Lightning represents a natural phenomenon of substantial interest. Due to its complex nature, research continues in many countries and reveals amazing results. Lightning is actively observed because of its relevance to Earth climate and air composition in addition to the classical aspects of related human fatalities and damage to forests, buildings, power lines, aircraft, structures and electronic devices. In this volume, the most important contemporary questions on lightning are addressed and analyzed under many experimental and theoretical aspects. Lightning detection techniques using ground-based and space-borne methods are described, along with network engineering and statistical analysis. Contributions detail research on atmospheric electricity, cloud physics, lightning physics, modeling of electrical storms and middle atmospheric events. Special phenomena such as triggered lightning and sprite observations are examined. Lightning-induced nitrogen oxides and their effects on atmospheric chemistry and climate are discussed. Each topic is presented by international experts in the field. Topics include: * air chemistry * convective storms * infrasound from lightning * lightning and climate change * lightning and precipitation * lightning and radiation * lightning and supercells * lightning and thunderstorms * lightning detection * lightning from space * lighting protection * lightning return strokes * observations and interpretations * spatial distribution and frequency * triggered lightning * weather extremes

This short monograph presents the theory of electromagnetic pulses in a simple and physical way. All pulses discussed are exact solutions of the Maxwell equations, and have finite energy, momentum and angular momentum. There are five chapters: on Fundamentals, Solutions of the Wave Equation, Electromagnetic Pulses, Angular Momentum, and Lorentz Transformations. Nine Appendices cover mathematical or associated aspects, such as chiral measures of electromagnetic fields. The subject matter is restricted to free-space classical electrodynamics, but contact is made with quantum theory in proofs that causal pulses are equivalent to superpositions of photons.

This book focuses on the application of fluorescence to study motor proteins (myosins, kinesins, DNA helicases and RNA polymerases). It is intended for a large community of biochemists, biophysicists and cell biologists who study a diverse collection of motor proteins. It can be used by researchers to gain an insight into their first experiments, or by experienced researchers who are looking to expand their research to new areas. Each chapter provides valuable advice for executing the experiments, along with detailed background knowledge in order to develop own experiments.

Mars, the most habitable of our sister planets, holds a special place in our imaginations and in our space exploration program. Fully half of NASA's planetary exploration effort is now devoted to Mars. Key questions include: Has Mars ever harbored life? Is there life on Mars now? Will humans be able to survive on the Martian surface? Answers to these questions lie in determining the present location of water on Mars and its likely inventory in the past, and in determining the present radiation environment of Mars. The 2001 Mars Odyssey Mission contributes greatly these answers by detecting near-surface water through measurements of neutron flux, from the detection of carbonates, and the quantification of its radiation environment. This book captures the objectives, the design of the mission and the details of the instruments carried to Mars. It should be of interest to every scientist interested in participating in the on-going exploration of Mars from graduate students to senior scientists as it provides the background information essential to interpret the many exciting results now appearing from the mission.

This is the first book that is not exclusively focused on ion channels functioning in sensory mechanisms that are characteristic of animals and humans, but also describes the role of ion channels in signal transduction mechanisms found in microbial cells and plants. It summarizes comprehensively the progress that has been made in studies of ion channels and their role in sensory physiology.

The book provides an elaborate treatment of groundwater prospecting and management covering remote sensing, geological-geophysical cum hydrogeological studies, exploration (geological and geophysical), development (well logging techniques, pump test, its analysis and applications in well design), contamination (pollution of groundwater) and regulatory legislations regarding groundwater utilization under one cover. The book presents an elucidation of fundamental and theoretical background of each technique supported by necessary illustrative examples and exclusive case studies. It is a text-cum-reference book not only for students, research scholars and practicing earth scientists but also for practicing civil and agricultural engineers working in the application of groundwater resources, engaged in its exploration, development, contamination, legislation and management. The general readers can also refer the book for understanding the groundwater domain for adequate knowledge, as groundwater resources are essential life support commodity which is replenishable but not inexhaustible.

This book provides an introduction to the mathematical aspects of Euler's elastic theory and its application. The approach is rigorous, as well as visually depicted, and can be easily digested. The first few chapters introduce the needed mathematical concepts from geometry and variational calculus. The formal definitions and proofs are always illustrated through complete derivations and concrete examples. In this way, the reader becomes acquainted with Cassinian ovals, Sturmian spirals, co-Lemniscates, the nodary and the undulary, Delaunay surfaces, and their generalizations. The remaining chapters discuss the modeling of membranes, mylar balloons, rotating liquid drops, Hele-Shaw cells, nerve fibers, Cole's experiments, and membrane fusion. The book is geared towards applied mathematicians, physicists and engineers interested in Elastica Theory and its applications.

