Explores the many facets of redox exchanges that drive magma's behavior and evolution, from the origin of the Earth until today The redox state is one of the master variables behind the Earth's forming processes, which at depth concern magma as the major transport agent. Understanding redox exchanges in magmas is pivotal for reconstructing the history and compositional make-up of our planet, for exploring its mineral resources, and for monitoring and forecasting volcanic activity. Magma Redox Geochemistry describes the multiple facets of redox reactions in the magmatic realm and presents experimental results, theoretical approaches, and unconventional and novel techniques. Volume highlights include: Redox state and oxygen fugacity: so close, so far Redox processes from Earth's accretion to global geodynamics Redox evolution from the magma source to volcanic emissions Redox characterization of elements and their isotopes The American Geophysical Union promotes discovery in Earth and space science for the benefit of humanity. Its publications disseminate scientific knowledge and provide resources for researchers, students, and professionals.

This thesis describes novel substrate embedded physical sensors that can be used to monitor different types of cell-based assays non-invasively and label-free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedical research. The author, Maximilian Oberleitner, describes approaches in which the cells are directly grown on different sensor surfaces (gold-film electrodes, shear wave resonators or dye-doped polymer films). This approach, with the reacting cells in particularly close proximity and contact with the sensor surface, is key to a remarkable sensitivity, opening the way for a variety of new applications. This thesis not only introduces the fundamentals of each approach, but it also describes in great detail the design principles and elucidates the boundary conditions of the new sensors.

The work describes the production technology of standard medical radionuclides using reactors and cyclotrons for patient diagnosis and therapy. A special focus lies on the science and technology involved in the development of novel radionuclides for positron emission tomography (PET) and internal targeted radiotherapy. The availability of those radionuclides is opening up new potential in clinical research, especially in neurology, cardiology and oncology. The future perspectives of the developing technology are also discussed.

The thesis presents a tool to create rubble pile asteroid simulants for use in numerical impact experiments, and provides evidence that the asteroid disruption threshold and the resultant fragment size distribution are sensitive to the distribution of internal voids. This thesis represents an important step towards a deeper understanding of fragmentation processes in the asteroid belt, and provides a tool to infer the interior structure of rubble pile asteroids. Most small asteroids are 'rubble piles' - re-accumulated fragments of debris from earlier disruptive collisions. The study of fragmentation processes for rubble pile asteroids plays an essential part in understanding their collisional evolution. An important unanswered question is "what is the distribution of void space inside rubble pile asteroids?" As a result from this thesis, numerical impact experiments can now be used to link surface features to the internal structure and therefore help to answer this question. Applying this model to asteroid Steins, which was imaged from close range by the Rosetta spacecraft, a large hill-like structure is shown to be most likely primordial, while a catena of pits can be interpreted as evidence for the existence of fracturing of pre-existing internal voids.

This thesis describes the application of a Monte Carlo radiative transfer code to accretion disc winds in two types of systems spanning 9 orders of magnitude in mass and size. In both cases, the results provide important new insights. On small scales, the presence of disc winds in accreting white dwarf binary systems has long been inferred from the presence of ultraviolet absorption lines. Here, the thesis shows that the same winds can also produce optical emission lines and a recombination continuum. On large scales, the thesis constructs a simple model of disc winds in quasars that is capable of explaining both the observed absorption and emission signatures - a crucial advance that supports a disc-wind based unification scenario for quasars. Lastly, the thesis also includes a theoretical investigation into the equivalent width distribution of the emission lines in quasars, which reveals a major challenge to all unification scenarios.

This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.

This book presents the first overview of the composition and structure of the Earth's lower mantle. The first part focuses on the study of lower-mantle minerals, identified as inclusions in diamonds from different regions of the world. Three associations are established among the lower-mantle minerals: ultramafic, mafic, and carbonatic. The carbonatic association is of particular interest because it characterizes the media of natural diamond formation. In turn, the second part analyzes the structure of the lower mantle, revealing its heterogeneous composition. It is based on the results of experiments demonstrating phase transitions in lower-mantle minerals, and on seismological data. Deep-seated earthquakes point to the presence within the lower mantle of numerous seismic boundaries caused by mineral structure transitions. In closing, the last part of the book compares observed data with experimental data, highlighting several discrepancies that indicate Earth may have a more complex planetary history than previously assumed, and examining its primarily non-chondritic composition.

