Materials science is the prime example of an interdisciplinary science. It - compasses the ?elds of physics, chemistry, material science, electrical en- neering, chemical engineering and other disciplines. Success has been o- standing. World-class accomplishments in materials have been recognized by NobelprizesinPhysicsandChemistryandgivenrisetoentirelynewtechno- gies. Materials science advances have underpinned the technology revolution that has driven societal changes for the last ?fty years. Obviouslytheendisnotinsight!Futuretechnology-basedproblemsd- inatethecurrentscene.Highonthelistarecontrolandconservationofenergy and environment, water purity and availability, and propagating the inf- mation revolution. All fall in the technology domain. In every case proposed solutions begin with new forms of materials, materials processing or new arti?cial material structures. Scientists seek new forms of photovoltaics with greater e?ciency and lower cost. Water purity may be solved through surface control, which promises new desalination processes at lower energy and lower cost. Revolutionary concepts to extend the information revolution reside in controlling the "spin" of electrons or enabling quantum states as in quantum computing. Ion-beam experts make substantial contributions to all of these burgeoning sciences.

With contributions by leading theoreticians, this book presents the discoveries of hitherto hidden connections between seemingly unrelated fields of fundamental physics. The topics range from cosmology and astrophysics to nuclear-, particle- and heavy-ion science. A current example concerns the sensitivity of gravitational wave spectra to the phase structure of dense nuclear and quark matter in binary neutron star collisions. The contributions by Hanauske and Stoecker as well as Banik and Bandyopadhyay relate the consequent insights to hot dense nuclear matter created in supernova explosions and in high-energy heavy-ion collisions. Studies of the equation of state for neutron stars are also presented, as are those for nuclear matter in high-energy heavy-ion collisions. Other reviews focus on QCD-thermodynamics, charmed mesons in the quark-gluon plasma, nuclear theory, extensions to the standard general theory of relativity, new experimental developments in heavy ion collisions and renewable energy networks. The book will appeal to advanced students and researchers seeking a broad view of current challenges in theoretical physics and their interconnections.

This book describes the fabrication of a frequency-based electronic tongue using a modified glassy carbon electrode (GCE), opening a new field of applying organic precursors to achieve nanostructure growth. It also presents a new approach to optimizing nanostructures by means of statistical analysis. The chemical vapor deposition (CVD) method was utilized to grow vertically aligned carbon nanotubes (CNTs) with various aspect ratios. To increase the graphitic ratio of synthesized CNTs, sequential experimental strategies based on response surface methodology were employed to investigate the crystallinity of CNTs. In the next step, glucose oxidase (GOx) was immobilized on the optimized multiwall carbon nanotubes/gelatin (MWCNTs/Gl) composite using the entrapment technique to achieve enzyme-catalyzed oxidation of glucose at anodic potentials, which was drop-casted onto the GCE. The modified GCE's performance indicates that a GOx/MWCNTs/Gl/GC electrode can be utilized as a glucose biosensor with a high direct electron transfer rate between GOx and MWCNTs/Gl. It was possible to use the fabricated biosensor as an electronic tongue thanks to a frequency-based circuit attached to the electrochemical cell. The results indicate that the modified GCE (with GOx/MWCNTs/Gl) holds promising potential for application in voltammetric electronic tongues.