The critically acclaimed serialized review journal for nearly fifty years, Advances in Geophysics is a highly respected publication in the field of geophysics. Since 1952, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 45 volumes, the Serial contains much material still relevant today-truly an essential publication for researchers in all fields of geophysics.

Neuroscience is an interdisciplinary field that strives to understand the functioning of neural systems at levels ranging from biomolecules and cells to behaviour and higher brain functions (perception, memory, cognition). Neurophysics has flourished over the past three decades, becoming an indelible part of neuroscience, and has arguably entered its maturity. It encompasses a vast array of approaches stemming from theoretical physics, computer science, and applied mathematics. This book provides a detailed review of this field from basic concepts to its most recent development.

GPS and GNSS Technology in Geosciences offers an interdisciplinary approach to applying advances in GPS/GNSS technology for geoscience research and practice. As GPS/GNSS signals can be used to provide useful information about the Earth's surface characteristics and land surface composition, GPS equipment and services for commercial purposes continues to grow, thus resulting in new expectations and demands. This book provides case studies for a deeper understanding of the operation and principles of widely applied approaches and the benefits of the technology in everyday research and activities.

This work establishes linear-scaling density-functional theory (DFT) as a powerful tool for understanding enzyme catalysis, one that can complement quantum mechanics/molecular mechanics (QM/MM) and molecular dynamics simulations. The thesis reviews benchmark studies demonstrating techniques capable of simulating entire enzymes at the ab initio quantum-mechanical level of accuracy. DFT has transformed the physical sciences by allowing researchers to perform parameter-free quantum-mechanical calculations to predict a broad range of physical and chemical properties of materials. In principle, similar methods could be applied to biological problems. However, even the simplest biological systems contain many thousands of atoms and are characterized by extremely complex configuration spaces associated with a vast number of degrees of freedom. The development of linear-scaling density-functional codes makes biological molecules accessible to quantum-mechanical calculation, but has yet to resolve the complexity of the phase space. Furthermore, these calculations on systems containing up to 2,000 atoms can capture contributions to the energy that are not accounted for in QM/MM methods (for which the Nobel prize in Chemistry was awarded in 2013) and the results presented here reveal profound shortcomings in said methods.

This exhaustive work sheds new light on unsolved questions in gamma-ray astrophysics. It presents not only a complete introduction to the non-thermal Universe, but also a description of the Imaging Atmospheric Cherenkov technique and the MAGIC telescopes. The Fermi-LAT satellite and the HAWC Observatory are also described, as results from both are included. The physics section of the book is divided into microquasars and pulsar wind nebulae (PWNe), and includes extended overviews of both. In turn, the book discusses constraints on particle acceleration and gamma-ray production in microquasar jets, based on the analyses of MAGIC data on Cygnus X-1, Cygnus X-3 and V404 Cygni. Moreover, it presents the discovery of high-energy gamma-ray emissions from Cygnus X-1, using Fermi-LAT data. The book includes the first joint work between MAGIC, Fermi-LAT and HAWC, and discusses the hypothetical PWN nature of the targets in depth. It reports on a PWN population study that discusses, for the first time, the importance of the surrounding medium for gamma-ray production, and in closing presents technical work on the first Large-Size-Telescope (LST; CTA Collaboration), along with a complete description of the camera.

One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in: (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying and optimizing the tissue engineering process, e.g. by adapting bioreactor design to improve quality and quantity of the final product; and (iii) assessing the influence of the in vivo environment on the behavior of the tissue engineering product, e.g. by investigating vascular ingrowth. The book presents examples of each of the above mentioned areas of computational modeling. The underlying tissue engineering applications will vary from blood vessels over trachea to cartilage and bone. For the chapters describing examples of the first two areas, the main focus is on (the optimization of) mechanical signals, mass transport and fluid flow encountered by the cells in scaffolds and bioreactors as well as on the optimization of the cell population itself. In the chapters describing modeling contributions in the third area, the focus will shift towards the biology, the complex interactions between biology and the micro-environmental signals and the ways in which modeling might be able to assist in investigating and mastering this complexity. The chapters cover issues related to (multiscale/multiphysics) model building, training and validation, but also discuss recent advances in scientific computing techniques that are needed to implement these models as well as new tools that can be used to experimentally validate the computational results.

Mathematically, natural disasters of all types are characterized by heavy tailed distributions. The analysis of such distributions with common methods, such as averages and dispersions, can therefore lead to erroneous conclusions. The statistical methods described in this book avoid such pitfalls. Seismic disasters are studied, primarily thanks to the availability of an ample statistical database. New approaches are presented to seismic risk estimation and forecasting the damage caused by earthquakes, ranging from typical, moderate events to very rare, extreme disasters. Analysis of these latter events is based on the limit theorems of probability and the duality of the generalized Pareto distribution and generalized extreme value distribution. It is shown that the parameter most widely used to estimate seismic risk - Mmax, the maximum possible earthquake value - is potentially non-robust. Robust analogues of this parameter are suggested and calculated for some seismic catalogues. Trends in the costs inferred by damage from natural disasters as related to changing social and economic situations are examined for different regions.