Authored by world-class scientists and scholars, the Handbook of Natural Resources, Second Edition, is an excellent reference for understanding the consequences of changing natural resources to the degradation of ecological integrity and the sustainability of life. Based on the content of the bestselling and CHOICE awarded Encyclopedia of Natural Resources, this new edition demonstrates the major challenges that the society is facing for the sustainability of all wellbeing on planet Earth. The experience, evidence, methods, and models used in studying natural resources are presented in six stand-alone volumes, arranged along the main systems: land, water, and air. It reviews state-of-the-art knowledge, highlights advances made in different areas, and provides guidance for the appropriate use of remote sensing data in the study of natural resources on a global scale. The six volumes in this set cover: Terrestrial Ecosystems and Biodiversity; Landscape and Land Capacity; Wetlands and Habitats; Fresh Water and Watersheds; Coastal and Marine Environments; and finally Atmosphere and Climate. Written in an easy-to-reference manner, the Handbook of Natural Resources, Second Edition, as a complete set, is essential for anyone looking for a deeper understanding of the science and management of natural resources. Public and private libraries, educational and research institutions, scientists, scholars, and resource managers will benefit enormously from this set. Individual volumes and chapters can also be used in a wide variety of both graduate and undergraduate courses in environmental science and natural science courses at different levels and disciplines, such as biology, geography, Earth system science, ecology, etc.

This volume comprises the latest developments in both fundamental science and patient-specific applications, discussing topics such as: cellular mechanics; injury biomechanics; biomechanics of heart and vascular system; medical image analysis; and both patient-specific fluid dynamics and solid mechanics simulations. With contributions from researchers world-wide, the Computational Biomechanics for Medicine series of titles provides an opportunity for specialists in computational biomechanics to present their latest methodologies and advancements.

This book on space geodesy presents pioneering geometrical approaches in the modelling of satellite orbits and gravity field of the Earth, based on the gravity field missions CHAMP, GRACE and GOCE in the LEO orbit. Geometrical approach is also extended to precise positioning in space using multi-GNSS constellations and space geodesy techniques in the realization of the terrestrial and celestial reference frame of the Earth. This book addresses major new developments that were taking place in space geodesy in the last decade, namely the availability of GPS receivers onboard LEO satellites, the multitude of the new GNSS satellite navigation systems, the huge improvement in the accuracy of satellite clocks and the revolution in the determination of the Earth's gravity field with dedicated satellite missions.

This book is a passionate account of the scientific breakthroughs that led to the solution of the first protein structures and to the understanding of their function at atomic resolution. The book is divided into self-standing chapters that each deal with a protein or protein family. The subject is presented in a fluid, non-technical style that will engage student and scientists in biochemistry, biophysics, molecular and structure biology and physiology.

This volume presents different studies carried out on induced seismicity, both from experimental and theoretical viewpoints. Several examples of seismic activity induced by underground nuclear explosions, impoundment of artificial reservoirs, and mining activities are given and discussed. Another important subject which is covered is earthquakes induced by other large earthquakes. Further, tectonic stress release in the immediate vicinity of an underground nuclear explosion is treated. The release produces aftershocks of small magnitude, usually for several weeks, occurring a few kilometers within the shot point. This phenomenon is of importance in the context of monitoring a Comprehensive Test Ban Treaty.

The Tide-Dominated Han River Delta provides a thorough analysis of a river delta in which tidal currents have reworked the river-borne sediment, generating characteristic geomorphological and sedimentological signatures in the process. Such "tide-dominated" deltas are common in the modern ocean, forming the substrate upon which entire populations are built. Furthermore, ancient examples contain enormous volumes of hydrocarbon. Despite this, tide-dominated deltas remain less well understood than their wave- and river-dominated counterparts, largely because processes within them are inherently more complex and fewer modern examples have been investigated in detail. This multi-year study by a team of experts in coastal geoscience represents the most complete documentation of a tide-dominated delta to date. Results help advance, and are applicable to, a broad range of fields within sedimentary geology, including clastic sedimentology, seismic and sequence stratigraphy, and coastal geomorphology, in addition to petroleum geology and reservoir engineering.

