This third and final volume in the "Ion Transport in Tumor Biology"
collection presents novel diagnostic and therapeutic approaches in
cancer based on the exploitation of ion transport proteins. The
authors critically examine several transportome members,
particularly Na+, K+, Ca2+, and Cl- channels, as well as organic
solute carriers regarding their suitability as therapeutic targets.
Synergistic effects resulting from the combined use of classical
cytostatics with ion transport-inhibiting drugs are pointed out,
and the capability of bispecific antibodies to function as
anticancer drugs is discussed. As readers will also learn,
the use of ion channel inhibitors could improve the outcome of
radiotherapy because the development of radio-resistance during
radiotherapeutic treatment often correlates with increases in the
expression levels and conductance of ion channels. The
translational topics of this volume form a bridge between
biochemical research and therapeutic application. As part of a
three-volume collection, this book will fascinate members of the
active research community, as well as clinicians in the cancer
field.
General
Imprint: |
Springer International Publishing AG
|
Country of origin: |
Switzerland |
Series: |
Reviews of Physiology, Biochemistry and Pharmacology, 183 |
Release date: |
May 2023 |
First published: |
2022 |
Editors: |
Christian Stock
• Luis A. Pardo
|
Dimensions: |
235 x 155mm (L x W) |
Pages: |
277 |
Edition: |
1st ed. 2022 |
ISBN-13: |
978-3-03-103996-6 |
Categories: |
Books
|
LSN: |
3-03-103996-3 |
Barcode: |
9783031039966 |
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