Albert Einstein's General Theory of Relativity, published in 1915, made a remarkable prediction: gravitational radiation. Just like light (electromagnetic radiation), gravity could travel through space as a wave and affect any objects it encounters by alternately compressing and expanding them. However, there was a problem. The force of gravity is around a trillion, trillion, trillion times weaker than electromagnetism so the calculated compressions and expansions were incredibly small, even for gravity waves resulting from a catastrophic astrophysical event such as a supernova explosion in our own galaxy. Discouraged by this result, physicists and astronomers didn't even try to detect these tiny, tiny effects for over 50 years. Then, in the late 1960s and early 1970s, two events occurred which started the hunt for gravity waves in earnest. The first was a report of direct detection of gravity waves thousands of times stronger than even the most optimistic calculation. Though ultimately proved wrong, this result started scientists thinking about what instrumentation might be necessary to detect these waves. The second was an actual, though indirect, detection of gravitational radiation due to the effects it had on the period of rotation of two 'neutron stars' orbiting each other. In this case, the observations were in exact accord with predictions from Einstein's theory, which confirmed that a direct search might ultimately be successful. Nevertheless, it took another 40 years of development of successively more sensitive detectors before the first real direct effects were observed in 2015, 100 years after gravitational waves were first predicted. This is the story of that hunt, and the insight it is producing into an array of topics in modern science, from the creation of the chemical elements to insights into the properties of gravity itself.

"Advances in Imaging and Electron Physics" merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy." This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.
* Updated with contributions from leading international scholars and industry experts
* Discusses hot topic areas and presents current and future research trends
* Invaluable reference and guide for physicists, engineers and mathematicians

This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.

In this thesis single-molecule fluorescence resonance energy transfer (FRET) spectroscopy was used to study the folding of a protein that belongs to the large and important family of repeat proteins. Cohen shows that the dynamics of the expanded conformations is likely to be very fast, suggesting a spring-like motion of the whole chain. The findings shed new light on the elasticity of structure in repeat proteins, which is related to their function in binding multiple and disparate partners. This concise research summary provides useful insights for students beginning a PhD in this or a related area, and researchers entering this field.

This volume is a collection of articles from the ISSBMR 7th Course: Structure and Biophysics - New Technologies for Current Challenges in Biology and Beyond. This NATO Advanced Institute (ASI) was held at the Ettore Majorana Foundation and Centre for Scientific Culture in Sicily. The ASI brought together a diverse group of experts in the fields of Structural Biology, Biophysics and Physics. Prominent lecturers, from seven different countries, and students from around the world participated. The session addressed the treatment and detection of bioterrorism agents, and focused on critical partner country priorities in biotechnology, materials and drug discovery. The range of topics represents the diversity of critical problems between structural biology, biochemistry and biophysics, in which lies the fertile ground of drug development, biotechnology and new materials.

The fourth edition of SEG's best seller is a valuable, comprehensive reference that is a must for every geophysicist, geologist, explorationist, engineer, energy adviser, economist, editor, and student involved in the field. Hundreds of terms have been added since publication of the third edition in 1991, reflecting rapid evolution of the science, especially in the areas of engineering and production problems, 3D (including multicomponent) acquisition and processing, visualization, S- and converted waves, interpretation, anisotropy, AVO, geostatistics, geohazards, neural networks, tomography, downhole measurements, horizontal drilling, and deepwater work. Definitions of hundreds of other terms have been updated. The dictionary's title has been modified slightly to reflect growth in application of geophysical methods, with the word Applied replacing the word Exploration. The dictionary includes a guide to pronunciation and a list of reference figures and tables. A CD containing the dictionary in searchable PDF format also is included.

This book makes good background reading for much of modern magnetospheric physics. Its origin was a Festspiel for Professor Jim Dungey, former professor in the Physics Department at Imperial College on the occasion of his 90th birthday, 30 January 2013. Remarkably, although he retired 30 years ago, his pioneering and, often, maverick work in the 50's through to the 70's on solar terrestrial physics is probably more widely appreciated today than when he retired. Dungey was a theoretical plasma physicist. The book covers how his reconnection model of the magnetosphere evolved to become the standard model of solar-terrestrial coupling. Dungey's open magnetosphere model now underpins a holistic picture explaining not only the magnetic and plasma structure of the magnetosphere, but also its dynamics which can be monitored in real time. The book also shows how modern day simulation of solar terrestrial coupling can reproduce the real time evolution of the solar terrestrial system in ways undreamt of in 1961 when Dungey's epoch-making paper was published. Further contributions on current Earth magnetosphere research and space plasma physics included in this book show how Dungey's basic ideas have remained explanative 50 years on. But the Festspiel also introduced some advances that possibly Dungey had not foreseen. One of the contributions presented in this book is on the variety of magnetospheres of the solar system which have been seen directly during the space age, discussing the variations in spatial scale and reconnection time scale and comparing them in respect of Earth, Mercury, the giant planets as well as Ganymede.