The results obtained argue for sustainable development, whereas entirely different, incorrect conclusions can be drawn if the specific properties of the heavy-tailed distribution and change in completeness of data on natural hazards are neglected.

This pioneering work is directed at risk assessment specialists in general, seismologists, administrators and all those interested in natural disasters and their impact on society.

This book is the latest volume in a highly successful series within Comprehensive Biochemistry and provides a historical and autobiographical perspective of the development of the field through the contributions of leading individuals who reflect on their careers and their impact on biochemistry. The book is essential reading for everybody, from graduate student to professor, placing in context major advances not only in biochemical terms but in relation to historical and social developments. Readers will be delighted by the lively style and the insight into the lives and careers of leading scientists of their time.

Unlike most natural colours that are based on pigment absorption, the striking iridescent and intense colouration of many butterflies, birds or beetles stems from the interaction of light with periodic sub-micrometer surface or volume patterns, so called "photonic structures". These "structural colours" are increasingly well understood, but they are difficult to create artificially and exploit technologically. In this thesis the field of natural structural colours and biomimetic photonic structures is covered in a wide scope, ranging from plant photonics to theoretical optics. It demonstrates diffractive elements on the petal surfaces of many flowering plant species; these form the basis for the study of the role of structural colours in pollinator attraction. Self-assembly techniques, combined with scale able nanofabrication methods, were used to create complex artificial photonic structures inspired by those found in nature. In particular, the colour effect of a Papilio butterfly was mimicked and, by variation of its design motive, enhanced. All photonic effects described here are underpinned by state-of-the-art model calculations.

Physical Oceanography of the Dying Aral Sea describes the background, present crisis state, and possible future of this peculiar inland water body from the physical oceanographic standpoint. Based on a wide range of material, a large part of which was published in Russian and has not been previously available to the international reader, the book first provides an historical overview of this unique system, which possesses both lake and sea properties.

Next, the current physical state of the lake is described, partly based on original field research and model experiments, along with the remote sensing data, model results and analyses extracted from recent literature. Next, book attempts to forecast the forthcoming state of the Aral Sea and identify plausible future scenarios. Finally, the book discusses the Aral Sea dessication viewd as a part of the global perspective.

While structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. This volume provides an introduction into techniques to assess structure and folding of RNA. Each chapter explains the theoretical background of one technique, and illustrates possibilities and limitations in selected application examples.

This book focuses on essential theories, methods and techniques in the field of environmental and engineering geophysics that can contribute to resource detection and environmental protection. Geophysics has been playing an important role in exploring the earth, locating vital resources and promoting the development of society. This book covers a range of topics including the exploration of modern resources, such as ore deposits, coal mines, shale gas and geothermal power, and the monitoring of geological disasters, including the rock-soil body, ground deformation, mines, specific rock-soil engineering disasters, desertification of land and environmental abnormalities. This book not only offers a valuable resource for geophysical researchers; it also demonstrates how geophysics theories and methods can be practically implemented to protect our environment and promote the development of human society.

This book elaborates on the acceleration of charged particles with ultrafast terahertz electromagnetic radiation. It paves the way for new, and improves many aspects of current, accelerator applications. These include providing shorter electron bunches for ultrafast time-resolved pump-probe spectroscopy, enabling complex longitudinal profiles to be imparted onto charged particle bunches and significantly improving the ability to synchronise an accelerator to an external laser. The author has developed new sources of terahertz radiation with attractive properties for accelerator-based applications. These include a radially biased large-area photoconductive antenna (PCA) that provided the largest longitudinally polarised terahertz electric field component ever measured from a PCA. This radially biased PCA was used in conjunction with an energy recovery linear accelerator for electron acceleration experiments at the Daresbury Laboratory. To achieve even higher longitudinally polarised terahertz electric field strengths, and to be able to temporally tune the terahertz radiation, the author investigated generation within non-linear optical crystals. He developed a novel generation scheme employing a matched pair of polarity inverted magnesium-oxide doped stoichiometric lithium niobate crystals, which made it possible to generate longitudinally polarised single-cycle terahertz radiation with an electric field amplitude an order of magnitude larger than existing sources.

Impact cratering is an important geological process on all solid planetary bodies, and, in the case of Earth, may have had major climatic and biological effects. Most terrestrial impact craters have been erased or modified beyond recognition. However, major impacts throw ejecta over large areas of the Earth's surface. Recognition of these impact ejecta layers can help fill in the gaps in the terrestrial cratering record and at the same time provide direct correlation between major impacts and other geological events, such as climatic changes and mass extinctions. This book provides the first summary of known distal impact ejecta layers