the authors discuss the transition from atomic to molecular gas. They then consider basic radiative transfer and molecular spectroscopy with particular emphasis on the molecules useful for studying low-density molecular gas. Observational techniques for investigating the gas and the dust component of the diffuse interstellar medium throughout the electromagnetic spectrum are explored emphasizing results from the recent Herschel and Planck missions. A brief exposition on dust in the diffuse interstellar medium is followed by a discussion of molecular clouds in general and high-latitude molecular clouds in particular. Ways of calibrating CO observations with the molecular hydrogen content of a cloud are examined along with the dark molecular gas controversy. High-latitude molecular clouds are considered in detail as vehicles for applying the techniques developed in the book. Given the transient nature of diffuse and translucent molecular clouds, the role of turbulence in the origin and dynamics of these objects is examined in some detail. The book is targeted at graduate students or postdocs who are entering the field of interstellar medium studies.

This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.

This book on multiscale seismic tomography, written by one of the leaders in the field, is suitable for undergraduate and graduate students, researchers, and professionals in Earth and planetary sciences who need to broaden their horizons about seismotectonics, volcanism, and interior structure and dynamics of the Earth and Moon. It describes the state-of-the-art in seismic tomography, with emphasis on the new findings obtained by applying tomographic methods in local, regional, and global scales for understanding the generating mechanism of large and great earthquakes such as the 2011 Tohoku-oki earthquake (Mw 9.0), crustal and upper mantle structure, origin of active arc volcanoes and intraplate volcanoes including hotspots, heterogeneous structure of subduction zones, fate of subducting slabs, origin of mantle plumes, mantle convection, and deep Earth dynamics. The first lunar tomography and its implications for the mechanism of deep moonquakes and lunar evolution are also introduced.

This thesis makes two important contributions to plasma physics. The first is the extension of the seminal theoretical works of Spitzer and Braginskii, which describe the basics of particle interactions in plasma, to relativistic systems. Relativistic plasmas have long been studied in high-energy astrophysics and are becoming increasingly attainable in the laboratory. The second is the design of a new class of photon-photon collider, which is the first capable of detecting the Breit-Wheeler process. Though it offers the simplest way for light to be converted into matter, the process has never been detected in the 80 years since its theoretical prediction. The experimental scheme proposed here exploits the radiation used in inertial confinement fusion experiments and could in principle be implemented in one of several current-generation facilities.

A complete solution for problems of vibration control in structures that may be subject to a broadband primary vibration field, this book addresses the following steps: experimental identification of the dynamic model of the structure; optimal placement of sensors and actuators; formulation of control constraints in terms of controller frequency response shape; controller design and simulation; and controller implementation and rapid prototyping. The identification procedure is a gray-box approach tailored to the estimation of modal parameters of large-scale flexible structures. The actuator/sensor placement algorithm maximizes a modal controllability index improving the effectiveness of the control. Considering limitations of sensors and actuators, the controller is chosen as a stable, band-pass MIMO system resulting from the closed-form solution of a robust control problem. Experimental results on an aeronautical stiffened skin panel are presented using rapid-prototyping hardware.

This outstanding thesis by Dominic Bowman provides a thorough investigation of long-standing questions as to whether amplitude modulation is astrophysical, whether it offers insights into pulsating stars, and whether simple beating of modes with stable amplitudes is unrecognised because of a lack of frequency resolution. In this thesis, the author studied a uniform sample of 983 delta Scuti stars-the most common type of main-sequence heat engine pulsator-that were observed nearly continuously for 4 years at stunning photometric precision of only a few parts per million by the Kepler space mission. With no mission planned to supersede the Kepler 4-year data set, this thesis will stand as the definitive study of these questions for many years. With revolutionary photometric data from the planet-hunting Kepler space mission, asteroseismic studies have been carried out on many hundreds of main-sequence solar-type stars and about 10,000 red giants. It is easy to understand why those stochastically driven stars have highly variable amplitudes. Over much of the rest of the Hertzsprung-Russell (HR) diagram, stellar pulsations are driven by heat mechanisms, which are much more regular than the stochastic driving in solar-like pulsators. Yet for decades, amplitude and frequency modulation of pulsation modes have been observed in almost all types of heat-driven pulsating stars. The author shows that the amplitude and frequency modulation are astrophysical, and he has investigated their implications and prospects to provide new insights into the delta Scuti stars and the many other types of heat-engine pulsators across the HR diagram.

This book makes good background reading for much of modern magnetospheric physics. Its origin was a Festspiel for Professor Jim Dungey, former professor in the Physics Department at Imperial College on the occasion of his 90th birthday, 30 January 2013. Remarkably, although he retired 30 years ago, his pioneering and, often, maverick work in the 50's through to the 70's on solar terrestrial physics is probably more widely appreciated today than when he retired. Dungey was a theoretical plasma physicist. The book covers how his reconnection model of the magnetosphere evolved to become the standard model of solar-terrestrial coupling. Dungey's open magnetosphere model now underpins a holistic picture explaining not only the magnetic and plasma structure of the magnetosphere, but also its dynamics which can be monitored in real time. The book also shows how modern day simulation of solar terrestrial coupling can reproduce the real time evolution of the solar terrestrial system in ways undreamt of in 1961 when Dungey's epoch-making paper was published. Further contributions on current Earth magnetosphere research and space plasma physics included in this book show how Dungey's basic ideas have remained explanative 50 years on. But the Festspiel also introduced some advances that possibly Dungey had not foreseen. One of the contributions presented in this book is on the variety of magnetospheres of the solar system which have been seen directly during the space age, discussing the variations in spatial scale and reconnection time scale and comparing them in respect of Earth, Mercury, the giant planets as well as Ganymede.