This book presents timely work on the nature of the physical processes underpinning two of the basic characteristics of the gas structure in the innermost region of Active Galactic Nuclei (AGN): ionized outflows and emission line regions. In addition, it describes physics-based methods for estimating the density of the astrophysical plasma surrounding AGN. All numerical computations of the photoionized gas employ the most advanced codes available (CLOUDY and TITAN). Calculations of the radiative transfer are based on the assumption of thermal and ionization equilibrium. Promising preliminary examples of comparison with current observations are included for several individual AGN. All of them suggest that the absorbing/emitting gas should have a density on the order of 1012 cm-3. Future observations will provide more objects to verify these results, and will allow us to put constraints on the launch radius of ionized outflows and therefore on the mass loading and kinetic energy outflow rates. These rates, in turn, are crucial to estimating whether the outflows have a significant feedback impact on star formation and metal enrichment in the interstellar medium of the host galaxy. In closing, the book discusses a representative example of applying powerful photoionization techniques to explain the complex physics of the AGN environment.

This book on pressure-induced phase transitions in AB2X4 chalcogenide compounds deals with one important AmBnXp material. The interest in these materials is caused by their properties. The results are discussed for three main groups of structural families: cubic-spinel structures, defective tetragonal structures, and other structures like layered and wurtzite-type modifications. A systematic analysis of the behavior of cubic (spinel), tetragonal (defect chalcopyrites and stannites) and other crystal modifications of AB2X4 compounds under hydrostatic pressure is performed. The behavior of AIIAl2S4, AIIGa2S4, AIIAl2Se4 and AIIGa2Se4 compounds with defective tetragonal structures, compounds with layered and wurtzite structures under hydrostatic pressure and the pressure dependence of the band gap, lattice parameters, interatomic distances, vibrational modes and pressure-induced phase transitions is discussed. Many of these compounds, except oxide spinels, undergo a pressure-induced phase transition towards the rocksalt-type structure. The phase transition is preceded by disorder in the cation sublattice. The dependence of the transition pressure to the rocksalt-type structure as a function of the compound ionicity and the size criterion is analyzed. At high pressures, all ordered-vacancy compounds are found to exhibit a band anticrossing between several conduction bands that leads to a strong decrease of its pressure coefficient and consequently to a strong non-linear pressure dependence of the direct bandgap energy. Theoretical studies of phase transitions in several ordered-vacancy compounds reveal that the existence of ordered vacancies alter the cation-anion bond distances and their compressibilities. The book is written for students, Ph D. students and specialists in materials science, phase transitions and new materials.

This book summarizes the basic physics of graphite and newly discovered phenomena in this material. The book contains the knowledge needed to understand novel properties of functionalized graphite demonstrating the occurrence of remarkable phenomena in disordered graphite and graphite-based heterostructures. It also discusses applications of thin graphitic samples in future electronics. Graphite consists of a stack of nearly decoupled two-dimensional graphene planes. Because of the low dimensionality and the presence of Dirac fermions, much of graphite physics resembles that of graphene. On the other hand, the multi-layered nature of the graphite structure together with structural and/or chemical disorder are responsible for phenomena that are not observed yet in graphene, such as ferromagnetic order and superconductivity. Each chapter was written by one or more experts in the field whose contributions were relevant in the (re)discovery of (un)known phenomena in graphite. The book is intended as reference for beginners and experts in the field, introducing them to many aspects of the new physics of graphite, with a fresh overview of recently found phenomena and the theoretical frames to understand them.

