Sulfurtransferases: Essential Enzymes for Life stands as the first
comprehensive resource on this increasingly important class of
enzymes. Following an introduction to the field from the Editors,
each chapter covers a specific sulfurtransferase, including its
basic biology and roles in healthy functioning, disease, drug
discovery, and other biotechnological applications. The
physiological function for each enzyme is considered in depth,
along with regulation mechanisms, pharmacological inhibitors, and
pathology and conditions related to altered enzymatic activity.
Sulfurtransferases discussed include rhodanese, MST,
thiosulfate-thiol sulfurtransferase, tRNA uracil
4-sulfurtransferase, thiosulfate-dithiol sulfurtransferases, biotin
synthase, cysteine desulfurase, lipoyl synthase, molybdenum
cofactor sulfurtransferase, thiazole synthase, molybdopterin
synthase sulfurtransferase, molybdopterin synthase, tRNA-uridine
2-sulfurtransferase, tRNA-5-taurinomethyluridine
2-sulfurtransferase, tRNA-5-methyluridine (54) 2-sulfurtransferase,
and L-aspartate semialdehyde sulfurtransferase, among others. Here,
researchers will discover key knowledge and recent advances to
bring forward new studies on this increasingly relevant class of
enzymes, while clinicians may apply new findings in medical
practice.
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