This book presents the latest research findings and reviews in the field of medical imaging technology, covering ultrasound diagnostics approaches for detecting osteoarthritis, breast carcinoma and cardiovascular conditions, image guided biopsy and segmentation techniques for detecting lung cancer, image fusion, and simulating fluid flows for cardiovascular applications. It offers a useful guide for students, lecturers and professional researchers in the fields of biomedical engineering and image processing.

This second edition of the book on Store-operated Ca2+ Entry Pathways has been updated with the newest discoveries that emerged in the field within the last five years. The crystal structure of the Ca2+ signaling core complex is described which adds to a new understanding of the molecular interactions involved. Each chapter has been revised and extended. The book retains its interdisciplinary approach and supplies biochemists, cell biologists and biophysicists as well as clinicians in immunology, neurology and cardiology with valuable information on Ca2+ signaling mechanisms, functions, dysfunctions and their consequences.

The conversion of energy generated in the Sun's interior creates its hot corona and a wealth of dynamical phenomena such as flares and mass ejections. Based on recent significant progress in understanding magnetic reconnection and a wealth of new observations of energetic particle signatures from the Sun, the present volume reviews the current theoretical and experimental status in the field. Paying attention to both the details and the broader picture, this book addresses both the experienced researcher as well as nonspecialist researchers from related areas and postgraduate students in astrophsics.

This course-tested textbook conveys the fundamentals of magnetic fields and relativistic plasma in diffuse cosmic media, with a primary focus on phenomena that have been observed at different wavelengths. Theoretical concepts are addressed wherever necessary, with derivations presented in sufficient detail to be generally accessible. In the first few chapters the authors present an introduction to various astrophysical phenomena related to cosmic magnetism, with scales ranging from molecular clouds in star-forming regions and supernova remnants in the Milky Way, to clusters of galaxies. Later chapters address the role of magnetic fields in the evolution of the interstellar medium, galaxies and galaxy clusters. The book is intended for advanced undergraduate and postgraduate students in astronomy and physics and will serve as an entry point for those starting their first research projects in the field.

The International Symposium on Biological Effects of Magnetic and Electrom- netic Fields was held from September 3-4, 1993 at Kyushu University in Fukuoka . Japan . Originally, it was only intended to be an informal gathering of many scientists who had accepted my invitation to visit Kyushu University after the XXIVth General Assembly of the International Union of Radio Science (URSI), held in Kyoto prior to our symposium . However, since so many distinguished scientists were able to come, it was decided that a more formal symposium would be possible . It was a very productive symposium and, as a result, many of the guests consented that it would be a good idea to gather all the information put forth at the meeting and have it published. In addition, although they were unfortunately unable to attend the symposium . many other distinguished scientists had also expressed their wish to contribute to this effort and, in so doing. help to increase understanding in this, as yet, relatively immature field of science . The question of both positive and negative effects of magnetic and electromagnetic fields on biological systems has become more and more important in our world today as they .

Cosmogenic radionuclides are radioactive isotopes which are produced by natural processes and distributed within the Earth system. With a holistic view of the environment the authors show in this book how cosmogenic radionuclides can be used to trace and to reconstruct the history of a large variety of processes. They discuss the way in which cosmogenic radionuclides can assist in the quantification of complex processes in the present-day environment. The book aims to demonstrate to the reader the strength of analytic tools based on cosmogenic radionuclides, their contribution to almost any field of modern science, and how these tools may assist in the solution of many present and future problems that we face here on Earth. The book provides a comprehensive discussion of the basic principles behind the applications of cosmogenic (and other) radionuclides as environmental tracers and dating tools. The second section of the book discusses in some detail the production of radionuclides by cosmic radiation, their transport and distribution in the atmosphere and the hydrosphere, their storage in natural archives, and how they are measured. The third section of the book presents a number of examples selected to illustrate typical tracer and dating applications in a number of different spheres (atmosphere, hydrosphere, geosphere, biosphere, solar physics and astronomy). At the same time the authors have outlined the limitations of the use of cosmogenic radionuclides. Written on a level understandable by graduate students without specialist skills in physics or mathematics, the book addresses a wide audience, ranging from archaeology, biophysics, and geophysics, to atmospheric physics, hydrology, astrophysics and space science.