This thesis sheds new light on the worldwide first electrical manipulation of a single nuclear spin. Over the last four decades, the size of a bit, the smallest logical unit in a computer, has decreased by more than two orders of magnitude and will soon reach a limit where quantum phenomena become important. Inspired by the power of quantum mechanics, researchers have already identified pure quantum systems, having, analog to a classical bit, two controllable and readable states. In this regard, the inherent spin of electrons or nuclei with its two eigenstates, spin up and spin down, is a promising candidate. Using expertise in the field of single-molecule magnets, the author developed a molecular transistor, which allows quantum information to be written onto a single nuclear spin by means of an electric field only, and, in addition, enables the electronic read-out of this quantum state. This novel approach opens a path to addressing and manipulating individual nuclear spins within a very confined space (a single molecule), at high speed. Thus, the author was able to show that single molecule magnets are promising candidates for quantum information processing, which is triggering a new field of research towards molecular quantum electronics.

The Workshop "Science with the VLT in the ELT Era" held in Garching from 8th to 12th October 2007 was organised by ESO, with support from its Scienti c and Technical Committee, to provide a forum for the astronomical community to debate the long term future of ESO's Very Large Telescope (VLT) and its interferometric mode (VLTI). In particular it was considered useful for future planning to evaluate how its science use may evolve over the next decade due to competition and/or synergy with new facilities such as ALMA, JWST and, hopefully, at least one next generation 30-40 m extremely large telescope whose acronym appears in the title to symbolise this wider context. These discussions were also held in the fresh light of the Science Vision recently developed within ASTRONET as the rst step towards a 20 year plan for implementing astronomical facilities-the rst such attempt within Europe. Speci c ideas and proposals for new, second generation VLT/I instruments were also solicited following a tradition set by several earlier Workshops held since the start of the VLT development. The programme consisted of invited talks and reviews and contributed talks and posters. Almost all those given are included here although, unfortunately not the several lively but constructive discussion sessions.

This book presents the forensic geoscience in general and, in particular, in Italy and their application to peculiar crimes. Italy is internationally relevant due to the presence of different kinds of "geo-crimes" (in the first place, environmental mafia), and is emblematic to understanding the best way to fight these crimes. This book will not only offer a new view point to comprehending these "geo-crimes", but also fresh and updated results of the different methods applied to fight against these crimes. This book is unique in that it is not a collection of articles but an individual work with the same theme beginning with a state-of-the-art of these disciplines to their international value passing through several case studies.

This book provides an introduction to the physics of interstellar gas in the Galaxy. It deals with the diffuse interstellar medium which supplies a complex environment for exploring the neutral gas content of a galaxy like the Milky Way and the techniques necessary for studying this non-stellar component. After an initial exposition of the phases of the interstellar medium and the role of gas in a spiral galaxy, the authors discuss the transition from atomic to molecular gas. They then consider basic radiative transfer and molecular spectroscopy with particular emphasis on the molecules useful for studying low-density molecular gas. Observational techniques for investigating the gas and the dust component of the diffuse interstellar medium throughout the electromagnetic spectrum are explored emphasizing results from the recent Herschel and Planck missions. A brief exposition on dust in the diffuse interstellar medium is followed by a discussion of molecular clouds in general and high-latitude molecular clouds in particular. Ways of calibrating CO observations with the molecular hydrogen content of a cloud are examined along with the dark molecular gas controversy. High-latitude molecular clouds are considered in detail as vehicles for applying the techniques developed in the book. Given the transient nature of diffuse and translucent molecular clouds, the role of turbulence in the origin and dynamics of these objects is examined in some detail. The book is targeted at graduate students or postdocs who are entering the field of interstellar medium studies.

The ability of storing, managing and giving access to the huge quantity of data collected by astronomical observatories is one of the major challenges of modern astronomy. At the same time, the growing complexity of data systems implies a change of concepts: the scientist has to manipulate data as well as information. Developments of the "World Wide Web" bring answers to these problems. The book presents a wide selection of databases, archives, data centres and information systems. Descriptions are included, together with their scientific context and motivations. This volume should prove a useful tool for astronomers, librarians, data specialists and computer engineers.