In this provocative text, a noted neuroscientist reexamines Freud's posthumously published Project of Scientific Psychology in the light of modern neuroscience. This expanded "thermodynamics of the mind" model includes robust conceptions of the cellular and neural processes that accompany creation of consciousness and memory, their contributions to such conditions as depression, dissociative disorders, and schizophrenia, and implications for practice, from imaging to talk-based therapies to pharmacotherapy. Central to this construct is Freud's proposal of specific "omega" neurons as the most volatile carriers of consciousness between mind and brain, which is applied to current issues regarding complexity and executive functioning. In addition, the book is extensively referenced, allowing readers to investigate these and related phenomena in greater detail. Among the topics covered: Neural reductionism in Freud's "Project" and neuropsychoanalysis. Thermodynamics and brain self-organization. Conflicting information and the dissociated mind. The Cartesian model of the mind and the binding problem. Neuroendocrine and immune response to stress. The concept of omega neurons and modern chaos theory. Rigorous, challenging, and occasionally startling, The Brain and Conscious Unity is a milestone in the neuroscience and mind/brain literature to be read and discussed by psychiatrists, psychologists, and neuropsychologists.

This thesis explores fluid distribution along the Nankai-Trough megathrust fault around the Kii Peninsula of Japan, where devastating earthquakes are expected to occur in the near future. Exploring fluid distribution along subduction zones is an important issue because the fluid is considered to control the occurrence of earthquakes. One of the effective strategies to estimate fluid content is retrieving receiver functions (RFs) from seismograms, but in the case of ocean-bottom seismometers (OBSs), noisy P-wave reverberations within the seawater column make such an analysis difficult. The author therefore developed a novel technique to suppress the water reverberations, which allows obtaining the fluid distribution data along a wide depth range on the plate interface. This thesis first presents the new technique, called the water layer filter method, and demonstrates its efficiency by using both synthetic and observation data. Then, using the method, a receiver function image of the Philippine Sea Plate is constructed to reveal dehydration processes of the subducting oceanic crust around the Kii Peninsula. Finally, the author performs high-frequency receiver function inversion analysis. The results indicate the presence of a thin fluid-rich sediment layer along the megathrust fault off the Kii Peninsula that acts as a pathway of fluid. Nowadays, the number of offshore observations is increasing worldwide. In this respect, the attempt to better analyze OBS data employing the new method will become more important in future studies.

NASA Monograph in Aerospace History series, number 37.

This thesis covers a diverse set of topics related to space-based gravitational wave detectors such as the Laser Interferometer Space Antenna (LISA). The core of the thesis is devoted to the preprocessing of the interferometric link data for a LISA constellation, specifically developing optimal Kalman filters to reduce arm length noise due to clock noise. The approach is to apply Kalman filters of increasing complexity to make optimal estimates of relevant quantities such as constellation arm length, relative clock drift, and Doppler frequencies based on the available measurement data. Depending on the complexity of the filter and the simulated data, these Kalman filter estimates can provide up to a few orders of magnitude improvement over simpler estimators. While the basic concept of the LISA measurement (Time Delay Interferometry) was worked out some time ago, this work brings a level of rigor to the processing of the constellation-level data products. The thesis concludes with some topics related to the eLISA such as a new class of phenomenological waveforms for extreme mass-ratio inspiral sources (EMRIs, one of the main source for eLISA), an octahedral space-based GW detector that does not require drag-free test masses, and some efficient template-search algorithms for the case of relatively high SNR signals.

This volume is a new follow-up volume that complements Dynamic Light Scattering (1993) by the same author. The volume is directed to the recent development in the light scattering technique and to describing a wide spectrum of its applications. Both the theoretical development and utilization are traced by authors who are expert in their fields. Development in static light scattering as applied to simple liquids, polymer solutions, and multi-component polymer mixtures are dealt with. The scattering theory of colloidal dispersions is described and scattering from rod-like polyelectolytes is reviewed. There are chapters on concentrated polymer systems, aggregation phenomena, polymer-polymer interactions, polyelectrolytes in solution. Emphasis is given to more complex systems, for example, ternary polymer systems, complex micellar systems, and block copolymers in the ordered and disordered states. Low-angle light scattering is reviewed, as well as simultaneous static and dynamic light scattering. The determination of particle size distributions and combined chromatographic light scattering techniques are also treated.