This textbook presents in a unified manner the fundamentals of both continuous and discrete versions of the Fourier and Laplace transforms. These transforms play an important role in the analysis of all kinds of physical phenomena. As a link between the various applications of these transforms the authors use the theory of signals and systems, as well as the theory of ordinary and partial differential equations. The book is divided into four major parts: periodic functions and Fourier series, non-periodic functions and the Fourier integral, switched-on signals and the Laplace transform, and finally the discrete versions of these transforms, in particular the Discrete Fourier Transform together with its fast implementation, and the z-transform. This textbook is designed for self-study. It includes many worked examples, together with more than 120 exercises, and will be of great value to undergraduates and graduate students in applied mathematics, electrical engineering, physics and computer science.

Dynamic Biological Organization is a fascinating account of the living organisms as dynamic systems, based on the concept that the spatio-temporal coherence of events within a living system result from the intrinsic dynamics of the processes taking place within that sysem. The authors of this important work, Miguel Aon and Sonia Cortassa have travelled widely to work in some of the leading research laboratories to accumulate a large information base on which to assemble this book. Taking a transdisciplinary approach, the authors draw on work at the interface of biochemistry, genetics, physiology, thermodynamics, kinetics and biomathematics, using mathematical models throughout to corroborate and analyze the biological complexity presented. Emphasizing biological processes occuring at the cellular level. Dynamic Biological Organization gives exciting insights into the experimental and theoretical applications of modern scientific paradigms to fundamental biological processes.

Metaphors, generalizations and unifications are natural and desirable ingredients of the evolution of scientific theories and concepts. Physics, in particular, obviously walks along these paths since its very beginning. This book focuses on nonextensive statistical mechanics, a current generalization of Boltzmann-Gibbs (BG) statistical mechanics, one of the greatest monuments of contemporary physics. Conceived more than 130 years ago by Maxwell, Boltzmann and Gibbs, the BG theory exhibits uncountable - some of them impressive - successes in physics, chemistry, mathematics, and computational sciences, to name a few. Presently, more than two thousand publications, by over 1800 scientists around the world, have been dedicated to the nonextensive generalization. Remarkable applications have emerged, and its mathematical grounding is by now relatively well established. A pedagogical introduction to its concepts - nonlinear dynamics, extensivity of the nonadditive entropy, global correlations, generalization of the standard CLT's, among others - is presented in this book as well as a selection of paradigmatic applications in various sciences together with diversified experimental verifications of some of its predictions.

• This is the first pedagogical book on the subject, written by the proponent of the theory
• Presents many applications to interdisciplinary complex phenomena in virtually all sciences, ranging from physics to medicine, from economics to biology, through signal and image processing and others
• Offers a detailed derivation of results, illustrations and for the first time detailed presentation of Nonextensive Statistical Mechanics

Weights and measures form an essential part of our ingrained view of the world. It is just about impossible to function effectively without some internalized system of measurement.

The 157th IAU Symposium "The Cosmic Dynamo" was entirely dedicated to dynamo processes, which are fundamental to all cosmic scales. Dynamo theory concerns one of the few truly key questions of recent cosmic physics. A complicated interplay of rotation, magnetism and turbulence determines stellar and galactic activity for almost all the short and medium time scales. Behind these multiform phenomena, the cosmic dynamo works in various guises, all involving inductive and dissipative equilibria in rotating turbulent cosmic plasmas. This book presents an up-to-date survey on investigations and results of dynamo theory and related observations. It is intended for graduate scientists working in the field of cosmical magnetism and its related problems, especially convection, turbulence and, more generally, nonlinear physics.