This book on multiscale seismic tomography, written by one of the leaders in the field, is suitable for undergraduate and graduate students, researchers, and professionals in Earth and planetary sciences who need to broaden their horizons about seismotectonics, volcanism, and interior structure and dynamics of the Earth and Moon. It describes the state-of-the-art in seismic tomography, with emphasis on the new findings obtained by applying tomographic methods in local, regional, and global scales for understanding the generating mechanism of large and great earthquakes such as the 2011 Tohoku-oki earthquake (Mw 9.0), crustal and upper mantle structure, origin of active arc volcanoes and intraplate volcanoes including hotspots, heterogeneous structure of subduction zones, fate of subducting slabs, origin of mantle plumes, mantle convection, and deep Earth dynamics. The first lunar tomography and its implications for the mechanism of deep moonquakes and lunar evolution are also introduced.

This book concisely expounds the fundamental concepts, phenomena, theories and procedures in a complete and systematic sense. In this book, not only almost all the important achievements from predecessors but also the contributions from the author himself have been summed up profoundly. Starting from the derivation of fundamental equations, various classical acoustical phenomena such as reflection, refraction, scattering diffraction and absorption in atmosphere, as well as the influences of gravitation and rotation of the earth on the behaviors of different atmospheric waves including acoustic waves, have been discussed in viewpoints of wave acoustics and geometrical acoustics respectively. The recent developments of several computation methods in the field of atmospheric acoustics have been introduced in some detail. As for the application aspects, atmospheric remote sensing has been discussed from the angle of inverse problems.

This thesis makes two important contributions to plasma physics. The first is the extension of the seminal theoretical works of Spitzer and Braginskii, which describe the basics of particle interactions in plasma, to relativistic systems. Relativistic plasmas have long been studied in high-energy astrophysics and are becoming increasingly attainable in the laboratory. The second is the design of a new class of photon-photon collider, which is the first capable of detecting the Breit-Wheeler process. Though it offers the simplest way for light to be converted into matter, the process has never been detected in the 80 years since its theoretical prediction. The experimental scheme proposed here exploits the radiation used in inertial confinement fusion experiments and could in principle be implemented in one of several current-generation facilities.

Sound waves are the only practical means of remote investigation of the sea and its bottom and transmission in seawater. Underwater acoustics has become one of the major technologies used in the exploration and exploitation of the oceans for scientific, industrial, or military/naval purposes. It is widely employed in the fields of ocean engineering, seafloor mapping, defence, oceanography, navigation, and fisheries.

Dr Xavier Lurton is a renowned specialist in underwater acoustics. He has worked in this field as a scientist, engineer, project manager and teacher since 1981 and has participated in many scientific projects, systems developments and at-sea cruises. In the second edition of his book, Dr Lurton provides an updated and extended introduction to underwater acoustics, including coverage of the physical processes and their basic modeling, different underwater acoustic systems and their practical applications and a description and assessment of the various technologies. Dr Lurton has extensive experience as a lecturer in undergraduate and postgraduate schools, including naval academies. This book is based on his direct, first-hand experience of the many aspects of underwater acoustics in seas around the world, at the forefront of current research and development efforts.

Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities.
Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.
The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.
* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.
* Guides the reader from basic principles and methods to cutting edge applications.
* There is NO comparable book on the market to fill this fast growing field.

Nanoneuroscience is the study of computationally relevant biomolecules found inside neurons. Because of recent technological advances at the nanometer scale, scientists have at their disposal increasingly better ways to study the brain and the biophysics of its molecules. This book describes how biomolecules contribute to the operations of synapses and perform other computationally relevant functions inside dendrites. These biomolecular operations considerably expand the brain-computer analogy - endowing each neuron with the processing power of a silicon-based multiprocessor. Amazingly, the brain contains hundreds of billions of neurons.