Cold atmospheric plasma (CAP) emerges as a possible new modality for cancer treatment. This book provides a comprehensive introduction into fundamentals of the CAP and plasma devices used in plasma medicine. An analysis of the mechanisms of plasma interaction with cancer and normal cells including description of possible mechanisms of plasma selectivity is included. Recent advances in the field, the primary challenges and future directions are presented.

The first unified treatment of experimental and theoretical advances in low-temperature chemistry Chemical Dynamics at Low Temperatures is a landmark publication. For the first time, the cumulative results of twenty years of experimental and theoretical research into low-temperature chemistry have been collected and presented in a unified treatment. The result is a text/reference that both offers an overview of the subject and contains sufficient detail to guide practicing researchers toward fertile ground for future research. Topics covered include:
* Developmental history
* Formulation of general problems and the main approximations used to solve them
* Specific features of tunneling chemical dynamics
* One-dimensional tunneling in the path integral formalism
* Special problems of two- and multidimensional tunneling
* An extended presentation of pertinent experimental results

This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen biofilms; killing infectious pathogens through DNA damage; bacterial surfaces in host-pathogen interactions; bacterial gene regulation by riboswitches; transcription regulation in enterobacterial pathogens; the bacterial flagellar motor; initial surface colonization by bacteria; Salmonella Typhi host restrictions; as well as monitoring proton motive force in bacteria; microbial pathogens using digital holography; mathematical modelling of microbial pathogen motility; neutron reflectivity in studying bacterial membranes; force spectroscopy in studying infection and 4D multi-photon imaging to investigate immune responses. The focus is on the development and application of complex techniques and protocols at the interface of life sciences and physics, which increase the physiological relevance of biophysical investigations.

The focus of his prize-winning thesis is on observations and modeling of binary millisecond pulsars. But in addition, John Antoniadis covers a wide range of observational measurements of binary compact stars systems and tests of General Relativity, like indirect measurements of gravitational wave emission and posing the most stringent constraints on Scalar-Tensor gravity theories. Among others, he presents a system that hosts the most massive neutron star known to date, which has important ramifications for strong-field gravity and nuclear physics. This impressive work was awarded the Otto-Hahn Medal of the Max-Planck Society and the Best PhD in Gravity, Particle and Atomic physics award by the German Physics Society (DPG).

The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. It introduces into cell biology over thirty key concepts, principles and laws imported from physics, chemistry, computer science, linguistics, semiotics and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for basic living processes such as ligand-receptor interactions, enzymic catalysis, force-generating mechanisms in molecular motors, chromatin remodelling, and signal transduction. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotherapeutics and personalized medicine.

This comprehensive book offers a clear account of the theory and applications of advanced metal forming. It provides a detailed discussion of specific forming processes, such as deep drawing, rolling, bending extrusion and stamping. The author highlights recent developments of metal forming technologies and explains sound, new and powerful expert system techniques for solving advanced engineering problems in metal forming. In addition, the basics of expert systems, their importance and applications to metal forming processes, computer-aided analysis of metalworking processes, formability analysis, mathematical modeling and case studies of individual processes are presented.

""What about the twenty-first century? Will we finally accept our responsibilities as guardians of planet Earth, the biological living trust, for the beneficiaries, the children of today, tomorrow, and beyond? Or, will it too be a century of lethal, economic struggle among the polarized positions of the supremely dysfunctional among us? Are they--once again--to be allowed to determine the legacy we, as a society, as a nation, bequeath those who follow us? The choice is ours, the adults of the world. How shall we choose?""

So writes Chris Maser in this compelling study of three interactive spheres of the ecosystem: atmosphere (air), litho-hydrosphere (rock that comprises the restless continents and the water that surrounds them), and biosphere (all life sandwiched in between).

Rich in detail and insightful analogies, "Earth in Our Care" addresses key issues including land-use policies, ecological restoration, forest management, local living, and sustainability thinking. Exploring our interconnectedness with the Earth, Maser examines today's problems and, more importantly, provides solutions for the future.