In view of the current and forthcoming observational data on pulsar wind nebulae, this book offers an assessment of the theoretical state of the art of modelling them. The expert authors also review the observational status of the field and provide an outlook for future developments. During the last few years, significant progress on the study of pulsar wind nebulae (PWNe) has been attained both from a theoretical and an observational perspective, perhaps focusing on the closest, more energetic, and best studied nebula: the Crab, which appears in the cover. Now, the number of TeV detected PWNe is similar to the number of characterized nebulae observed at other frequencies over decades of observations. And in just a few years, the Cherenkov Telescope Array will increase this number to several hundreds, actually providing an essentially complete account of TeV emitting PWNe in the Galaxy. At the other end of the multi-frequency spectrum, the SKA and its pathfinder instruments, will reveal thousands of new pulsars, and map in exquisite detail the radiation surrounding them for several hundreds of nebulae. By carefully reviewing the state of the art in pulsar nebula research this book prepares scientists and PhD students for future work and progress in the field.

Want to know not just what makes rockets go up but how to do it optimally? Optimal control theory has become such an important field in aerospace engineering that no graduate student or practicing engineer can afford to be without a working knowledge of it. This is the first book that begins from scratch to teach the reader the basic principles of the calculus of variations, develop the necessary conditions step-by-step, and introduce the elementary computational techniques of optimal control. This book, with problems and an online solution manual, provides the graduate-level reader with enough introductory knowledge so that he or she can not only read the literature and study the next level textbook but can also apply the theory to find optimal solutions in practice. No more is needed than the usual background of an undergraduate engineering, science, or mathematics program: namely calculus, differential equations, and numerical integration. Although finding optimal solutions for these problems is a complex process involving the calculus of variations, the authors carefully lay out step-by-step the most important theorems and concepts. Numerous examples are worked to demonstrate how to apply the theories to everything from classical problems (e.g., crossing a river in minimum time) to engineering problems (e.g., minimum-fuel launch of a satellite). Throughout the book use is made of the time-optimal launch of a satellite into orbit as an important case study with detailed analysis of two examples: launch from the Moon and launch from Earth. For launching into the field of optimal solutions, look no further!

Many text books have been written on the subject "Exploration Geophysics." The majority of these texts focus on the theory and the mathematical treatment of the subject matter but lack treatment of practical aspects of geophysical exploration. This text is written in simple English to explain the physical meaning of jargon, or terms used in the industry. It describes how seismic data is acquired in 2-D and 3-D, how they are processed to convert the raw data to seismic vertical and horizontal cross sections, that are geologically meaningful, and how these and other data are interpreted to delineate a prospect. Workshops are included after each chapter and are designed to reinforce learning of the concepts presented.

Key Features:

Written in simple easy to understand language

Heavily illustrated to aid in understanding the text

End of chapter "Key words and workshop"

The text includes several appendices and answers for the selected workshop problems

Adaptive optics allows the theoretical limit of angular resolution to be achieved from a large telescope, despite the presence of turbulence. Thus an eight meter class telescope, such as one of the four in the Very Large Telescope operated by ESO in Chile, will in future be routinely capable of an angular resolution of almost 0.01 arcsec, compared tot he present resolution of about 0.5 arcsec for conventional imaging in good condition. All the world's major telescopes either have adaptive optics or are in the process of building AO systems. It turns out that a reasonable fraction of the sky can be observed using adaptive optics, with moderately good imaging quality, provided imaging in done in the near IR. To move out of the near IR, with its relatively poor angular resolution, astronomers need a laser guide star. There is a layer of Na atoms at approximately 90 km altitude that can be excited by a laser to produce such a source, or Rayleigh scattering can be employed lower in the atmosphere. But the production and use of laser guide stars is not trivial, and the key issues determining their successful implementation are discussed here, including the physics of the Na atom, the cone effect, tilt determination, sky coverage, and numerous potential astronomical applications.

What data is needed to complete a quantitative risk assessment for environmental and public health? How accurate does a quantitative risk assessment have to be? How confident does a risk assessor need to be when presenting risk estimates to a decision maker? Find out the answers to these questions and more with Comparative Environmental Risk Assessment, the first major commercial publication that describes the current state of the art in comparative environmental risk assessment. This book examines the problems involved in such analyses and offers ideas and thoughts for future development. The book examines major problems in this area and covers all aspects of the environment, including human and ecological health. Comparative Environmental Risk Assessment is an excellent guide for risk assessment experts, environmentalists, regulators, planners, legislators, scientists in industry, instructors, and students.

This book gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase. It provides organic chemists, biophysicists, and pharmacologists with an introduction to new techniques they can use to find the answers to yet unsolved questions. Laboratory sciences have bloomed with a variety of techniques to decipher the properties of the molecules of life. This volume introduces techniques used to investigate the properties of nucleic acids in the absence of solvent. It highlights the specificities pertaining to the studies of nucleic acids, although some of the techniques can similarly be applied to the study of other biomolecules, like proteins. The first part of the book introduces the techniques, from the transfer of nucleic acids to the gas-phase, to their detailed physico-chemical investigation. Each chapter is devoted to a specific molecular property, and illustrates how various approaches (experimental and theoretical) can be combined for the interpretation.
The second part of the book is devoted to applying the gas-phase approaches to solve specific questions related to the biophysics, biochemistry or pharmacology of nucleic acids.

The original work presented in this thesis constitutes an important contribution to modern Cosmic Ray (CR) physics, and comes during one of the most exciting periods of this field. The first part introduces a new numerical code (DRAGON) to model the CR propagation in our Galaxy. The code is then used to perform a combined analysis of CR data, making it possible to determine their propagation properties with unprecedented accuracy. The second part is dedicated to a theoretical interpretation of the recent crucial experimental results on cosmic electron and positron spectra (PAMELA, Fermi-LAT experiments). Using the tools developed in the first part of the thesis, the author convincingly argues for the existence of a new spectral component, which could arise either from local astrophysical sources, such as pulsars, or from Dark Matter annihilation or decay. This thesis is a highly advanced work; the methods, analysis and results are clearly and carefully presented. This work is set to become an important reference document for any future work in this area.

This volume is a review on coherent states and some of their applications. The usefulness of the concept of coherent states is illustrated by considering specific examples from the fields of physics and mathematical physics. Particular emphasis is given to a general historical introduction, general continuous representations, generalized coherent states, classical and quantum correspondence, path integrals and canonical formalism. Applications are considered in quantum mechanics, optics, quantum chemistry, atomic physics, statistical physics, nuclear physics, particle physics and cosmology. A selection of original papers is reprinted.

Market: Researchers in solid earth geophysics and planetary geophysics. This book is a record of the one-day symposium organized by the Space Policy Institute of the George Washington University's Elliot School of International Affairs, in cooperation with NASA's Office of Mission to Planet Earth. The meeting provided an authoritative overview of the progress that had been made to date in the study of Earth from space and identified the steps being taken to ensure that future space-based Earth observation missions make as great a scientific contribution as possible in support of the Earth system science concept.

These proceedings present selected research papers from CSNC 2018, held during 23rd-25th May in Harbin, China. The theme of CSNC 2018 is Location, Time of Augmentation. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC 2018, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.

It is only since recent years that the importance of the effects of outdoor lighting on the night-time environment and on the physical and mental health of humans is recognized on a wider scale. The related issue of light pollution is a particularly complex one, with potential conflicts of interest between the utilities, environmentalists, astronomers, the lighting industry and various government departments. Energy politics are always a sensitive issue, and light pollution is no exception to this rule.

The effects of light pollution on flora, fauna -including humans and their widely varying night-time activities- are often subtle and need extensive field studies to be quantified in a sensible manner.

The present conference, initiated by Commission 50 of the International Astronomical Union, is an attempt to bring together the astronomical community, the lighting industry, end-users, the utilities, and public authorities for a discussion and an exchange of ideas and information that will create goodwill among these groups and will thus contribute to making the global efforts to reduce pollution more efficient and effective.

Radio frequency pollution was also discussed in the context of radio astronomy and its efforts to create radio-quiet zones in collaboration with the government authorities that allocate frequency bands to the various users -mainly the telecommunications industry- and to protect the major planned and present radio observatories of the world.
The 3-day conference was attended by more than 130 representatives from 12 countries of all the above-mentioned groups, and a wide range of topics was discussed.

Some of the highlights were:
The presentationof the 1st world atlas of artificial night sky brightness (Cinzano et al.); the article by the International Darksky Association on their world-wide efforts to curb light pollution (Alvarez del Castillo et al.); the laws controlling light pollution implemented in Spain (Diaz et al.) and Chile (Sanhueza et al.), an overview of the work on radio frequency protection of sites (Cohen et al.) and the excellent introduction to the topic from the Chilean point of view (Daud).

Related topics in the book are light pollution education, aircraft contrails, space advertising (with an added document provided by the relevant UN commission), and an experiment on involving the population of an entire country in measuring sky brightness, by using the internet and the media.

The text is aimed at professionals from a wide range of disciplines related to lighting and its effects on the night-time environment in the broadest sense of the word. Lay persons interested in this emerging multi-disciplinary field can also find much of interest in this book.

Our contemporary understanding of brain function is deeply rooted in the ideas of the nonlinear dynamics of distributed networks. Cognition and motor coordination seem to arise from the interactions of local neuronal networks, which themselves are connected in large scales across the entire brain. The spatial architectures between various scales inevitably influence the dynamics of the brain and thereby its function. But how can we integrate brain connectivity amongst these structural and functional domains? Our Handbook provides an account of the current knowledge on the measurement, analysis and theory of the anatomical and functional connectivity of the brain. All contributors are leading experts in various fields concerning structural and functional brain connectivity. In the first part of the Handbook, the chapters focus on an introduction and discussion of the principles underlying connected neural systems. The second part introduces the currently available non-invasive technologies for measuring structural and functional connectivity in the brain. Part three provides an overview of the analysis techniques currently available and highlights new developments. Part four introduces the application and translation of the concepts of brain connectivity to behavior, cognition and the clinical domain. Written for: Researchers, engineers, graduate students in complexity, applied nonlinear dynamics, neuroscience

A quantitative measure of the accuracy of the rate coefficients and the excess energies is a desirable goal of this analysis. There are two major sources of uncertainties: The atomic and molecular data and the solar irradiance. The cross sections and branching ratios used in this analysis come from many different sources; many of them without any error indications. For this reason, we must confine ourselves to a qualitative indication of the reliability of the results. Specifically we give a quality scale in Table II for the data of each mother molecule; A indicating the highest quality of atomic and molecular data and F the lowest quality. The letter B typically means that the threshold is uncertain. For most molecules the cross section at threshold is very small and the rate coefficient for these molecules is therefore not influenced by this uncertainty. For atomic species the cross section is usually large near threshold, but for these species the threshold is known quite accurately. The letter B, therefore, indicates that the rate coefficient is most likely quite accurate, but the excess energy is less accurately known. The letter C usually means that the branching ratios are not well known. This means that the total rate coefficient is very good, but the rate coefficients and the excess energies for the individual branches are less accurate.

The present set of lectures is devoted to magnetohydrodynamic turbulence in astrophysics with strong emphasis on numerical simulations. The book strives for a balance between state-of-the-art reports and a tutorial approach. It is thus particularly suited as an introduction to the field for nonspecialist researchers and postgraduate students, while experienced scientists will find the book to be a comprehensive source of reference for their research.